Mccormick, Peter - University of East Anglia

个人简介

Peter studied French and Chemistry at Washington University in St. Louis (USA), and obtained a PhD in Biochemistry and Biophysics from Texas A&M University (USA) working in the lab of Arthur E. Johnson and studying the biogenesis of membrane proteins. In 2003 began a post-doctoral fellowship in the lab of Juan Bonifacino at the National Institutes of Health (USA) studying trafficking of membrane proteins. He then moved to the National Cancer Insitute (USA) where he began working on G-protein coupled receptors (GPCRs) in the lab of Giovanna Tosato. In 2010, he obtained a prestigious Ramon y Cajal fellowship from the Spanish government. He moved to Barcelona where he continued his work on GPCRs, focusing on the biological role and mechanisms of their dimerization. In 2013 he was appointed a Lecturer in Cell Biology. His research involves the identification and characterization of G-protein coupled receptor dimers as novel drug targets in a variety of pathologies.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Gemma Navarro, Estefanía Moreno, Jordi Bonaventura, Marc Brugarolas, Daniel Farré, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carme Lluís, Sergi Ferre, Rafael Franco, Enric Canela, Peter J. McCormick. Cocaine inhibits D2 receptor signaling via sigma-1-dopamine D2 receptor heteromersPloS One, 2013 Apr 18;8(4):e61245. Lucía Callén, Estefanía Moreno, Pedro Barroso-Chinea, David Moreno-Delgado, Antoni Cortés, Josefa Mallol, Vicent Casadó, José Luis Lanciego, Rafael Franco, Carmen Lluis, Enric I. Canela, and Peter J. McCormick. Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in BrainThe Journal of Biological Chemistry 287, 25 (June 15, 2012): 20851–20865. Sergio González, David Moreno-Delgado, Estefanía Moreno, Kamil Pérez-Capote, Rafael Franco, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carme Lluís, Jordi Ortiz, Sergi Ferré, Enric Canela, Peter J. McCormickCircadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal GlandPLoS Biology 10, 6 (June 19, 2012): e1001347. 8. (Faculty of 1000 « Must Read » and Featured article in PLoS Biology) S González, C Rangel-Barajas, M Peper, R Lorenzo, E Moreno, F Ciruela, J Borycz, J Ortiz, C Lluís, R Franco, PJ McCormick, ND Volkow, M Rubinstein, B Floran, S Ferré. Dopamine D4 Receptor, but Not the ADHD-associated D4.7 Variant, Forms Functional Heteromers with the Dopamine D2S Receptor in the BrainMolecular Psychiatry 17, 6 (June 2012): 650–662. ( Selected for Journal Cover) Navarro, Gemma, Estefanía Moreno, Marisol Aymerich, Daniel Marcellino, Peter J McCormick, Josefa Mallol, Antoni Cortés, et al. Direct Involvement of Sigma-1 Receptors in the Dopamine D1 Receptor-mediated Effects of CocaineProc. Nat. Acad. Sci.USA 107, 43 (October 26, 2010): 18676–18681. ( Faculty of 1000 « Must Read ») Rafael Franco, Eva Martínez, Ana Ricobaraza, and Peter J. McCormickChallenges in the development of heteromer-GPCR-based drugsOligomerization in Health and Disease/ Progress in Molecular Biology and Translational Science, 2013;117:143-62.