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个人简介

Professor David J Richardson is a bacterial biochemist who has used a range of disciplines to unravel respiratory processes of anaerobic bacteria from both soils and marine environments and the human gastro-intestinal tract. His work has revealed the great adaptive flexibility of highly branched pathways of respiratory chains by the isolation, structural characterisation and functional analysis of their enzymes and electron transfer proteins. His work on the nitrogen cycle as well as the mechanisms by which bacteria use insoluble extracellular minerals as respiratory electron acceptors is now showing major impacts in environmental and climate science, industrial biotechnology and synthetic biology. Richardson’s contributions have been recognised by the award of the Society for General Microbiology Fleming Medal (1999), a Royal Society Wolfson Merit Fellowship (2008-2013), and by appointment to the Council of the Biotechnology and Biological Sciences Research Council (2012). He has published >200 peer-reviewed papers that have been cited more than 9000 times. His research currently has an H-index of 54 (Google Scholar, October 2013). Career History From August 2012 Deputy Vice Chancellor, University of East Anglia From August 2011 Pro-Vice Chancellor, Enterprise & Engagement, University of East Anglia Jan 2008-July 2011 Executive Dean, Faculty of Science, University of East Anglia Aug 2004-Dec 2007 Associate Dean, Faculty of Science, University of East Anglia June 2001-present Professor of Microbial Biochemistry, School of Biological Sciences, University of East Anglia Oct 1998-June 2001 Reader, School of Biological Sciences, University of East Anglia June 1991-Oct 1998 Lecturer, School of Biological Sciences, University of East Anglia Oct 1988-May 1991 Post-Doctoral Research Associate, Department of Biochemistry, University of Oxford

研究领域

Respiratory flexibility in Bacteria Electron transfer at microbe-mineral interfaces New approaches to studies of the nitrogen cycle in wastewater treatment plants Biochemistry, genetics, and molecular ecology of bacterial denitrification The regulation of bacterial nitrous oxide production Novel methods for second generation bioalcohol production Nitric oxide metabolism in pathogens and leguminous root nodules Bacterial semi-conductor mediated photocatalysis Enzyme based biosensors for nitrogen oxides and nitrogen oxyanions Microbial electrocatalysis

