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个人简介

中山医科大学临床医学专业学士,美国路易斯安那州立大学医学中心细胞生物学博士、康奈尔大学医学院博士后、美国医学遗传学学院临床Fellow。曾就职于康奈尔大学医学院附属医院病理科6年,从事基因检测、诊断的临床工作。有中美两国的临床实践及医学研究工作经历近30年,在解读与疾病和健康相关的遗传学因素方面有丰富的临床经验。作为一名资深精准医学领域的科学家,潘逸航博士带领其课题组团队致力于精准医学研究。在Advanced Materials、Nature Neuroscience、Gut、Signal Transduction and Targeted Therapy等国际期刊发表高水平论文30余篇,出版一本医学专业书章节,并担任多个SCI杂志审稿人,主持或参与10余项国家级科研项目,是国家重点研发计划合成生物学专项课题《膀胱癌致病相关基因回路及相互作用网络的机制研究》的课题组组长。担任广东省临床医学会临床规范化培训与管理专委会副主任委员、深圳市医学会人工智能机器人专业委员会副主任委员等。

研究领域

潘逸航课题组主要致力于精准医学研究,重点方向是肿瘤学和神经科学。主要是在人类基因的层面上寻找疾病的早期诊断标志物、治疗靶点及基因变异在疾病发生、发展机制的研究,并开展诊断试剂及治疗药物和治疗方案的研究。

