Choi, James - Imperial College London - Department of Bioengineering

个人简介

2010 PhD, Biomedical Engineering, Columbia University 2006 MS, Biomedical Engineering, Columbia University 2004 BSE, Computer Engineering, University of Michigan

研究领域

Dr. James J. Choi leads the Noninvasive Surgery & Biopsy Laboratory (www.nsblab.org) and is Lecturer (equivalent to Assistant Professor in the USA) in the Department of Bioengineering at Imperial College London. The research aims of the Noninvasive Surgery & Biopsy Laboratory is to enable physicians to operate on vital organs using incision-less ultrasound-based microsurgical devices and methods. For patients, this implies not only accessible, pain-less, and infection-free techniques, but also potent therapeutic and diagnostic capabilities never achieved before. The laboratory’s current focus is on three research themes:

近期论文

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Pouliopoulos AN, Choi JJ, 2016, Superharmonic microbubble Doppler effect in ultrasound therapy, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 61, Pages: 6154-6171, ISSN: 0031-9155 Coviello C, Kozick R, Choi J, Gyoengy M, Jensen C, Smith PP, Coussios C-Cet al., 2015, Passive acoustic mapping utilizing optimal beamforming in ultrasound therapy monitoring, JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol: 137, Pages: 2573-2585, ISSN: 0001-4966 Koruk H, El Ghamrawy A, Pouliopoulos AN, Choi JJet al., 2015, Acoustic particle palpation for measuring tissue elasticity, APPLIED PHYSICS LETTERS, Vol: 107, ISSN: 0003-6951 Shamout FE, Pouliopoulos AN, Lee P, Bonaccorsi S, Towhidi L, Krams R, Choi JJet al., 2015, ENHANCEMENT OF NON-INVASIVE TRANS-MEMBRANE DRUG DELIVERY USING ULTRASOUND AND MICROBUBBLES DURING PHYSIOLOGICALLY RELEVANT FLOW, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 41, Pages: 2435-2448, ISSN: 0301-5629 Choi JJ, Carlisle RC, Coviello C, Seymour L, Coussios C-Cet al., 2014, Non-invasive and real-time passive acoustic mapping of ultrasound-mediated drug delivery, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 59, Pages: 4861-4877, ISSN: 0031-9155 Graham SM, Carlisle R, Choi JJ, Stevenson M, Shah AR, Myers RS, Fisher K, Peregrino M-B, Seymour L, Coussios CCet al., 2014, Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes, JOURNAL OF CONTROLLED RELEASE, Vol: 178, Pages: 101-107, ISSN: 0168-3659 Pouliopoulos AN, Bonaccorsi S, Choi JJ, 2014, Exploiting flow to control the in vitro spatiotemporal distribution of microbubble-seeded acoustic cavitation activity in ultrasound therapy, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 59, Pages: 6941-6957, ISSN: 0031-9155 Bazan-Peregrino M, Rifai B, Carlisle RC, Choi J, Arvanitis CD, Seymour LW, Coussios CCet al., 2013, Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound, JOURNAL OF CONTROLLED RELEASE, Vol: 169, Pages: 40-47, ISSN: 0168-3659 Carlisle R, Choi J, Bazan-Peregrino M, Laga R, Subr V, Kostka L, Ulbrich K, Coussios C-C, Seymour LWet al., 2013, Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound, JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, Vol: 105, Pages: 1701-1710, ISSN: 0027-8874 Coviello C, Kozick RJ, Choi JJ, Gyöngy M, Collin J, Jensen C, Smith PP, Coussios CCet al., 2013, Passive acoustic mapping using optimal beamforming for real-time monitoring of ultrasound therapy, ISSN: 1939-800X Graham SM, Myers RS, Choi J, Bazan-Peregrino M, Seymour L, Carlisle R, Coussios CCet al., 2013, Use of micro- and nano-sized inertial cavitation nuclei to trigger and map drug release from cavitation-sensitive liposomes. Baseri B, Choi JJ, Deffieux T, Samiotaki G, Tung Y-S, Olumolade O, Small SA, Morrison B, Konofagou EEet al., 2012, Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 57, Pages: N65-N81, ISSN: 0031-9155 Choi JJ, Coussios C-C, 2012, Spatiotemporal evolution of cavitation dynamics exhibited by flowing microbubbles during ultrasound exposure, JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol: 132, Pages: 3538-3549, ISSN: 0001-4966 Konofagou EE, Tung Y-S, Choi J, Deffieux T, Baseri B, Vlachos Fet al., 2012, Ultrasound-Induced Blood-Brain Barrier Opening, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, Vol: 13, Pages: 1332-1345, ISSN: 1389-2010 Carlisle R, Choi J, Kostka L, Bazan-Peregrino M, Ulbrich K, Coussios C, Seymour Let al., 2011, Ultrasound-enhanced delivery of polymer-coated oncolytic adenovirus for tumour growth inhibition, Publisher: MARY ANN LIEBERT INC, Pages: A36-A36, ISSN: 1043-0342 Choi J, Konofagou E, Borden M, 2011, Systems and methods for opening a tissue, US20110295105 A1 Choi JJ, Selert K, Gao Z, Samiotaki G, Baseri B, Konofagou EEet al., 2011, Noninvasive and localized blood-brain barrier disruption using focused ultrasound can be achieved at short pulse lengths and low pulse repetition frequencies, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Vol: 31, Pages: 725-737, ISSN: 0271-678X Choi JJ, Selert K, Vlachos F, Wong A, Konofagou EEet al., 2011, Noninvasive and localized neuronal delivery using short ultrasonic pulses and microbubbles, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 108, Pages: 16539-16544, ISSN: 0027-8424 Baseri B, Choi JJ, Tung Y-S, Konofagou EEet al., 2010, MULTI-MODALITY SAFETY ASSESSMENT OF BLOOD-BRAIN BARRIER OPENING USING FOCUSED ULTRASOUND AND DEFINITY MICROBUBBLES: A SHORT-TERM STUDY, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 36, Pages: 1445-1459, ISSN: 0301-5629 Choi JJ, Feshitan JA, Baseri B, Wang S, Tung Y-S, Borden MA, Konofagou EEet al., 2010, Microbubble-Size Dependence of Focused Ultrasound-Induced Blood-Brain Barrier Opening in Mice In Vivo, IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Vol: 57, Pages: 145-154, ISSN: 0018-9294