Heng, Jerry - Imperial College London - Department of Chemical Engineering

个人简介

2011- Senior Lecturer, Department of Chemical Engineering, Imperial College London, UK 2007-2011 Lecturer, Department of Chemical Engineering, Imperial College London, UK 2006 Research Associate, Department of Chemical Engineering, Imperial College London, UK 2002-2006 PhD in Chemical Engineering, "Anisotropic Surface Properties of Crystalline Pharmaceutical Solids" Department of Chemical Engineering, Imperial College London, UK 1998-2002 B.Eng (Hons), Department of Chemical Engineering, Universiti Teknologi Malaysia, Malaysia

研究领域

My principal area of research is to develop an improved fundamental understanding of the role of surface properties in particle engineering. Research activities include; i) studying the impact of particle engineering unit operations on surface properties (eg. crystallisation, milling); (ii) effects of particle properties on unit operations (eg granuation, drying); (iii) to employ modeling tools for the predictions and control of these operations; and (iv) the development of a gas chromatographic characterisation (inverse gas chromatography, IGC) methodology to determine surface energetic of powders. The key hypothesis here is that the interface may be very important in governing a range of interactions occurring at the solid-solid, solid-liquid, solid-vapour phases. Knowledge of surface properties and particle properties (eg. shape, size, porosity) can lead to the engineering of optimised particles for improved formulation and product performance including better powder processing and particle handling. Other areas of our research interests include: 1. Wetting, contact angles and surface energetics; 2. Physico-chemical properties characterisation of solids; and 3. Processing (milling, spray/freeze-drying) of organic solids (pharmaceuticals and proteins).

近期论文

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Al Nasser WN, Shah VV, Nikiforou K, Petrou P, Heng JYYet al., 2016, Effect of silica nanoparticles to prevent calcium carbonate scaling using an in situ turbidimetre, CHEMICAL ENGINEERING RESEARCH & DESIGN, Vol: 110, Pages: 98-107, ISSN: 0263-8762 Biegaj K, Kwek JW, Lukas T, Rowland M, Heng JYYet al., 2016, Novel Coupling of a Capacitive Probe with a Dynamic Vapor Sorption (DVS) Instrument for the Electrostatic Measurements of Powders, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, Vol: 55, Pages: 5585-5589, ISSN: 0888-5885 Hedberg SHM, Heng JYY, Williams DR, Liddell JMet al., 2016, Micro scale self-interaction chromatography of proteins: A mAb case-study, JOURNAL OF CHROMATOGRAPHY A, Vol: 1434, Pages: 57-63, ISSN: 0021-9673 Lapidot T, Campbell KLS, Heng JYY, 2016, Model for Interpreting Surface Crystallization Using Quartz Crystal Microbalance: Theory and Experiments, ANALYTICAL CHEMISTRY, Vol: 88, Pages: 4886-4893, ISSN: 0003-2700 Smith RR, Shah UV, Parambil JV, Burnett DJ, Thielmann F, Heng JYet al., 2016, The Effect of Polymorphism on Surface Energetics of D-Mannitol Polymorphs., AAPS J Yao Z, Heng JYY, Lanceros-Mendez S, Pegoretti A, Ji X, Hadjittofis E, Xia M, Wu W, Tang Jet al., 2016, Study on the surface properties of colored talc filler (CTF) and mechanical performance of CTF/acrylonitrile-butadiene-styrene composite, JOURNAL OF ALLOYS AND COMPOUNDS, Vol: 676, Pages: 513-520, ISSN: 0925-8388 Yao Z, Wu D, Tang J, Wu W, Heng JYY, Zhao Het al., 2016, A novel colored talc filler: Preparation and surface property determination using two distinct methods, CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, Vol: 155, Pages: 54-61, ISSN: 0169-7439 Cai X, Yang H, Heng JYY, 2015, Preface, POWDER TECHNOLOGY, Vol: 282, Pages: 1-1, ISSN: 0032-5910 Hedberg S, Heng JYY, Williams DR, Liddell Jet al., 2015, Chromatographic tools to predict the stability of mAbs for faster identification of therapeutic candidates, Pages: 1150-1151 Hedberg SHM, Heng JYY, Williams DR, Liddell JMet al., 2015, Self-Interaction Chromatography of mAbs: Accurate Measurement of Dead Volumes, PHARMACEUTICAL RESEARCH, Vol: 32, Pages: 3975-3985, ISSN: 0724-8741 Parambil JV, Poornachary SK, Hinder SJ, Tan RBH, Heng JYYet al., 2015, Establishing template-induced polymorphic domains for API crystallisation: the case of carbamazepine, CRYSTENGCOMM, Vol: 17, Pages: 6384-6392, ISSN: 1466-8033 Shah UV, Amberg C, Diao Y, Yang Z, Heng JYYet al., 2015, Heterogeneous nucleants for crystallogenesis and bioseparation, CURRENT OPINION IN CHEMICAL ENGINEERING, Vol: 8, Pages: 69-75, ISSN: 2211-3398 Shah UV, Olusanmi D, Narang AS, Hussain MA, Tobyn MJ, Hinder SJ, Heng JYYet al., 2015, Decoupling the Contribution of Surface Energy and Surface Area on the Cohesion of Pharmaceutical Powders, PHARMACEUTICAL RESEARCH, Vol: 32, Pages: 248-259, ISSN: 0724-8741 Shah UV, Parambil JV, Williams DR, Hinder SJ, Heng JYYet al., 2015, Preparation and characterisation of 3D nanotemplates for protein crystallisation, POWDER TECHNOLOGY, Vol: 282, Pages: 10-18, ISSN: 0032-5910 Shah UV, Wang Z, Olusanmi D, Narang AS, Hussain MA, Tobyn MJ, Heng JYYet al., 2015, Effect of milling temperatures on surface area, surface energy and cohesion of pharmaceutical powders, INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol: 495, Pages: 234-240, ISSN: 0378-5173 Spathi C, Young N, Heng JYY, Vandeperre LJM, Cheeseman CRet al., 2015, A simple method for preparing super-hydrophobic powder from paper sludge ash, MATERIALS LETTERS, Vol: 142, Pages: 80-83, ISSN: 0167-577X Wang D, Da Z, Zhang B, Isbell MA, Dong Y, Zhou X, Liu H, Heng JYY, Yang Zet al., 2015, Stability study of tubular DNA origami in the presence of protein crystallisation buffer, RSC ADVANCES, Vol: 5, Pages: 58734-58737, ISSN: 2046-2069 Wang Z, Shah UV, Olusanmi D, Narang AS, Hussain MA, Gamble JF, Tobyn MJ, Heng JYYet al., 2015, Measuring the sticking of mefenamic acid powders on stainless steel surface, INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol: 496, Pages: 407-413, ISSN: 0378-5173 Cai X, Heng J, 2014, Particle Science and Engineering, Publisher: Royal Society of Chemistry, ISBN: 9781849739573