Javid, Farideh - Huddersfield University

个人简介

Farideh was offered a Senior Lectureship in Pharmacology at the University of Huddersfield in June 2008. Following her first degree in Chemistry with First Class Honors at the University of Tehran, she then completed an MSc programme in Pharmacology with Distinction at the School of Pharmacy in the University of Bradford. In 1996 she started a PhD research project at the same school in the University of Bradford. Her PhD project was on the neuropharmacological investigation of drugs- and motion-induced emesis and changes in the gastrointestinal motility. Following completion of her PhD studies in 1999, she was employed in various posts at the University of Bradford, including Research Fellow and then Lecturer. During this time she successfully supervised various PhD programmes and also became a Fellow of the Higher Education Academy prior to her move to Huddersfield. She holds several patents as a result of her collaboration with industry. She developed the Pharmacology modules for the MPharm course at the University of Huddersfield for years 1, 2 and 3 and her on-going research programmes focus on identifying and investigating the mechanism of actions of novel drugs in cancer Pharmacology. Her ultimate aim is to develop novel drugs for cancer patients.

研究领域

My research interests focus on how disease processes or abnormalities modify the function of the gastrointestinal tract and also the mechanisms of actions of drugs affecting this system. There is a special interest in establishing the precise involvement and interaction between central and peripheral serotonergic, cannabinoids, neurokinin and other peptidergic systems relevant to significant therapeutic advances in gastrointestinal disorders such as irritable bowel syndrome (IBS) and/or inflammatory bowel disease (IBD). I have also been involved in a research collaboration with the GW Pharmaceuticals to investigate the anti-cancer effects of non-psychoactive cannabinoids on a variety of tumour cells. Further research are under way to also investigate the anti-inflammatory actions of phytocannabinoids and other herbal medicine. In summary my Research Interests are: Gastrointestinal motility E-coli-induced Diarrhoea Development of cell culture models to investigate inflammatory processes and identifying novel anti-inflammatory agents Identifying novel therapeutics with anti-cancer activity Pharmacology of cannabinoids and Herbal Medicine

近期论文

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Kumar, R., Siril, P. and Javid, F. (2016) ‘Unusual anti-leukemia activity of nanoformulated naproxen and other non-steroidal anti-inflammatory drugs’ Materials Science and Engineering: C , 69, pp. 1335-1344. ISSN 0928-4931 Sefat, F., Youseffi, M., Khaghani, S., Soon, C. and Javid, F. (2016) ‘Effect of Transforming Growth Factor-?3 on mono and multilayer chondrocytes’ Cytokine , 83, pp. 118-126. ISSN 1043-4666 Javid, F., Phillips, R., Afshinjavid, S., Verde, R. and Ligresti, A. (2016) ‘Cannabinoid pharmacology in cancer research: A new hope for cancer patients?’ European Journal of Pharmacology . ISSN 0014-2999 Javid, F (2016) ‘Take note Matt LeBlanc: here’s the scientific way to beat car sickness’ The Conversation . ISSN 2044-5032 Hemming, K., Blackburn, J., Molyneux, G., Pitard, A., Rice, C., Page, M., Afshinjavid, S., Javid, F., Coles, S. and Horton, P. (2016) ‘Synthesis, Conformation and Antiproliferative Activity of Isothiazoloisoxazole 1,1-dioxides’ Organic and Biomolecular Chemistry , 14, pp. 2134-2144. ISSN 1477-0539 Makanjuola, S., Ayodele, S., Javid, F., Obafunwa, J., Oludara, M. and Popoola, A. (2014) ‘Breast cancer receptor status assessment and clinicopathological association in Nigerian women: A retrospective analysis’ Journal of Cancer Research & Therapy , 2 (8), pp. 122-127. ISSN 20524994 Mashhadi, F., Naylor, R. and Javid, F. (2014) ‘The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine’ Gene Cell Tissue , 1 (1), p. e18311. ISSN 2345-6833 Javid, F. and Palea, S. (2014) ‘The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus’ European Journal of Pharmacology , 723, pp. 489-493. ISSN 0014-2999 Bolognini, D., Rock, E., Cluny, N., Cascio, M., Limebeer, C., Duncan, M., Stott, C., Javid, F., Parker, L. and Pertwee, R. (2013) ‘Cannabidiolic acid enhances 5-HT1A receptor activation and prevents vomiting in Suncus murinus and nausea-like behaviour in rats with greater potency and selectivity than cannabidiol’ British Journal of Pharmacology , 168 (6), pp. 1456-1470. ISSN 0007-1188 Javid, F., Bulmer, D., Broad, J., Aziz, Q., Dukes, G. and Sanger, G. (2013) ‘Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors’ European Journal of Pharmacology , 699 (1-3), pp. 48-54. ISSN 0014-2999 Afshinjavid, S., Phillips, R. and Javid, F. (2012) ‘The effect of GWP42006, a cannabinoid extract on MCF-7 human breast carcinoma cells’. In: 6th European Congress of Pharmacology (EPHAR 2012), 17th – 20th July 2012, Granada, Spain , p. 496 Afshinjavid, S., Cluny, N., Okeke, I. and Javid, F. (2012) ‘The effect of Enteroaggregative escherichia coli (eaec) on 5-Hydroxytryptamine (5-HT), carbachol and electrical field stimulation (EFS)-induced contraction in the rat ileum’ pA2 Online , 10 (3), p. 350. ISSN 1741-1149 Batista Lobo, S., Denyer, M., Britland, S. and Javid, F. (2011) ‘The Involvement of the Serotonergic Transmission System in Neonatal and Adult Rat Ileum Contractility Varies with Age’ Pharmacology , 88 (3-4), pp. 225-232. ISSN 0031-7012 Cluny, N., Naylor, R., Whittle, B. and Javid, F. (2011) ‘The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus’ Archives of Pharmacal Research , 34 (9), pp. 1509-1517. ISSN 0253-6269 Javid, F., Afshinjavid, S., Phillips, R., Stott, C. and Ayerakwa, L. (2011) ‘The effect of CBD(BDS) botanical cannabinoid extraction on MCF-7 human breast carcinoma cells.’. In: 21st Annual Symposium of the International Cannabinoid Research Society 2011. Pheasant Run, St Charles Illinois, USA: International Cannabinoid Research Society. p. 120. ISBN 978-0-9786040-6-6 Farajian-Mashradi, F., Naylor, R. and Javid, F. (2010) ‘The effect of fluoxetine on electrical field stimulation-induced responses in the isolated rat small intestine’ Methods and Findings in Experimental and Clinical Pharmacology , 32 (9), pp. 645-656. ISSN 0379-0355 Javid, F (2010) ‘The effects of 5-HT and electrical field stimulation (EFS) in the bladder of suncus murinus’. In: WorldPharma, July 17th-22nd, Copenhagen Lobo, S., Denyer, M. and Javid, F. (2010) ‘Intestinal model of Inflammation in primary cells’. In: Inflammation conference, 27-30th January 2010, Luxembourg Soon, C., Youseffi, M., Blagden, N., Lobo, S., Javid, F. and Denyer, M. (2009) ‘Characterisation and biocompatibility study of nematic and cholesteric liquid crystals’. In: Medical Physics and Biomedical Engineering World Congress 2009, Sept 7-12, 2009, Munich, Germany Khaghani, S., Denyer, M., Youseffi, M., Lobo, S. and Javid, F. (2009) ‘Effect of transforming growth factor-beta (TGF-?1) in biological regulation of primary chondrocyte’. In: 15th International Biomedical Science and Technology Symposium, 16 - 19 August 2009, Cyprus