近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Angell, R.M, Angell, T.D, Bamborough, P, Bamford, M.J, Chung, C-W, Cockerill, G.S, Flack, S.S, Jones, K.L, Laine, D.I, Longstaff, T, Ludbrook, S, Pearson, R, Smith, K.J, Smee, P.A, Somers, D.O & Walker, A.L (2008). Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes. Bioorganic & Medicinal Chemistry Letters 18(15): 4433-4437.
Henderson, EA, Alber, DG, Baxter, RC, Bithell, SK, Budworth, J, Carter, MC, Chubb, A, Cockerill, GS, Dowdell, VCL, Fraser, IJ, Harris, RA, Keegan, S, Kelsey, RD, Lumley, JA, Stables, JN, Weerasekera, N Wilson, LJ & Powell, KL (2007). 1,4-Benzodiazepines as Inhibitors of Respiratory Syncytial Virus. The Identification of a Clinical Candidate. Journal of Medicinal Chemistry 50(7): 1685-1692.
Chapman, J, Abbott, E, Alber, DG Baxter, RC Bithell, SK Henderson, EA Carter, MC Chambers, P Chubb, A Cockerill, GS, Collins, PL, Dowdell, VCL Keegan, SJ Kelsey, RD, Lockyer, MJ, Luongo, C, Najarro, P, Pickles, RJ, Simmonds, M Taylor, D, Tyms, S, Wilson, L.J & Powell, K.L (2007). RSV604, a novel inhibitor of respiratory syncytial virus replication. Antimicrobial Agents and Chemotherapy 51(9): 3346-3353.
Carter, M.C., Alber, D.G., Baxter, R.C. Bithell, S.K., Budworth, J., Chubb, A., Cockerill, G.S., Dowdell, V.C.L., Henderson, E.A., Keegan, S.J., Kelsey, R.D., Lockyer, M.J., Stables, J.N., Wilson, L.J. & Powell, K.L. (2006). 1,4-Benzodiazepines as inhibitors of respiratory syncytial virus. Journal of Medicinal Chemistry 49(7): 2311-2319.
Petrov, KG, Zhang, YM, Carter, M, Cockerill, GS, Dickerson, S, Gauthier, CA, Guo, U, Mook, RA, Rusnak, DW, Walker, AL, Wood, ER & Lackey, KE (2006). Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series. Bioorganic and Medicinal Chemistry Letters 16(17): 4686-4691.
Zhang, YM, Cockerill, GS, Guntrip, SB, Rusnak, D, Smith, K, Vanderwall, D, Wood, E & Lackey, K (2004). Synthesis and SAR of potent EGFR/erbB2 dual inhibitors. Bioorganic and Medicinal Chemistry Letters 14(1): 111-114.
Gaul, MD, Guo, Y, Affleck, K, Cockerill, GS, Gilmer, TM, Griffin, RJ, Guntrip, S, Keith, BR, Knight, WB, Mullin, RJ, Murray, DM, Rusnak, DW, Smith, K, Tadepali, S, Wood, ER & Lackey, K (2003). Discovery and biological evaluation of potent dual ErbB-2/EGFR tyrosine kinase inhibitors: 6-thiazolylquinazolines. Bioorganic and Medicinal Chemistry Letters 4: 637-640.
Cockerill, GS & Karen, EL (2002). Small molecule inhibitors of the class 1 receptor tyrosine kinase family. Current Topics in Medicinal Chemistry 2: 999-1008.
Cockerill, GS, Stubberfield, C, Stables, J, Carter, M, Guntrip, S, Smith, K, McKeown, S, Shaw, R, Topley, P, Thomsen, L, Affleck, K, Jowett, A, Hayes, D, Willson, M, Woollard, P & Spalding, D (2001). Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2. Bioorganic and Medicinal Chemistry Letters 11: 1401-1405.
Slater, MJ, Baxter, R, Bonser, RW, Cockerill, GS, Gohil, K, Parry, N, Robinson, E, Randall, R, Yeates, C, Snowden, W & Walters, A (2001). Synthesis of N-Alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication. Bioorganic and Medicinal Chemistry Letters 11(15): 1993-1995.
