Lloyd, Julie - University of Essex - School of Biological Sciences

个人简介

Posts & Training I have been in the Department since 1989; for the first 3 years on a Royal Society University Research Fellowship, until I was appointed as a Lecturer. Before that I was a post-doc in Cambridge (at the then Plant Breeding Institute) having obtained my Ph.D. at University College London. Teaching My teaching in the Department is in the areas of genetics, molecular biology and plant biotechnology. I also have responsibility for organising the final year of the Biological degree schemes in the Department.

研究领域

My main research interests are centred around plant molecular biology and the control of gene expression. Much of this has focussed on the nuclear genes encoding enzymes involved in carbon fixation in the chloroplast. Together with my main collaborator, Dr Christine Raines, who is also in this Department, many of these genes have been cloned and characterised. Studies on their expression, which is complex (involving chloroplast development, metabolic repression and light-regulation) have made use of transient protoplast assays and transgenic plants. Current research projects in the lab have moved this work on to the identification of DNA binding proteins interacting with the upstream regions of the genes. We are now actively trying to clone these factors in an effort to understand more about their role in regulating gene expression. The other major area of plant molecular biology at Essex is making use of antisense in transgenic plants to determine the relative importance of particular enzymes in controlling carbon fixation. Other research interests are in: Do higher plants have cellular phosphate sensing pathways? Molecular cloning of plant genes by complementation of yeast mutants I have a number of research students in these areas, and I would be pleased to receive applications from prospective students or visiting researchers on any of these subjects.

近期论文

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Harrison, EP, Willingham, NM, Lloyd, JC & Raines CA (1996) Reduced SBPase levels in transgenic tobacco lead to decreased photosynthetic capacity and altered carbohydrate accumulation. (submitted) Jones, PJ, Lloyd, JC & Raines CA (1996) Glucose feeding of intact wheat plants represses the expression of a number of Calvin cycle genes. Plant Cell Environ 19, 231-236. Willingham, NM, Lloyd JC & Raines CA (1994) Molecular cloning of the Arabidopsis thaliana sedoheptulose-1,7-bisphosphatase gene and expression studies in wheat and Arabidopsis thaliana. Plant Mol Biol 26, 1191-1200. Miles, AJ, Potts, S, Willingham, NM, Raines CA & Lloyd JC (1993) A light and developmentally regulated DNA-binding interaction is common to the upstream sequences of the wheat Calvin cycle bisphosphatase genes. Plant Mol Biol 22, 507-516.