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Flow Synthesis Organic Chemistry Synthetic Chemistry

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Mallia, C. J., Burton, P. M., Smith, A. M. R., Walter, G. C. & Baxendale, I. R. (2016). Catalytic Chan–Lam coupling using a ‘tube-in-tube’ reactor to deliver molecular oxygen as an oxidant. Beilstein Journal of Organic Chemistry 12: 1598-1607. Baumann, M. & Baxendale, Ian R. (2016). Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement. Reaction Chemistry & Engineering 1(2): 147-150. Baumann, Marcus & Baxendale, Ian R. (2016). Continuous-Flow Synthesis of 2H-Azirines and Their Diastereoselective Transformation to Aziridines. SynLett 27(01): 159-163. Filipponi, Paolo, Gioiello, Antimo & Baxendale, Ian R. (2016). Controlled Flow Precipitation as a Valuable Tool for Synthesis. Organic Process Research & Development 20(2): 371-375. Parker, G. L., Smith, L. K. & Baxendale, I. R. (2016). Development of the industrial synthesis of vitamin A. Tetrahedron 72(13): 1645-1652. Hu, T., Baxendale, I. R. & Baumann, M. (2016). Exploring Flow Procedures for Diazonium Formation. Molecules 21(7): 918. Mallia, C. J., Walter, G. C. & Baxendale, I. R. (2016). Flow carbonylation of sterically hindered ortho-substituted iodoarenes. Beilstein Journal of Organic Chemistry 12: 1503-1511. Holmes, Nicholas, Akien, Geoffrey R., Savage, Robert J. D., Stanetty, Christian, Baxendale, Ian R., Blacker, A. John, Taylor, Brian A., Woodward, Robert L., Meadowse, Rebecca E. & Bourne, Richard A. (2016). Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors. Reaction Chemistry & Engineering 1(1): 96-100. Filipponi, P. & Baxendale, I. R. (2016). The Generation of a Library of -Bromodomain-Containing Protein Modulators Expedited by Continuous Flow Synthesis. European Journal of Organic Chemistry 2016(11): 2000-2012. Mallia, C. J. & Baxendale, I. R. (2016). The Use of Gases in Flow Synthesis. Organic Process Research & Development 20(2): 327-360. Rojo, M. V., Guetzoyan, L. & Baxendale, I. R. (2015). A monolith immobilised iridium Cp* catalyst for hydrogen transfer reactions under flow conditions. Organic & Biomolecular Chemistry 13(6): 1768-1777. Baxendale, I. R. (2015). A Short Multi-step Flow Synthesis of a Potential Spirocyclic Fragrance Component. Chemical Engineering and Technology 38(10): 1713-1716. Baxendale, I. R., Braatz, R. D., Hodnett, B. K., Jensen, K. F., Johnson, M. D., Sharratt, P., Sherlock J.-P. & Florence, A. J. (2015). Achieving Continuous Manufacturing: Technologies and Approaches for Synthesis, Workup, and Isolation of Drug Substance. Journal of Pharmaceutical Sciences 104(3): 781-791. Baumann, B. & Baxendale, I. R. (2015). Batch and Flow Synthesis of Pyrrolo[1,2-a]-quinolines via an Allene-Based Reaction Cascade. The Journal of Organic Chemistry 80(21): 10806-10816. Christodoulou, M. S., Calogero, F., Baumann, M., García-Argáez, A. N., Pieraccini, S., Sironi, M., Dapiaggi, F., Bucci, R., Broggini, G., Gazzola, S., Liekens, S., Silvani, A., Lahtela-Kakkonen, M., Martinet, N., Nonel-Canals, A., Santamaría-Navarroh, E., Baxendale, I. R., Via, L. D. & Passarell, D. (2015). Boehmeriasin A as new lead compound for the inhibition of Topoisomerases and SIRT2. European Journal of Medicinal Chemistry 92: 766-775. Mallia, C. J., Englert, L., Walter, G. C. & Baxendale, I. R. (2015). Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate. Molbank 2015(2): M857. Baumann, M., Rodriguez Garcia, A. M. & Baxendale, I. R. (2015). Flow Synthesis of Ethyl Isocyanoacetate Enabling the Telescoped Synthesis of 1,2,4-Triazoles and Pyrrolo-[1,2-c]pyrimidines. Organic & Biomolecular Chemistry 14(13): 4231-4239. Stanetty, C. & Baxendale, I. R. (2015). Large-Scale Synthesis of Crystalline 1,2,3,4,6,7-Hexa-O-acetyl-L-glycero-α-D-manno-heptopyranose. European Journal of Organic Chemistry 2015(12): 2718-2726. Baumann, M. & Baxendale, I. R. (2015). Syn-Ethyl 1-hydroxy-7-methoxy-2,3-dihydro-1H-pyrrolo[3,4-b]quinolone-3-carboxylate HCl Salt. Molbank 2015(1): M846. Teppo Olavi Leino, Marcus Baumann, Jari Yli-Kauhaluoma, Ian R. Baxendale & Erik Aarne Anders Wallén (2015). Synthesis of 1,3,6-Trisubstituted Azulenes. The Journal of Organic Chemistry 80(22): 11513–11520.

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