Kazarian, Sergei - Imperial College London - Department of Chemical Engineering

个人简介

2006- Professor of Physical Chemistry 2006-2011 Director of Postgraduate Studies, Chemical Engineering Department, Imperial College London 2004-2006 Reader in Physical Chemistry 2001-2004 Lecturer, Chemical Engineering Department, Imperial College London 1998-2000 Research Fellow, Research Associate, Chemical Engineering Department, Imperial College London 1994-1998 Research Scientist II, Research Associate, School of Chemical Engineering, Georgia Institute of Technology, Atlanta, USA 1991-1994 University Research Fellow, Chemistry Department, University of Nottingham, UK

研究领域

My principal research interests are advanced vibrational spectroscopy, molecular interactions and materials processing. I develop FTIR spectroscopic chemical imaging methods and apply them to materials characterisation, pharmaceuticals, drug delivery, biomedical samples, microfluidics, high-throughput analysis of dynamic systems, nanostructured materials, forensic science and the analysis of objects of cultural heritage. My research interests also include applications of Raman spectroscopy to polymeric and biomedical materials, including depth profiling with confocal Raman microscopy and nanoscale imaging with tip-enhanced Raman spectroscopy. My current research interests include spectroscopic imaging of live cancer cells and tissues for advancing healthcare diagnostics; I also collaborate closely with neurosurgeons at the Charing Cross Hospital as well as participate in the activities of CLIRSPEC. My research publications can be found at the tab above, or on Google Scholar.

