Vogler, Alfried - Imperial College London - Department of Life Sciences, Biology, Ecology and Environmental Biology, Microbiology, Zoology

个人简介

I am a molecular systematist working on the phylogeny and evolution of species diversity in insects. My specific interest is the order Coleoptera (beetles), the arguably largest radiation of animal species on Earth, which I use as a model for an evolutionary understanding of the great diversity of living organisms. I apply genomics and phylogenetic analysis, working at all hierarchical levels, from populations to basal relationships of insect orders. Novel high-throughput sequencing methods are constantly opening up new avenues for studying taxonomy and biodiversity, in particular in poorly known groups of arthropods, such as the tropical forest canopy or the soil. Metagenomic shotgun sequencing permits the study of entire complex communities in bulk for the analysis of species richness and phylogeny directly from an environmental sample (‘soup-to-tree’). Equally, we are using environmental DNA (eDNA) and qPCR or metabarcoding approaches to characterize complex communities from soil and water in benthic marine and freshwater habitats, or to study gut content of insects and mammals. I have a joint appointment with the Natural History Museum (NHM) London where I conduct most of my research.

研究领域

My group uses molecular sequencing for phylogenetic and evolutionary analyses, to establish relationships of living organisms and their genes and genomes. Large-scale DNA analyses are also being used in taxonomy ("DNA taxonomy"), providing diagnostic sequences for each species on Earth. We are applying these DNA approaches to the molecular systematics of insects and specifically the order Coleoptera (beetles). The insects are extremely species rich and include well over half of all known species of animals, providing an enormous challenge for DNA approaches simply due to their great diversity. We are asking, how is the great species richness of organismal lineages distributed on Earth, and what are the evolutionary causes of diversity? Our research group is located at the Natural History Museum. The research programme links to the broad questions traditionally addressed in Entomology about the taxonomy, phylogenetics and evolutionary biology of insects. For example, we are using a combined bioinformatics and molecular systematics approach to study the deep level phylogeny of the nearly 200 families and major groups of Coleoptera, based on thousands of taxa and large-scale tree searches. Similar questions about basal relationships can be addressed with genomic approaches. Our group continually develops new applications for DNA sequencing at the genomic level. For example, we were among the first to use transcriptome sequencing and dense taxon sampling to establish deep-level relationships of Coleoptera and other insect groups. Likewise we use next-generation sequencing technology for routine analysis of whole-mitochondrial genomes. Our research also addresses the evolutionary history at the level of species and populations. We are studying the insect fauna of Madagascar, to establish the causes of endemicity and diversity, based on large-scale DNA sequencing of entire communities. Similar approaches are used in other regions (mainland Europe, Aegean islands, Papua New Guinea, Falkland Islands, Panama, etc.) to establish patterns of diversity for comparisons of different regions and ecological groups. DNA provides a universal character system applicable from the deepest levels of lineage splits to the species and populations, and linking different portions of the genome. This provides a synthesis of diversity on all hierarchical levels, for a more complete evolutionary understanding of the living world.