Rusnak, D.W., Affleck, K., Cockerill, G.S., Stubberfield, C., Harris, R., Page, M, Smith, K.J., Guntrip, S.B., Carter, M.C., Shaw, R.J., Jowett, A., Stables, J., Topley, P., Wood, ER, Brignola, PS, Kadwell, S.H, Reep, B.R., Mullin, R.J., Alligood, K.J., Keith, B.R., Crosby, R.M., Murray, D.M., Knight, W.B., Gilmer, T.M. & Lackey, K. (2001). The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Research 61(19): 7196-7203.
Cockerill, GS, Easterfield, HJ, Percy, JM & Pintat, S (2000). Facile syntheses of building blocks for the construction of phosphotyrosine mimetics. Journal of the Chemical Society, Perkin Transactions 1 16: 2591-2599.
Cockerill, GS, Easterfield,, Howard, J & Percy, JM (1999). Facile syntheses of aryldifluorophosphonate bulding blocks. Tetrahedron Letters 40(13): 2601-2604.
Slater, MJ, Cockerill,GS, Baxter, R, Bonser, RW, Gohil, K, Gowrie, C, Robinson, JE, Littler, E, Parry, N, Randall, R & Snowden, W (1999). Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication. Bioorganic and Medicinal Chemistry 7(6): 067-1074.
Blades, K, Butt, AH, Cockerill, GS, Easterfield HJ, Lequeux, TP & Percy, JM (1999). Synthesis of activated alkenes bearing the difluoromethylenephosphonate group: a range of building blocks for the synthesis of secondary difluorophosphonates. Journal of the Chemical Society (3609-3614).
Blades, K, Cockerill, GS, Easterfield, HJ, Lequeux, TP & Percy, JM (1996). A DAST-free route to aryl(difluoromethyl)phosphonic esters. Chemical Communications 14: 1615-1616.
Ashton, DS, Beddell, CR, Cockerill, SG, Gohil, K, Gowrie, C, Robinson, JW, Slater, MJ & Valko, KJ (1996). Binding measurements of indolocarbazole derivatives to immobilized human serum albumin by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 667(1): 194-198.
Cockerill, SG, Levett, PC & Whiting, DA (1995). Synthesis of novel inhibitors of electron transport. Journal of the Chemical Society, Perkin Transactions 1 9: 1103-1113.
Levett, PC, Whiting, DA, Cayley, J, Cockerill, SG & Weston, JB (1994). Structural requirements for respiratory inhibition by rotenoids; is an intact B/C ring system essential?. Bioorganic and Medicinal Chemistry Letters 4(3): 505-508.
Ahmad-Junan, SA, Amos, PC, Cockerill, SG, Levett, PC & Whiting, DA (1994). Synthetic studies on electron transport inhibitors related to natural products. Biochemical Society Transactions 22(1): 237-241.
Mortimore, M, Cockerill, GS, Kocienski, P & Treadgold, R (1987). A synthesis of pseudo-Gloesporone. Tetrahedron Letters 28(32): 3747-3750.
Cockerill, GS, Kocienski, P & Treadgold, R (1985). Silicon-mediated annulation. Part 1. A synthesis of tetrahydropyran-4-ones, oxepan-4-ones, and oxocan-4-ones via intramolecular directed aldol reactions. Journal of the Chemical Society, Perkin Transactions 1 10: 2093-2100.
Cockerill, GS, Kocienski, P & Treadgold, R (1985). Silicon-mediated annulation. Part 2. A synthesis of b-alkoxy cyclooctanones via intramolecular directed aldol reactions. Journal of the Chemical Society, Perkin Transactions 1 10: 2101-2108.
Cockerill, GS & Kocienski, P (1983). Observations on the scope of an intramolecular directed aldol condensation. A new synthesis of eight-membered rings. Journal of the Chemical Society, Chemical Communications 12: 705-106.