Rowley, Gary - University of East Anglia - School of Biological Sciences

个人简介

Lecturer, School of Biological Sciences, UEA (2007-) Postdoctoral Fellow, Institute of Food Research, UK (2004-2007) MRes & Ph.D. - University of Glasgow, UK (2000-2004) B.Sc. – Biomedical Science, University of Bradford, UK (1996-2000)

研究领域

I am a Molecular Microbiologist and my primary research interests relate to the environmental regulation of enteric pathogens such as Salmonella Typhimurium. We are particular interested in dissecting how various stresses and stimuli impact on virulence phenotypes, and whether they can be manipulated to develop novel antimicrobial or vaccine targets.

近期论文

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Torres, M., Simon, J., Rowley, G., Bedmar, E., Richardson, D., Gates, A., Delgado, M.(2016)Nitrous Oxide Metabolism in Nitrate-Reducing Bacteria: Physiology and Regulatory Mechanismsin Advances in Microbial Physiology68.pp. 353-432 Full Text UEA Repository(Article) Runkel, S., Wells, H., Rowley, G.(2013)Living with stress: A lesson from the enteric pathogen salmonella entericain Advances in Applied Microbiology83.pp. 87-144 Full Text UEA Repository(Article) Sullivan, M. J., Gates, A. J., Appia-Ayme, C., Rowley, G., Richardson, D. J.(2013)Copper control of bacterial nitrous oxide emission and its impact on vitamin B12-dependent metabolismin Proceedings of the National Academy of Sciences of the United States of America (PNAS)110.pp. 19926-31 Full Text UEA Repository(Article) Rowley, G., Hensen, D., Felgate, H., Arkenberg, A., Appia‑Ayme, C., Prior, K., Harrington, C., Field, S., Butt, J., Baggs, E., Richardson, D.(2012)Resolving the contributions of the membrane-bound and periplasmic nitrate reductase systems to nitric oxide and nitrous oxide production in Salmonella enterica serovar Typhimuriumin Biochemical Journal441.pp. 755-762 Full Text UEA Repository(Article) Appia‑Ayme, C., Hall, A., Patrick, E., Rajadurai, S., Clarke, T., Rowley, G.(2012)ZraP is a periplasmic molecular chaperone and a repressor of the zinc-responsive two-component regulator ZraSRin Biochemical Journal442.pp. 85-93 Full Text UEA Repository(Article) Felgate, H., Giannopoulos, G., Sullivan, M., Gates, A., Clarke, T., Baggs, E., Rowley, G., Richardson, D.(2012)The impact of copper, nitrate and carbon status on the emission of nitrous oxide by two species of bacteria with biochemically distinct denitrification pathwaysin Environmental Microbiology14.pp. 1788-1800 Full Text UEA Repository(Article) Stremińska, M., Felgate, H., Rowley, G., Richardson, D., Baggs, E.(2012)Nitrous oxide production in soil isolates of nitrate-ammonifying bacteriain Environmental Microbiology Reports4.pp. 66-71 Full Text UEA Repository(Article) Perkins, T. T., Davies, M., Klemm, E., Rowley, G., Wileman, T., James, K., Keane, T., Maskell, D., Hinton, J., Dougan, G., Kingsley, R.(2012)Chip-seq and transcriptome analysis of the OmpR regulon od Salmonella enterica serovas Typhi and Typhimurium reveals accessory genes implicated in host colonizationin Molecular Microbiology87.pp. 526-538 Full Text UEA Repository(Article) Arkenberg, A., Runkel, S., Richardson, D., Rowley, G.(2011)The production and detoxification of a potent cytotoxin, nitric oxide, by pathogenic enteric bacteriain Biochemical Society Transactions39.pp. 1876-1879 Full Text UEA Repository(Article) Appia-Ayme, C., Patrick, E., Sullivan, M., Alston, M., Field, S., AbuOun, M., Anjum, M., Rowley, G.(2011)Novel Inducers of the Envelope Stress Response BaeSR in Salmonella Typhimurium: BaeR Is Critically Required for Tungstate Waste Disposalin PLoS ONE6. Full Text UEA Repository(Article) Rowley, G., Skovierova, H., Stevenson, A., Rezuchova, B., Homerova, D., Lewis, C., Sherry, A., Kormanec, J., Roberts, M.(2011)The periplasmic chaperone Skp is required for successful Salmonella Typhimurium infection in a murine typhoid modelin Microbiology157.pp. 848-858 Full Text UEA Repository(Article) Bowden, S., Rowley, G., Hinton, J., Thompson, A.(2009)Glucose and glycolysis are required for the successful infection of macrophages and mice by Salmonella enterica serovar typhimuriumin Infection and Immunity77.pp. 3117-3126 Full Text UEA Repository(Article) Lewis, C., Skovierova, H., Rowley, G., Rezuchova, B., Homerova, D., Stevenson, A., Spencer, J., Farn, J., Kormanec, J., Roberts, M.(2009)Salmonella enterican Serovar Typhimurium HtrA: regulation of expression and role of the chaperone and protease activities during infectionin Microbiology155(Pt 3).pp. 873-881 Full Text UEA Repository(Article) Prior, K., Hautefort, I., Hinton, J., Richardson, D., Rowley, G.(2009)All Stressed Out. Salmonella Pathogenesis and Reactive Nitrogen Speciesin Advances in Microbial Physiology56.pp. 1-28 Full Text UEA Repository(Article) Lewis, C., Skovierova, H., Rowley, G., Rezuchova, B., Homerova, D., Stevenson, A., Sherry, A., Kormanec, J., Roberts, M.(2008)Small outer-membrane lipoprotein, SmpA, is regulated by oE and has a role in cell envelope integrity and virulence of Salmonella enterica serovar Typhimuriumin Microbiology154.pp. 979-988 Full Text UEA Repository(Article) Mills, P., Rowley, G., Spiro, S., Hinton, J., Richardson, D.(2008)A combination of cytochrome c nitrite reductase (NrfA) and flavorubredoxin (NorV) protects Salmonella enterica serovar Typhimurium against killing by NO in anoxic environmentsin Microbiology154.pp. 1218-1228 Full Text UEA Repository(Article) McMeehan, A., Roberts, M., Cogan, T., Jorgensen, F., Stevenson, A., Lewis, C., Rowley, G., Humphrey, T.(2007)Role of the alternative sigma factors sigmaE and sigmaS in survival of Salmonella enterica serovar Typhimurium during starvation, refrigeration and osmotic shockin Microbiology153.pp. 263-269 Full Text UEA Repository(Article) Balbontin, R., Rowley, G., Pucciarelli, M., Lopez-Garrido, J., Wormstone, Y., Lucchini, S., Garcia-Del Portillo, F., Hinton, J., Casadesus, J.(2006)DNA adenine methylation regulates virulence gene expression in Salmonella enterica serovar Typhimuriumin Journal of Bacteriology188.pp. 8160-8168 Full Text UEA Repository(Article) Lucchini, S., Rowley, G., Goldberg, M., Hurd, D., Harrison, M., Hinton, J.(2006)H-NS mediates the silencing of laterally acquired genes in bacteriain PLoS Pathogens2. Full Text UEA Repository(Article) Rowley, G., Spector, M., Kormanec, J., Roberts, M.(2006)Pushing the envelope: extracytoplasmic stress responses in bacterial pathogensin Nature Reviews Microbiology4.pp. 383-394 Full Text UEA Repository(Article)