近期论文

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Ahrens D, Fujisawa T, Krammer H-J, Eberle J, Fabrizi S, Vogler APet al., 2016, Rarity and Incomplete Sampling in DNA-Based Species Delimitation, SYSTEMATIC BIOLOGY, Vol: 65, Pages: 478-494, ISSN: 1063-5157 Andujar C, Arribas P, Linard B, Kundrata R, Bocak L, Vogler APet al., 2016, The mitochondrial genome of Iberobaenia (Coleoptera: Iberobaeniidae): first rearrangement of protein-coding genes in the beetles., Mitochondrial DNA A DNA Mapp Seq Anal, Pages: 1-3 Andujar C, Faille A, Perez-Gonzalez S, Zaballos JP, Vogler AP, Ribera Iet al., 2016, Gondwanian relicts and oceanic dispersal in a cosmopolitan radiation of euedaphic ground beetles, MOLECULAR PHYLOGENETICS AND EVOLUTION, Vol: 99, Pages: 235-246, ISSN: 1055-7903 Arribas P, Andujar C, Hopkins K, Shepherd M, Vogler APet al., 2016, Metabarcoding and mitochondrial metagenomics of endogean arthropods to unveil the mesofauna of the soil, METHODS IN ECOLOGY AND EVOLUTION, Vol: 7, Pages: 1071-1081, ISSN: 2041-210X Bidegaray-Batista L, Sanchez-Gracia A, Santulli G, Maiorano L, Guisan A, Vogler AP, Arnedo MAet al., 2016, Imprints of multiple glacial refugia in the Pyrenees revealed by phylogeography and palaeodistribution modelling of an endemic spider, MOLECULAR ECOLOGY, Vol: 25, Pages: 2046-2064, ISSN: 0962-1083 Bocak L, Kundrata R, Fernandez CA, Vogler APet al., 2016, The discovery of Iberobaeniidae (Coleoptera: Elateroidea): a new family of beetles from Spain, with immatures detected by environmental DNA sequencing, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 283, ISSN: 0962-8452 Bocakova M, Bocak L, Gimmel ML, Motyka M, Vogler APet al., 2016, Aposematism and mimicry in soft-bodied beetles of the superfamily Cleroidea (Insecta), ZOOLOGICA SCRIPTA, Vol: 45, Pages: 9-21, ISSN: 0300-3256 Breeschoten T, Doorenweerd C, Tarasov S, Vogler APet al., 2016, Phylogenetics and biogeography of the dung beetle genus Onthophagus inferred from mitochondrial genomes, MOLECULAR PHYLOGENETICS AND EVOLUTION, Vol: 105, Pages: 86-95, ISSN: 1055-7903 Crampton-Platt A, Yu DW, Zhou X, Vogler APet al., 2016, Mitochondrial metagenomics: letting the genes out of the bottle, GIGASCIENCE, Vol: 5 Gill RJ, Baldock KCR, Brown MJF, Cresswell JE, Dicks LV, Fountain MT, Garratt MPD, Gough LA, Heard MS, Holland JM, Ollerton J, Stone GN, Tang CQ, Vanbergen AJ, Vogler AP, Woodward G, Arce AN, Boatman ND, Brand-Hardy R, Breeze TD, Green M, Hartfield CM, O'Connor RS, Osborne JL, Phillips J, Sutton PB, Potts SGet al., 2016, Protecting an Ecosystem Service: Approaches to Understanding and Mitigating Threats to Wild Insect Pollinators, ECOSYSTEM SERVICES: FROM BIODIVERSITY TO SOCIETY, PT 2, Vol: 54, Pages: 135-206, ISSN: 0065-2504 Linard B, Arribas P, Andujar C, Crampton-Platt A, Vogler APet al., 2016, Lessons from genome skimming of arthropod-preserving ethanol, MOLECULAR ECOLOGY RESOURCES, Vol: 16, Pages: 1365-1377, ISSN: 1755-098X Miller KE, Hopkins K, Inward DJG, Vogler APet al., 2016, Metabarcoding of fungal communities associated with bark beetles, ECOLOGY AND EVOLUTION, Vol: 6, Pages: 1590-1600, ISSN: 2045-7758 Paula DP, Linard B, Crampton-Platt A, Srivathsan A, Timmermans MJTN, Sujii ER, Pires CSS, Souza LM, Andow DA, Vogler APet al., 2016, Uncovering Trophic Interactions in Arthropod Predators through DNA Shotgun-Sequencing of Gut Contents, PLOS ONE, Vol: 11, ISSN: 1932-6203 Song F, Li H, Jiang P, Zhou X, Liu J, Sun C, Vogler AP, Cai Wet al., 2016, Capturing the Phylogeny of Holometabola with Mitochondria! Genome Data and Bayesian Site-Heterogeneous Mixture Models, GENOME BIOLOGY AND EVOLUTION, Vol: 8, Pages: 1411-1426, ISSN: 1759-6653 Srivathsan A, Ang A, Vogler AP, Meier Ret al., 2016, Fecal metagenomics for the simultaneous assessment of diet, parasites, and population genetics of an understudied primate, FRONTIERS IN ZOOLOGY, Vol: 13, ISSN: 1742-9994 Timmermans MJTN, Barton C, Haran J, Ahrens D, Culverwell CL, Ollikainen A, Dodsworth S, Foster PG, Bocak L, Vogler APet al., 2016, Family-Level Sampling of Mitochondrial Genomes in Coleoptera: Compositional Heterogeneity and Phylogenetics, GENOME BIOLOGY AND EVOLUTION, Vol: 8, Pages: 161-175, ISSN: 1759-6653 Timmermans MJTN, Viberg C, Martin G, Hopkins K, Vogler APet al., 2016, Rapid assembly of taxonomically validated mitochondrial genomes from historical insect collections, BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY, Vol: 117, Pages: 83-95, ISSN: 0024-4066 Andujar C, Arribas P, Ruzicka F, Crampton-Platt A, Timmermans MJTN, Vogler APet al., 2015, Phylogenetic community ecology of soil biodiversity using mitochondrial metagenomics, MOLECULAR ECOLOGY, Vol: 24, Pages: 3603-3617, ISSN: 0962-1083 Baselga A, Gomez-Rodriguez C, Vogler AP, 2015, Multi-hierarchical macroecology at species and genetic levels to discern neutral and non-neutral processes, GLOBAL ECOLOGY AND BIOGEOGRAPHY, Vol: 24, Pages: 873-882, ISSN: 1466-822X Crampton-Platt A, Timmermans MJTN, Gimmel ML, Kutty SN, Cockerill TD, Khen CV, Vogler APet al., 2015, Soup to Tree: The Phylogeny of Beetles Inferred by Mitochondrial Metagenomics of a Bornean Rainforest Sample, MOLECULAR BIOLOGY AND EVOLUTION, Vol: 32, Pages: 2302-2316, ISSN: 0737-4038