Harburn, J. Jonathan - Durham University - School of Medicine, Pharmacy & Health, Pharmacy

个人简介

Jonathan Harburn carried out his PhD with Professor Brian Marples at Loughborough University (1994-1998).

研究领域

Drug design and synthesis Nano magnetic theranostics Fragment based drug design Microfluidic systems Molecular modelling Antimicrobial drugs

近期论文

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Tefft, B.J, Gooden J.Y, Uthamaraj, S Harburn, J.J, Klabusay, M, Holmes, D.R, Simari, R.D, Dragomir-Daescu, D & Sandhu, G.S (2013). Magnetizable duplex steel stents enable endothelial cell capture. IEEE Transactions on Magnetics 49(1): 463-466. Kottakota, S.K, Evangelopoulos, D, Alnimr, A, Bhakta, S, McHugh, T.D, Gray, M, Groundwater, P.W, Marrs, E.C.L, Perry, J.D, Spilling, C.D & Harburn, J.J (2012). Synthesis and Biological Evaluation of Purpurealidin E-Derived Marine Sponge Metabolites: Aplysamine-2, Aplyzanzine A, Suberedamines A and B. Journal of Natural Products 75(6): 1090-1101. Kottakota, S.K, Benton, M, Evangelopoulos, D, Guzman, J.D, Bhakta, S, McHugh, T.D, Gray, M, Groundwater, P.W, Marrs, E.C.L, Perry, J.D & Harburn, J.J (2012). Versatile Routes to Marine Sponge Metabolites through Benzylidene Rhodanines. Organic Letters 14(24): 6310-6313 Gray, M & Harburn, J.J (2011). Dynamic Covalent Chemistry in Fragment-based Drug Design. Encyclopedia of Supramolecular Chemistry 1-9. Brook, C.E, Harris, W.R, Spilling, C.D, Peng, W, Harburn, J.J & Srisung, S (2005). Effect of Ligand Structure on the Pathways for Iron Release from Serum Transferrin. Inorganic Chemistry 44(14): 5183-5191. Harburn, J.J, Rath, N.P & Spilling, C.D (2005). Efficient Synthesis of Tyrosine-Derived Marine Sponge Metabolites via Acylation of Amines with a Coumarin. Journal of Organic Chemistry 70(16): 6398–6403. Harris, L.A, Goff, J.D, Carmichael, A.Y, Riffle, J.S, Harburn, J.J, St. Pierre, T.G & Saunders, M (2003). Magnetite Nanoparticle Dispersions Stabilized with Triblock Copolymers. Chemistry of Materials 15(6): 1367-1377. Boehlow, T.R, Harburn, J.J & Spilling, C.D (2001). Approaches to the Synthesis of Some Tyrosine-Derived Marine Sponge Metabolites: Synthesis of Verongamine and Purealdin N. Journal of Organic Chemistry 66(9): 3111-3118. Harburn, J.J, Loftus, G.C & Marples, B.A (1998). Steroid A-Ring Aromatisation of C-Ring Substituted 1,4-dien-3-ones. Journal of Chemical Research 8: 424-425. Harburn, J.J, Loftus, G.C & Marples, B.A (1998). Synthesis of Novel Steroidal Inhibitors of HIV-1 Protease. Tetrahedron 54(39): 11907-11924.