近期论文

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Cabrera, J. J., Salas, A., Torres, M. J., Bedmar, E. J., Richardson, D. J., Gates, A. J., Delgado, M. J.(2016)An integrated biochemical system for nitrate assimilation and nitric oxide detoxification in Bradyrhizobium japonicumin Biochemical Journal473.pp. 297-309 Full Text UEA Repository(Article) White, G., Edwards, M., Gomez Perez, L., Richardson, D., Butt, J., Clarke, T.(2016)Mechanisms of Bacterial Extracellular Electron Exchange.ElsevierISBN 978-0-12-804823-8 Full Text UEA Repository(Chapter)Tropea, A., Wilson, D., Cicero, N., Potortì, A. G., La Torre, G. L., Dugo, G., Richardson, D., Waldron, K. W.(2016)Development of minimal fermentation media supplementation for ethanol production using two Saccharomyces cerevisiae strainsin Natural Product Research30.pp. 1009-1016 Full Text UEA Repository(Article) Torres, M., Simon, J., Rowley, G., Bedmar, E., Richardson, D., Gates, A., Delgado, M.(2016)Nitrous Oxide Metabolism in Nitrate-Reducing Bacteria: Physiology and Regulatory Mechanismsin Advances in Microbial Physiology68.pp. 353-432 Full Text UEA Repository(Article) Gao, S., Yuan Ho, J., Fan, L., Richardson, D. J., Yuan, Z., L Bond, P.(2016)Antimicrobial effects of free nitrous acid on Desulfovibrio vulgaris: Implications for sulfide-induced corrosion of concretein Applied and Environmental Microbiology82.pp. 5563-5575 Full Text UEA Repository(Article) Field, S., Ryden, P., Wilson, D. C., James, S. A., Roberts, I., Richardson, D., Waldron, K., Clarke, T.(2015)Identification of furfural resistant strains of Saccharomyces cerevisiae and Saccharomyces paradoxus from a collection of environmental and industrial isolatesin Biotechnology for Biofuels8. Full Text UEA Repository(Article) Pan, Y., Ni, B., Lu, H., Chandran, K., Richardson, D., Yuan, Z.(2015)Evaluating two concepts for the modelling of intermediates accumulation during biological denitrification in wastewater treatmentin Water Research71.pp. 21-31 Full Text UEA Repository(Article) Lockwood, C., Burlat, B., Cheesman, M., Kern, M., Simon, J., Clarke, T., Richardson, D., Butt, J.(2015)Resolution of Key Roles for the Distal Pocket Histidine in Cytochrome c Nitrite Reductasesin Journal of the American Chemical Society137.pp. 3059–3068 Full Text UEA Repository(Article) Beckwith, C., Edwards, M., Lawes, M., Shi, L., Butt, J., Richardson, D., Clarke, T.(2015)Characterisation of MtoD from Sideroxydans lithotrophicus: a cytochrome c electron shuttle used in lithoautotrophic growthin Frontiers in Microbiology6. Full Text UEA Repository(Article) Wang, Z., Shi, Z., Shi, L., White, G., Richardson, D., Clarke, T., Fredrickson, J., Zachara, J.(2015)Effects of soluble flavin on heterogeneous electron transfer between surface exposed bacterial cytochromes and iron oxidesin Geochimica et Cosmochimica Acta163.pp. 299–310 Full Text UEA Repository(Article) Edwards, M., White, G., Norman, M., Tome-Fernandez, A., Ainsworth, E., Shi, L., Fredrickson, J., Zachara, J., Butt, J., Richardson, D., Clarke, T.(2015)Redox Linked Flavin Sites in Extracellular Decaheme Proteins Involved in Microbe-Mineral Electron Transferin Scientific Reports5. Full Text UEA Repository(Article) Butt, J., Gates, A., Marritt, S., Richardson, D.(2015)Enzyme Film ElectrochemistryWiley-Blackwellpp. 105-120ISBN 978-0-470-57845-2(Chapter (peer-reviewed))Edwards, M. J., Baiden, N., Johs, A., Tomanicek, S. J., Liang, L., Shi, L., Fredrickson, J. K., Zachara, J. M., Gates, A. J., Butt, J. N., Richardson, D. J., Clarke, T. A.(2014)The X-ray crystal structure of Shewanella oneidensis OmcA reveals new insight at the microbe-mineral interfacein FEBS Letters588.pp. 1886-1890 Full Text UEA Repository(Article) Liu, Y., Wang, Z., Liu, J., Levar, C., Edwards, M., Babauta, J., Kennedy, D., Shi, Z., Bayenal, H., Bond, D. R., Clarke, T., Butt, J., Richardson, D., Rosso, K., Zachara, J., Fredrickson, J., Shi, L.(2014)A trans-outer membrane porin-cytochrome protein complex for extracellular electron transfer by Geobacter sulfurreducens PCAin Environmental Microbiology Reports6.pp. 776-785 Full Text UEA Repository(Article) White, G., Shi, Z., Shi, L., Wang, Z., Dohnalkova, A. C., Marshall, M. J., Fredrickson, J. K., Zachara, J. M., Butt, J., Richardson, D., Clarke, T., cytochrome, mineral respiration(2013)Rapid electron exchange between surface-exposed bacterial cytochromes and Fe(III) minerals.in Proceedings of the National Academy of Sciences of the United States of America (PNAS)110.pp. 6346-6351 Full Text UEA Repository(Article) Richardson, D., Butt, J., Clarke, T.(2013)Controlling electron transfer at the microbe-mineral interfacein Proceedings of the National Academy of Sciences of the United States of America (PNAS)110.pp. 7537-7538 Full Text UEA Repository(Article) Mcmillan, D. G. G., Marritt, S. J., Firer-sherwood, M. A., Shi, L., Richardson, D., Evans, S. D., Elliott, S. J., Butt, J. N., Jeuken, L. J. C.(2013)Protein–Protein Interaction Regulates the Direction of Catalysis and Electron Transfer in a Redox Enzyme Complexin Journal of the American Chemical Society135.pp. 10550-10556 Full Text UEA Repository(Article) Woolfenden, H., Gates, A., Bocking, C., Blyth, M., Richardson, D., Moulton, V.(2013)Modeling the effect of copper availability on bacterial denitrificationin MicrobiologyOpen2.pp. 756-765 Full Text UEA Repository(Article) Gates, A. J., Marritt, S. J., Bradley, J. M., Shi, L., McMillan, D. G. G., Jeuken, L. J. C., Richardson, D. J., Butt, J. N.(2013)Electrode assemblies composed of redox cascades from microbial respiratory electron transfer chainsin Biochemical Society Transactions41.pp. 1249-1253 Full Text UEA Repository(Article)

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