Overby, Darryl - Imperial College London - Department of Bioengineering

个人简介

Darryl Overby earned his Ph.D. in Mechanical Engineering in 2002 from the Massachusetts Institute of Technology under the supervision of Dr. Mark Johnson and Prof. Roger Kamm for research on the mechanism of intraocular pressure regulation in relation to glaucoma. He spent 3 years as a post-doctoral research fellow at Harvard Medical School and Children’s Hospital Boston working under Prof. Donald Ingber in the area of cellular biomechanics and mechanotransduction in relation to vascular biology. Between October 2004 and June 2008, he served as Assistant Professor in the Department of Biomedical Engineering at Tulane University. He joined the academic staff at Imperial in July 2008.

近期论文

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Braakman ST, Moore JE, Ethier CR, Overby DRet al., 2016, Transport across Schlemm's canal endothelium and the blood-aqueous barrier, EXPERIMENTAL EYE RESEARCH, Vol: 146, Pages: 17-21, ISSN: 0014-4835 Dismuke WM, Overby DR, Civan MM, Stamer WDet al., 2016, The Value of Mouse Models for Glaucoma Drug Discovery., J Ocul Pharmacol Ther, Vol: 32, Pages: 486-487 Johnson M, McLaren JW, Overby DR, 2016, Unconventional aqueous humor outflow: A review., Exp Eye Res Li G, Mukherjee D, Navarro I, Ashpole NE, Sherwood JM, Chang J, Overby DR, Yuan F, Gonzalez P, Kopczynski CC, Farsiu S, Stamer WDet al., 2016, Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 787, Pages: 20-31, ISSN: 0014-2999 Martella A, Silvestri C, Maradonna F, Gioacchini G, Allara M, Radaelli G, Overby DR, Di Marzo V, Carnevali Oet al., 2016, Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop, ENDOCRINOLOGY, Vol: 157, Pages: 1751-1763, ISSN: 0013-7227 Sherwood JM, Reina-Torres E, Bertrand JA, Rowe B, Overby DRet al., 2016, Measurement of Outflow Facility Using iPerfusion, PLOS ONE, Vol: 11, ISSN: 1932-6203 Boussommier-Calleja A, Li G, Wilson A, Ziskind T, Scinteie OE, Ashpole NE, Sherwood JM, Farsiu S, Challa P, Gonzalez P, Downs JC, Ethier CR, Stamer WD, Overby DRet al., 2015, Physical Factors Affecting Outflow Facility Measurements in Mice, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol: 56, Pages: 8331-8339, ISSN: 0146-0404 Braakman ST, Read AT, Chan DW-H, Ethier CR, Overby DRet al., 2015, Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal, EXPERIMENTAL EYE RESEARCH, Vol: 130, Pages: 87-96, ISSN: 0014-4835 Chang JYH, Braakman ST, Mohri Z, Weinberg P, Ethier CR, Stamer WD, Overby DRet al., 2015, Colocalization of segmental outflow and endogenous eNOS activity in the conventional outflow pathway of mice, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 Chang JYH, Stamer WD, Bertrand J, Read AT, Marando CM, Ethier CR, Overby DRet al., 2015, Role of nitric oxide in murine conventional outflow physiology, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, Vol: 309, Pages: C205-C214, ISSN: 0363-6143 Overby DR, Clark AF, 2015, Animal models of glucocorticoid-induced glaucoma, EXPERIMENTAL EYE RESEARCH, Vol: 141, Pages: 15-22, ISSN: 0014-4835 Overby DR, Reina-Torres E, Wen JC, Liu K, Li G, Sherwood JM, Allingham RR, Stamer WDet al., 2015, The Effects of VEGF and anti-VEGF on Outflow Facility in Mice and Humans, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 Reina-Torres E, Herrnberger L, Sherwood JM, Tamm ER, Overby DRet al., 2015, The Influence of Plasmalemma Vesicle-Associated Protein on Conventional Outflow Facility in Mice, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 Schwaner SA, Sherwood JM, Snider E, Geisert EE, Overby DR, Ethier CRet al., 2015, Ocular Compliance in Mice, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 Stamer WD, Braakman ST, Zhou EH, Ethier CR, Fredberg JJ, Overby DR, Johnson Met al., 2015, Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction, PROGRESS IN RETINAL AND EYE RESEARCH, Vol: 44, Pages: 86-98, ISSN: 1350-9462 Amin HD, Brady MA, St-Pierre J-P, Stevens MM, Overby DR, Ethier CRet al., 2014, Stimulation of Chondrogenic Differentiation of Adult Human Bone Marrow-Derived Stromal Cells by a Moderate-Strength Static Magnetic Field, TISSUE ENGINEERING PART A, Vol: 20, Pages: 1612-1620, ISSN: 1937-3341 Ashpole NE, Overby DR, Ethier CR, Stamer WDet al., 2014, Shear Stress-Triggered Nitric Oxide Release From Schlemm's Canal Cells, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol: 55, Pages: 8067-8076, ISSN: 0146-0404 Braakman ST, Pedrigi RM, Read AT, Smith JAE, Stamer WD, Ethier CR, Overby DRet al., 2014, Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells, EXPERIMENTAL EYE RESEARCH, Vol: 127, Pages: 224-235, ISSN: 0014-4835 Brady MA, Vaze R, Amin HD, Overby DR, Ethier CRet al., 2014, The Design and Development of a High-Throughput Magneto-Mechanostimulation Device for Cartilage Tissue Engineering, TISSUE ENGINEERING PART C-METHODS, Vol: 20, Pages: 149-159, ISSN: 1937-3384 Chang JYH, Folz SJ, Laryea SN, Overby DRet al., 2014, Multi-Scale Analysis of Segmental Outflow Patterns in Human Trabecular Meshwork with Changing Intraocular Pressure, JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, Vol: 30, Pages: 213-223, ISSN: 1080-7683