个人简介
学习经历
2017/06-2013/08 中山大学 生物无机化学 博士
2015/12-2017/01 美国圣约翰大学生物技术学院 联合培养
2010/08-2013/06 湘潭大学 硕士
工作经历
2019/08-至今 中山七院 副研究员
2019/07-2017/07 深圳大学医学部博士后
研究领域
(1)肿瘤诊疗探针;(2)肿瘤多药耐药逆转;(3)临床样本处理与大数据分析
近期论文
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Jia Li1, Leli Zeng1*, Zheng Wang, Hengxing Chen, Shuo Fang, Jinquan Wang, Chao-Yun Cai, Enming Xing, Xinxing Liao, Zhi-Wei Li, Charles R. Ashby Jr, Zhe-Sheng Chen*, Hui Chao*,Yihang Pan*. Cycloruthenated Self-Assembly with Metabolic Inhibition to Efficiently Overcome Multidrug Resistance in Cancers. Advanced Materials (IF:30.849),2022,34 (1), 2100245.
Yuzhi Xu, Si-Yang Liu, Yanfei Zhang, Hansu Ma, Huihui Yang, Yuchen Liu, Shuo Fang, Jing Zhao, Yunsheng Xu, Leli Zeng,* Zong Dai,* and Yihang Pan*. A Polymer as Drug Barrier against Systemic Toxicity for Cancer Starvation and Photodynamic Synergistic Therapy. Advanced Materials,2022 (under review).
Zhuo-Xun Wu, Yuqi Yang, Jing-Quan Wang, Silpa Narayanan, Zi-Ning Lei, Qiu-Xu Teng, Leli Zeng*, Zhe-Sheng Chen*, “Overexpression of ABCG2 confers resistance to MLN7243, a ubiquitin-activating enzyme (UAE) inhibitor”, Frontiers in cell and developmental biology (IF: 6.684), 2021, 9, 1727.
Leli Zeng, Kai Huang, Yilin Wan, Jing Zhang, Xikuang Yao, Chao Jiang, Jing Lin & Peng Huang*. “Programmable starving-photodynamic synergistic cancer therapy”. Science China Materials (IF: 8.273), 2020, 63, 611-619.
Leli Zeng, Pranav Gupta, Yanglu Chen, Enju Wang, Liangnian Ji, Hui Chao* and Zhe-Sheng Chen*, “The development of anticancer ruthenium(II) complexes: from single molecule compounds to nanomaterials”, Chemical Society Reviews (IF: 54.564), 2017, 46, 5771-5804.
Leli Zeng1, Gongcheng Ma1 (co-first author), Jing Lin, and Peng Huang*, “Photoacoustic probes for molecular detection: recent advances and perspectives”, Small (IF:13.281), 2018, 14, 1800782.
Leli Zeng1, Gongcheng Ma1 (co-first author), Han Xu, Jing Mu, Fan Li, Xiaoting Gao, Zhuoting Deng, Junle Qu, Peng Huang and Jing Lin*, “In vivo chemoselective photoacoustic imaging of copper(II) in plant and animal subjects”, Small (IF:13.281), 2019, 15, 1803866.
Leli Zeng1, Shi Kuang1 (co-first author), Guanying Li, Chengzhi Jin, Liangnian Ji and Hui Chao*, “A GSH-activatable ruthenium(II)-azo photosensitizer for two-photon photodynamic therapy”, Chemical Communications (IF:6.222), 2017, 53, 1977-1980.
Leli Zeng1, Jia Li1 (co-first author), Chen Zhang, Yun-Kai Zhang, Wei Zhang, Juanjuan Huang, Charles R. Ashby Jr, Liangnian Ji, Zhe-Sheng Chen* and Hui Chao*, “An organoruthenium complex overcomes ABCG2-mediated multidrug resistance via multiple mechanisms”. Chemical Communications (IF:6.222), 2019, 55, 3833-3836.
Leli Zeng1, Yanyan Yuan1 (co-first author), Chao Jiang, Jing Mu, Fan Li, Yilin Wan, Han Xu, Junle Qu, Peng Huang and Jing Lin*, “A near-infrared turn-on probe for in vivo chemoselective photoacoustic detection of fluoride ions”, Dyes and Pigments (IF:4.889), 2019, 155, 408-414.