近期论文

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Jia Li#, Leli Zeng#*, Zheng Wang, Hengxing Chen, Shuo Fang, Jinquan Wang, Chao-Yun Cai, Enming Xing, Xinxing Liao, Zhi-Wei Li, Charles R. Ashby Jr, Zhe-Sheng Chen*, Hui Chao*, Yihang Pan*. Cycloruthenated Self-Assembly with Metabolic Inhibition to Efficiently Overcome Multidrug Resistance in Cancers. Advanced Materials, 2022 Jan, 34(1), 2100245. (IF= 30.849,一区) Qiangsheng He#, Man Yang, Xiwen Qin, Die Fan, Jinqiu Yuan*, Yihang Pan*. Risk stratification for proton pump inhibitor-associated type 2 diabetes: a population-based cohort study. Gut, 2021 Nov, 70(11), 2212-2213. (IF=23.059,一区) Qiangsheng He# , Bin Xia#, Wenbo Meng#, Die Fan, Zi-Chong Kuo, Junjie Huang, Xiwen Qin, Huachun Zou, Yulong He, Changhua Zhang, Shuo Fang, Yihang Pan*, Man Yang*, Jinqiu Yuan*. No Associations Between Regular Use of Proton Pump Inhibitors and Risk of All-Cause and Cause-Specific Mortality: A Population-Based Cohort of 0.44 Million Participants. The American Journal of Gastroenterology, 2021 Nov, 116(11), 2286-2291. (IF=10.864,一区) Man Yang#, Qiangsheng He#, Fang Gao, Krish Nirantharakumar, Tonny Veenith, Xiwen Qin, Amy T Page, Martin C S Wong, Junjie Huang, Zi Chong Kuo, Bin Xia, Changhua Zhang, Yulong He, Wenbo Meng*, Jinqiu Yuan*, Yihang Pan*. Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials. BMC Medicine, 2021 Dec, 19(1), 316.12. (IF=8.775,一区) Yuzhi Xu#, Yanfei Zhang, Huihui Yang, Wen Yin, Leli Zeng, Shuo Fang, Si-Yang Liu*, Zong Dai*, Xiaoyong Zou, Yihang Pan*, Two-dimensional coordination polymer-based nanosensor for sensitive and reliable nucleic acids detection in living cells. Chinese Chemical Letters, 2021 July, doi.org/10.1016/j.cclet.2021.07.041. (In press). (IF= 6.779,二区) Silpa Narayanan#, Zhuo-Xun Wu#, Jing-Quan Wang#, Hansu Ma, Nikita Acharekar, Jagadish Koya, Sabesan Yoganathan, Shuo Fang*, Zhe-Sheng Chen*, Yihang Pan*. The Spleen Tyrosine Kinase Inhibitor, Entospletinib (GS-9973) Restores Chemosensitivity in Lung Cancer Cells by Modulating ABCG2-mediated Multidrug Resistance. International Journal of Biological Sciences, 2021 Jun, 17(10), 2652-2665. (IF=6.58,二区) Zhuo-Xun Wu#, Qiuyan Mai#, Yuqi Yang, Jing-Quan Wang, Hansu Ma, Leli Zeng, Zhe-Sheng Chen*, Yihang Pan*. Overexpression of human ATP-binding cassette transporter ABCG2 contributes to reducing the cytotoxicity of GSK1070916 in cancer cells. Biomedicine & Pharmacotherapy, 2021 Apr, 136, 111223. (IF=6.529,二区) Changbo Qu#, Gwenny M Fuhler*, Yihang Pan*. Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19? International Journal of Molecular Sciences, 2021 May, 22(11), 5672. (IF= 5.923,二区) Bin Xia#, Jianjun Peng, De Toni Enrico, Kuiqing Lu, Eddie C Cheung, Zichong Kuo, Qiangsheng He, Yan Tang, Anran Liu, Die Fan, Changhua Zhang, Yulong He*, Yihang Pan*, Jinqiu Yuan*. Metabolic syndrome and its component traits present gender-specific association with liver cancer risk: a prospective cohort study. BMC Cancer, 2021 Oct, 21(1), 1084. (IF=4.430,二区) Changbo Qu#, Jaap Keijer, Merel J W Adjobo-Hermans, Melissa van de Wal, Tom Schirris, Clara van Karnebeek, Yihang Pan*, Werner J H Koopman*. The ketogenic diet as a therapeutic intervention strategy in mitochondrial disease. The International Journal of Biochemistry & Cell Biology. 2021 Sep, 138, 106050. (IF=5.085,三区) Jun Ju#, Xiuyan Yang#, Jian Jiang#, Dilong Wang , Yumeng Zhang , Xiaofeng Zhao , Xiaoyi Fang , Huanquan Liao , Lei Zheng , Shupeng Li , Sheng-Tao Hou , Liyang Liang, Yihang Pan*, Huiliang Li*, Ningning Li*. Structural and Lipidomic Alterations of Striatal Myelin in 16p11.2 Deletion Mouse Model of Autism Spectrum Disorder. Frontiers in Cellular Neuroscience, 2021 Aug, 15, 718720. (IF=5.505,二区) Lang You#, Fengxia Li#, Yan Sun#, Liang Luo, Jian Qin, Tao Wang, Yuchen Liu, Ruogu Lai, Ruohan Li, Xiaoran Guo, Qiuyan Mai, Yihang Pan*, Jianrong Xu*, Ningning Li*. Extract of Acalypha australis L. inhibits lipid accumulation and ameliorates HFD-induced obesity in mice through regulating adipose differentiation by decreasing PPARγ and CEBP/α expression. Food & Nutrition Research, 2021 Mar, 65. (IF=3.894,二区) Jinqiu Yuan#, Yanhong Jessika Hu, Jie Zheng, Jean Hee Kim, Tim Sumerlin, Youpeng Chen, Yulong He, Changhua Zhang, Jinling Tang, Yihang Pan*, Michael Moore*. Long-term use of antibiotics and risk of type 2 diabetes in women: a prospective cohort study. International Journal of Epidemiology, 2020 Oct, 49(5), 1572-1581. (IF=7.196, 一区) Yihang Pan#, Meiqi Xin#, Changhua Zhang#, Willa Dong, Yuan Fang, Wenhui Wu, Mingzhe Li, Jun Pang, Zilong Zheng, Zixin Wang#*, Jinqiu Yuan#, Yulong He#. Associations of Mental Health and Personal Preventive Measure Compliance With Exposure to COVID-19 Information During Work Resumption Following the COVID-19 Outbreak in China: Cross-Sectional Survey Study. Journal of Medical Internet Research, 2020 Oct, 22(10), e22596. (IF=5.428, 二区) Yihang Pan#, Yuan Fang#, Meiqi Xin, Willa Dong, Liemin Zhou, Qinghua Hou, Fanping Li, Gang Sun, Zilong Zheng, Jinqiu Yuan#, Zixin Wang#, Yulong He#*. Self-Reported Compliance With Personal Preventive Measures Among Chinese Factory Workers at the Beginning of Work Resumption Following the COVID-19 Outbreak: Cross-Sectional Survey Study. Journal of Medical Internet Research, 2020 Sep, 22(9), e22457.(IF=5.428, 二区) Jinqiu Yuan#, Changhua Zhang#, Jeffrey A Sparks, Susan Malspeis , Kelvin Kam-Fai Tsoi , Jean H Kim , Benjamin A Fisher , Fang Gao , Tim Sumerlin , Yan Liu , Yuxing Liu , Yihang Pan*, Yulong He*, Joseph J Y Sung. Regular use of proton pump inhibitor and risk of rheumatoid arthritis in women: a prospective cohort study. Alimentary Pharmacology & Therapeutics, 2020 Aug, 52(3), 449-458. (IF=8.171, 一区) Yun Chen#, Yao Guo#, Yihang Pan*, Zhizhuang Joe Zhao*. Structure analysis of the receptor binding of 2019-nCoV. Biochemical and Biophysical Research Communications, 2020 Feb, 525(1), 135–40.(IF=3.575, 三区) Bin Xia#, Qiang-Sheng He#, Yihang Pan#, Fang Gao, An-Ran Liu, Yan Tang, Charing Chong, Anthony Y. B. Teoh, Fang-Ping Li, Yulong He*, Changhua Zhang*, Jin-Qiu Yuan*. Metabolic syndrome and risk of pancreatic cancer: A population-based prospective cohort study. International Journal of Cancer, 2020 Dec, 147(12), 3384-3393. (IF=7.396, 一区) Dilong Wang#, Qiuyan Mai#, Xiuyan Yang#, Xinjin Chi, Ruohan Li, Jian Jiang, Liang Luo, Xiaoyi Fang, Peng Yun, Liyang Liang, Guang Yang, Kun Song, Liang Fang, Yun Chen, Ying Zhang, Yulong He, Ningning Li*, Yihang Pan. Microduplication of 16p11.2 locus Potentiates Hypertrophic Obesity in Association with Imbalanced Triglyceride Metabolism in White Adipose Tissue. Molecular Nutrition & Food Research, 2022 Jan, 2100241. (IF=5.914,二区) Hanna Foster#, E Josue Ruiz#, Christopher Moore, Gordon W H Stamp, Emma L Nye, Ningning Li, Yihang Pan, Yulong He, Julian Downward, Axel Behrens*. ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma. Cancer Research, 2019 Oct, 79(20), 5159-5166. (IF=12.701,二区)

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