Sandford, Graham - Durham University - Department of Chemistry

研究领域

Organofluorine Chemistry Continuous Flow Processes

近期论文

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Heeran, D. & Sandford, G. (2016). Fluorination of pyrrole derivatives by Selectfluor?. Tetrahedron 72(19): 2456-2463. Abraham, F., Ford, W.E., Scholz, F., Nelles, G., Sandford, G. & von Wrochem, F. (2016). Surface Energy and Work Function Control of AlOx/ Al Surfaces by Fluorinated Benzylphosphonic Acids. ACS Applied Materials & Interfaces 8(18): 11857-11867. Willis, N.J., Fisher, C.A., Alder, C.M., Harsanyi, A., Shukla, L., Adams, J.P. & Sandford, G. (2016). Sustainable synthesis of enantiopure fluorolactam derivatives by a selective direct fluorination – amidase strategy. Green Chemistry 18(5): 1313-1318. Sato, K., Sandford, G., Shimizu, K., Akiyama, S., Lancashire, M.J., Yufit, D.S., Tarui, A., Omote, M., Kumadaki, I., Harusawa, S. & Ando, A. (2016). Synthesis of fluorinated isoxazoles using SelectfluorTM: preparation and characterization of 4-fluoroisoxazole, 4,4,5-trifluoroisoxazoline and 4,4-difluoro-5-hydroxyisoxazoline systems from one-pot and multi-step processes. Tetrahedron 72(13): 1690-1698. Gadsby, J.M., McPake, C.B., Murray, C.B. & Sandford, G. (2016). Synthesis of polyfluorinated terphenyl and styrene derivatives by palladium catalysed C-F bond activation of polyfluoronitroaromatic substrates. Journal of Fluorine Chemistry 181: 51-55. Harsanyi, A. & Sandford, G. (2015). Fluorine gas for life science syntheses: green metrics to assess selective direct fluorination for the synthesis of 2-fluoromalonate esters. Green Chemistry 17(5): 3000-3009. Harsanyi, A. & Sandford, G. (2015). Organofluorine Chemistry: Applications, sources and sustainability. Green Chemistry 17(4): 2081-2086. Breen, J.R., Sandford, G., Patel, B. & Fray, J. (2015). Synthesis of 4,4-difluoro-1H-pyrazole derivatives. Synlett 26(01): 51-54. Harsanyi, A. & Sandford, G. (2014). 2-Fluoromalonate esters: fluoroaliphatic building blocks for the life sciences. Organic Process Research & Development 18(8): 981-992. Fisher, C.A., Harsanyi, A., Sandford, G., Yufit, D.S. & Howard, J.A.K. (2014). Fluorotetrahydroquinolines from diethyl 2-fluoromalonate ester. CHIMIA 68(6): 425-429. Sandford, G., Slater, R., Yufit, D.S., Howard, J.A.K. & Vong, A. (2014). Pyrido[3,2-b][1,4]oxazine and pyrido[2,3-b][1,4]benzoxazine systems from tetrafluoropyridine derivatives. Journal of Fluorine Chemistry 167: 91-95. Harsanyi, A., Sandford, G., Yufit, D.S. & Howard, J.A.K. (2014). Syntheses of fluoro-oxindole and 2-fluoro-2-arylacetic acid derivatives from diethyl 2-fluoromalonate ester. Beilstein Journal of Organic Chemistry 10: 1213-1219. Shaughnessy, MJ, Harsanyi, A, Li, J, Bright, T, Murphy, CD & Sandford, G (2014). Targeted fluorination of a nonsteroidal anti-inflammatory drug to prolong metabolic half-life. ChemMedChem 9(4): 733-–736. Fox, M.A., Pattison, G., Sandford, G. & Batsanov, A.S. (2013). 19F and 13C GIAO-NMR chemical shifts for the identification of perfluoro-quinoline and -isoquinoline derivatives. Journal of Fluorine Chemistry 155: 62-71. Bright, TV, Dalton, F., Elder, V.L., Murphy, C.D., O’Connor, N.K. & Sandford, G. (2013). A convenient chemical-microbial method for developing fluorinated pharmaceuticals. Organic & Biomolecular Chemistry 11(7): 1135-1142. McPake, C.B., Murray, C.B. & Sandford, G. (2013). Continuous flow synthesis of difluoroamine systems by direct fluorination. Australian Journal of Chemistry 66(2): 145-150. Sandford, G. (2013). Efficient Preparations of Fluorine Compounds. Edited by Herbert W. Roesky. ChemMedChem 8(8): 1417. Cargill, M.R., Sandford, G., Kilickiran, P. & Nelles, G. (2013). Pd-catalysed sp2-sp cross-coupling reactions involving aromatic C-F bond activation in highly fluorinated nitrobenzene systems. Tetrahedron 69(2): 512-516. Hudson, A., Hoose, A., Sandford, G. & Cobb, S.L. (2013). Synthesis of a novel tetra-fluoropyridine containing amino acid and tripeptide. Tetrahedron Letters 54(36): 4865-4867.