近期论文

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Sroka-Bartnicka A, Borkowski L, Ginalska G, Ślósarczyk A, Kazarian SGet al., 2017, Structural transformation of synthetic hydroxyapatite under simulated in vivo conditions studied with ATR-FTIR spectroscopic imaging., Spectrochim Acta A Mol Biomol Spectrosc, Vol: 171, Pages: 155-161 Boulet-Audet M, Kazarian SG, Byrne B, 2016, In-column ATR-FTIR spectroscopy to monitor affinity chromatography purification of monoclonal antibodies, Scientific Reports, Vol: 6, ISSN: 2045-2322 Chan KLA, Kazarian SG, 2016, Attenuated total reflection Fourier-transform infrared (ATR-FTIR) imaging of tissues and live cells, CHEMICAL SOCIETY REVIEWS, Vol: 45, Pages: 1850-1864, ISSN: 0306-0012 Ewing AV, Clarke GS, Kazarian SG, 2016, Attenuated total reflection-Fourier transform infrared spectroscopic imaging of pharmaceuticals in microfluidic devices, BIOMICROFLUIDICS, Vol: 10, ISSN: 1932-1058 Gabrienko AA, Ewing AV, Chibiryaev AM, Agafontsev AM, Dubkov KA, Kazarian SGet al., 2016, New insights into the mechanism of interaction between CO2 and polymers from thermodynamic parameters obtained by in situ ATR-FTIR spectroscopy, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol: 18, Pages: 6465-6475, ISSN: 1463-9076 Gabrienko AA, Martyanov ON, Kazarian SG, 2016, Behavior of Asphaltenes in Crude Oil at High-Pressure CO2 Conditions: In Situ Attenuated Total Reflection-Fourier Transform Infrared Spectroscopic Imaging Study, ENERGY & FUELS, Vol: 30, Pages: 4750-4757, ISSN: 0887-0624 Hifumi H, Ewing AV, Kazarian SG, 2016, ATR-FTIR spectroscopic imaging to study the drying and dissolution of pharmaceutical polymer-based films., Int J Pharm, Vol: 515, Pages: 57-68 Kimber JA, Foreman L, Turner B, Rich P, Kazarian SGet al., 2016, FTIR spectroscopic imaging and mapping with correcting lenses for studies of biological cells and tissues, FARADAY DISCUSSIONS, Vol: 187, Pages: 69-85, ISSN: 1359-6640 Muginova SV, Myasnikova DA, Kazarian SG, Shekhovtsova TNet al., 2016, Evaluation of novel applications of cellulose hydrogel films reconstituted from acetate and chloride of 1-butyl-3-methylimidazolium by comparing their optical, mechanical, and adsorption properties, Materials Today Communications, Vol: 8, Pages: 108-117 Prati S, Milosevic M, Sciutto G, Bonacini I, Kazarian SG, Mazzeo Ret al., 2016, Analyses of trace amounts of dyes with a new enhanced sensitivity FTIR spectroscopic technique: MU-ATR (metal underlayer ATR spectroscopy)., Anal Chim Acta, Vol: 941, Pages: 67-79 Punčochová K, Ewing AV, Gajdošová M, Pekárek T, Beránek J, Kazarian SG, Štěpánek Fet al., 2016, The Combined Use of Imaging Approaches to Assess Drug Release from Multicomponent Solid Dispersions., Pharm Res Shinzawa H, Mizukado J, Kazarian SG, 2016, Fourier Transform Infrared (FT-IR) Spectroscopic Imaging Analysis of Partially Miscible PMMA-PEG Blends Using Two-Dimensional Disrelation Mapping., Appl Spectrosc Taylor JD, Hawthorne WJ, Lo J, Dear A, Jain N, Meisl G, Andreasen M, Fletcher C, Koch M, Darvill N, Scull N, Escalera-Maurer A, Sefer L, Wenman R, Lambert S, Jean J, Xu Y, Turner B, Kazarian SG, Chapman MR, Bubeck D, de Simone A, Knowles TPJ, Matthews SJet al., 2016, Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones, SCIENTIFIC REPORTS, Vol: 6, ISSN: 2045-2322 Boulet-Audet M, Byrne B, Kazarian SG, 2015, Cleaning-in-place of immunoaffinity resins monitored by in situ ATR-FTIR spectroscopy, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol: 407, Pages: 7111-7122, ISSN: 1618-2642 Dattani R, Gibson KF, Few S, Borg AJ, DiMaggio PA, Nelson J, Kazarian SG, Cabral JTet al., 2015, Fullerene oxidation and clustering in solution induced by light, JOURNAL OF COLLOID AND INTERFACE SCIENCE, Vol: 446, Pages: 24-30, ISSN: 0021-9797 Ewing AV, Biggart GD, Hale CR, Clarke GS, Kazarian SGet al., 2015, Comparison of pharmaceutical formulations: ATR-FTIR spectroscopic imaging to study drug-carrier interactions, INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol: 495, Pages: 112-121, ISSN: 0378-5173 Ewing AV, Gabrienko AA, Semikolenov SV, Dubkov KA, Kazarian SGet al., 2015, How Do Intermolecular Interactions Affect Swelling of Polyketones with a Differing Number of Carbonyl Groups? An In Situ ATR-FTIR Spectroscopic Study of CO2 Sorption in Polymers, JOURNAL OF PHYSICAL CHEMISTRY C, Vol: 119, Pages: 431-440, ISSN: 1932-7447 Ewing AV, Wray PS, Clarke GS, Kazarian SGet al., 2015, Evaluating drug delivery with salt formation: Drug disproportionation studied in situ by ATR-FTIR imaging and Raman mapping, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, Vol: 111, Pages: 248-256, ISSN: 0731-7085 Foreman L, Kimber JA, Oliver KV, Brown JM, Janes SM, Fearn T, Kazarian SG, Rich Pet al., 2015, Assessing Dysplasia of a Bronchial Biopsy with FTIR Spectroscopic Imaging, Conference on Optical Diagnostics and Sensing XV - Toward Point-of-Care Diagnostics, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X Gabrienko AA, Martyanov ON, Kazarian SG, 2015, Effect of Temperature and Composition on the Stability of Crude Oil Blends Studied with Chemical Imaging in Situ, ENERGY & FUELS, Vol: 29, Pages: 7114-7123, ISSN: 0887-0624