Sena, Giovanni - Imperial College London - Department of Life Sciences, Biology, Ecology and Environmental Biology, Microbiology, Zoology

个人简介

My background is in theoretical physics and developmental biology. If I had to pick a generic label for my main research interest, that would be quantitative developmental biology. I am broadly interested in physical and genetic mechanisms generating “growth and form” in multicellular systems, especially through the establishment and maintenance of spatio-temporal patterns within a field of interacting cells. I believe that plants offer many experimental advantages that make them attractive model systems to address fundamental questions on multi-cellular organization. Arabidopsis thaliana is the model system of choice in my lab, and the preferred approach is a combination of genetics, quantitative imaging and mathematical modeling. In essence, I view organisms' development as a process of self-organization and morphogenesis as one of its emergent properties.

近期论文

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Kral N, Hanna Ougolnikova A, Sena G, 2016, Externally imposed electric field enhances plant root tip regeneration., Regeneration (Oxf), Vol: 3, Pages: 156-167 Sena G, Garcia L, 2016, SPECIMEN MOUNTING DEVICE AND METHOD FOR LIVE MICROSCOPY Sena G, 2014, Stem Cells and Regeneration in Plants, NEPHRON EXPERIMENTAL NEPHROLOGY, Vol: 126, Pages: 35-39, ISSN: 1660-2129 Sena G, Frentz Z, Birnbaum KD, Leibler Set al., 2011, Quantitation of Cellular Dynamics in Growing Arabidopsis Roots with Light Sheet Microscopy, PLOS ONE, Vol: 6, ISSN: 1932-6203 Sena G, Birnbaum KD, 2010, Built to rebuild: in search of organizing principles in plant regeneration, CURRENT OPINION IN GENETICS & DEVELOPMENT, Vol: 20, Pages: 460-465, ISSN: 0959-437X Sena G, Wang X, Liu H-Y, Hofhuis H, Birnbaum KDet al., 2009, Organ regeneration does not require a functional stem cell niche in plants, NATURE, Vol: 457, Pages: 1150-U110, ISSN: 0028-0836 Sena G, Jung JW, Benfey PN, 2004, A broad competence to respond to SHORT ROOT revealed by tissue-specific ectopic expression, DEVELOPMENT, Vol: 131, Pages: 2817-2826, ISSN: 0950-1991 Benfey PN, Gallagher K, Paquette A, Nakajima K, Sena Get al., 2003, Radial patterning in arabidopsis: A moving target, 62nd Annual Meeting of the Society-for-Development-Biology, Pages: 523-523, ISSN: 0012-1606 Sena G, Nakajima K, Jung J, Benfey PNet al., 2002, Analysis of Arabidopsis root pattern formation: Tissue-specific ectopic expression of the "Moving" putative transcription factor short-root., Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: 486-487, ISSN: 0012-1606 Benfey PN, Nakajima K, Sena G, Paquette Aet al., 2001, Radial patterning in Arabidopsis: Signaling inside out., Publisher: ACADEMIC PRESS INC, Pages: 288-288, ISSN: 0012-1606 Nakajima K, Sena G, Nawy T, Benfey PNet al., 2001, Intercellular movement of the putative transcription factor SHR in root patterning, NATURE, Vol: 413, Pages: 307-311, ISSN: 0028-0836 Helariutta Y, Fukaki H, Wysocka-Diller J, Nakajima K, Jung J, Sena G, Hauser MT, Benfey PNet al., 2000, The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling, CELL, Vol: 101, Pages: 555-567, ISSN: 0092-8674 Sena G, Onado C, Cappella P, Montalenti F, Ubezio Pet al., 1999, Measuring the complexity of cell cycle arrest and killing of drugs: Kinetics of phase-specific effects induced by Taxol, Cytometry, Vol: 37, Pages: 113-124, ISSN: 0196-4763 Montalenti F, Sena G, Cappella P, Ubezio Pet al., 1998, Simulating cancer-cell kinetics after drug treatment: Application to cisplatin on ovarian carcinoma, Physical Review E, Vol: 57, Pages: 5877-5887, ISSN: 1063-651X