Modi, Gyan Prakash - Indian Institute of Technology BHU - Department of Pharmaceutical Engineering and Technology

个人简介

Educational Qualifications B.Pharm. (2004) : Sanjiveeni College of Pharmaceutical Sciences, Khetri /University of Rajasthan, Jaipur M.Pharm. (2007) : IT-BHU/BHU, Varanasi Ph D. (2013): Department of Pharmaceutical Sciences/Wayne State University, Detroit, MI, USA

研究领域

Drug Discovery Against Central Nervous System Disorders Protein Aggregation and It’s Role in CNS diseases Design and Development of Antimicrobial Agents

近期论文

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Gyan Modi, Tamara Antonio, Maarten Reith, Aloke Dutta, Structural modifications of neuroprotective anti-Parkinsonian (-)-N6-(2-(4-(Biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264): An effort towards the improvement of brain penetration property of the parent molecule, J. Med. Chem., 2014, 57, 1557-1572 Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E.A. Reith, Aloke K. Dutta, Multifunctional D2/D3 agonist D-520 with high in vivo efficacy: Modulation of toxicity of alpha synuclein aggregates, ACS Chemical Neuroscience, 2014, 5, 700-717 Gyan Modi, Horrick Sharma, Prashant Kharkar, Aloke K. Dutta, Understanding the structural requirements of hybrid (S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol and its analogs as D2/D3 receptor ligands: A three-dimensional quantitative structure-activity relationship (3D QSAR) investigation, MedChemComm, 2014, 5, 1384-1399