Krapp, Holger - Imperial College London - Department of Bioengineering

个人简介

Holger G Krapp obtained his Diploma in Biology (Neurobiology) from the University of Tübingen, Germany, in 1992. In 1995 he was awarded the Dr rer nat (PhD) degree for studying the neuronal mechanisms of optic flow processing at the Max-Planck Institute for Biological Cybernetics, Tübingen, Germany. During his first postdoctoral position at the Max-Planck Institute for Biological Cybernetics he continued working on theoretical aspects and the neuronal basis of self-motion estimation. In 1996 he became postdoctoral scholar at the California Institute of Technology, Pasadena, USA, working on the biophysical mechanism of neuronal multiplication in the context of visually guided behaviour. From 1997 he spent three years as a research fellow at Bielefeld University, Germany, continuing his work on adaptations to optic flow processing in the visual system. In 2000 he commenced a position as a temporary lecturer in Sensory Neuroscience in the Department of Zoology, University of Cambridge, UK, investigating fundamental principles underlying the sensory control of behaviour. He was appointed as a senior lecturer in the Department of Bioengineering at Imperial College in October 2005.

研究领域

Research in my lab aims at understanding biological design principles in sensorimotor control. We pursue an integrative approach on comparatively simple insect model systems to discover fundamental principles of task-specific sensory integration, multisensor fusion, and sensorimotor transformation. The range of methods applied in the lab includes electrophysiological techniques, quantitative behavioural measurements, and computational modeling. More recently I became particularly interested in interdisciplinary collaborations to exploit the potential of biological principles for the engineering design of artificial sensorimotor control systems. My lab at Imperial College and partly together with my national as well as international collaborators we work on research topics including: Design, adaptability, and plasticity of sensorimotor transformations in flying insects. The neural basis of optic flow processing and self-motion estimation for inner-loop reflexes such as gaze stabilization and flight control in insects. State-dependent processing of sensory information in flying insects. Dynamic range fractioning of multisensory control in insects. Forward models (efference copy) in fly motor control. The neuronal mechanisms underlying collision avoidance and escape behaviour in locusts. The development of new micro-recording probes to set up brain-machine interfaces.

近期论文

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Hardcastle B, Schwyn DA, Bierig K, Krapp HGet al., 2016, Integration of Multiple Visual Inputs in the Blowfly, PERCEPTION, Vol: 45, Pages: 700-701, ISSN: 0301-0066 Huang JV, Krapp HG, 2015, Closed-Loop Control in an Autonomous Bio-hybrid Robot System Based on Binocular Neuronal Input, 4th International Conference on Biomimetic and Biohybrid Systems (Living Machines), Publisher: SPRINGER-VERLAG BERLIN, Pages: 164-174, ISSN: 0302-9743 Krapp HG, 2015, How a fly escapes the reflex trap, NATURE NEUROSCIENCE, Vol: 18, Pages: 1192-1194, ISSN: 1097-6256 Mokso R, Schwyn DA, Walker SM, Doube M, Wicklein M, Mueller T, Stampanoni M, Taylor GK, Krapp HGet al., 2015, Four-dimensional in vivo X-ray microscopy with projection-guided gating, SCIENTIFIC REPORTS, Vol: 5, ISSN: 2045-2322 Gremillion G, Humbert JS, Krapp HG, 2014, Bio-inspired modeling and implementation of the ocelli visual system of flying insects, BIOLOGICAL CYBERNETICS, Vol: 108, Pages: 735-746, ISSN: 0340-1200 Krapp HG, 2014, Sensory Integration: Neuronal Filters for Polarized Light Patterns, CURRENT BIOLOGY, Vol: 24, Pages: R840-R841, ISSN: 0960-9822 Longden KD, Muzzu T, Cook DJ, Schultz SR, Krapp HGet al., 2014, Nutritional State Modulates the Neural Processing of Visual Motion, CURRENT BIOLOGY, Vol: 24, Pages: 890-895, ISSN: 0960-9822 Sabatier Q, Krapp HG, Tanaka RJ, 2014, Dynamic optimisation for fly gaze stabilisation based on noisy and delayed sensor information, 13th European Control Conference (ECC), Publisher: IEEE, Pages: 1783-1788 Walker SM, Schwyn DA, Mokso R, Wicklein M, Mueller T, Doube M, Stampanoni M, Krapp HG, Taylor GKet al., 2014, In Vivo Time- Resolved Microtomography Reveals the Mechanics of the Blowfly Flight Motor, PLOS BIOLOGY, Vol: 12, ISSN: 1545-7885 Ejaz N, Krapp HG, Tanaka RJ, 2013, Closed-loop response properties of a visual interneuron involved in fly optomotor control, FRONTIERS IN NEURAL CIRCUITS, Vol: 7, ISSN: 1662-5110 Mokso R, Marone F, Irvine S, Nyvlt M, Schwyn D, Mader K, Taylor GK, Krapp HG, Skeren M, Stampanoni Met al., 2013, Advantages of phase retrieval for fast x-ray tomographic microscopy, JOURNAL OF PHYSICS D-APPLIED PHYSICS, Vol: 46, ISSN: 0022-3727 Yue X, Krapp HG, Drakakis EM, 2013, An output code offset-free comparator for SAR ADCs based on non-linear preamplifier and CMOS inverters, MICROELECTRONICS JOURNAL, Vol: 44, Pages: 414-420, ISSN: 0026-2692 Saleem AB, Longden KD, Schwyn DA, Krapp HG, Schultz SRet al., 2012, Bimodal Optomotor Response to Plaids in Blowflies: Mechanisms of Component Selectivity and Evidence for Pattern Selectivity, JOURNAL OF NEUROSCIENCE, Vol: 32, Pages: 1634-1642, ISSN: 0270-6474 Saleem AB, Longden KD, Schwyn DA, Krapp HG, Schultz SRet al., 2012, Bimodal optomotor response to plaids in blowflies: mechanisms of component selectivity and evidence for pattern selectivity., J Neurosci, Vol: 32, Pages: 1634-1642 Ejaz N, Peterson KD, Krapp HG, 2011, An Experimental Platform to Study the Closed-loop Performance of Brain-machine Interfaces, JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, ISSN: 1940-087X Longden KD, Krapp HG, 2011, Sensory Neurophysiology: Motion Vision during Motor Action, CURRENT BIOLOGY, Vol: 21, Pages: R650-R652, ISSN: 0960-9822 Longden KD, Krapp HG, 2011, Sensory Neurophysiology: Motion Vision during Motor Action (vol 21, pg R650, 2011), CURRENT BIOLOGY, Vol: 21, Pages: 1684-1684, ISSN: 0960-9822 Hyslop A, Krapp HG, Humbert JS, 2010, Control theoretic interpretation of directional motion preferences in optic flow processing interneurons, BIOLOGICAL CYBERNETICS, Vol: 103, Pages: 353-364, ISSN: 0340-1200 Krapp HG, 2010, Sensorimotor Transformation: From Visual Responses to Motor Commands, CURRENT BIOLOGY, Vol: 20, Pages: R236-R239, ISSN: 0960-9822 Longden KD, Krapp HG, 2010, Octopaminergic modulation of temporal frequency coding in an identified optic flow-processing interneuron., Front Syst Neurosci, Vol: 4