Przyborski, Stefan - Durham University - School of Biological and Biomedical Science

研究领域

Developmental Neuroscience Stem cell biology Tissue engineering

近期论文

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Ciechomska, M., O'Reilly, S., Przyborski, S., Oakley, F., Bogunia-Kubik, K. & van Laar, J.M. (2016). Histone demethylation and TLR8-dependent crosstalk in monocytes promotes trans-differentiation of fibroblasts in systemic sclerosis via Fra2. Arthritis & Rheumatology 68(6): 1493-1504. O’Reilly, S., Ciechomska, M., Fullard, N., Przyborski, S. & van Laar, J.M. (2016). IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics. Scientific Reports 6: 25066 Collin, J., Mellough, C.B., Dorgau, B., Przyborski, S., Moreno-Gimeno, I. & Lako, M. (2016). Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation. STEM CELLS 34(2): 311-321. Hill, D.S., Robinson, N.D.P., Caley, M.P., Chen, M., O'Toole, E.A., Armstrong, J.L., Przyborski, S. & Lovat, P.E. (2015). A novel fully-humanised 3D skin equivalent to model early melanoma invasion. Molecular Cancer Therapeutics 14(11): 2665-2673. Knight, Eleanor & Przyborski, Stefan (2015). Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro. Journal of Anatomy 227(6): 746-756. Johnson, D.W., Langford, C.R., Didsbury, M.P., Lipp, B., Przyborski, S.A. & Cameron, N.R. (2015). Fully biodegradable and biocompatible emulsion template polymer scaffolds by thiol-acrylate polymerisation of polycaprolactone macropolymers. Polymer Chemistry 6(41): 7256-7263. Smith, I., Haag, M., Ugbode, C., Tams, D., Rattray, M., Przyborski, S., Bithell, A. & Whalley, B.J. (2015). Neuronal-glial populations form functional networks in a biocompatible 3D scaffold. Neuroscience Letters 609: 198-202. Jiang, Y., Habibollah, S., Tilgner, K., Collin, J., Barta, T., Al-Aama, J.Y., Tesarov, L., Hussain, R., Trafford, A.W., Kirkwood, G., Sernagor, E., Eleftheriou, C.G., Przyborski, S., Stojkovi?, M., Lako, M., Keavney, B. & Armstrong, L. (2014). An induced pluripotent stem cell model of hypoplastic left heart syndrome (HLHS) reveals multiple expression and functional differences in HLHS-derived cardiac myocytes. Stem Cells Translational Medicine 3(4): 416-423 Lopez-Real, R.E., Budge, J.J.R., Marder, T.B., Whiting, A., Hunt, P.N & Przyborski, S.A. (2014). Application of Synthetic Photostable Retinoids Induces Novel Limb and Facial Phenotypes During Chick Embryogenesis In Vivo. Journal of Anatomy 224(4): 392-411. Tilgner, K., Neganova, I., Moreno-Gimeno, I., Al-Aama, J.Y., Burks, D., Yung, S., Singhapol, C., Saretzki, G., Evans, J., Gorbunova, V., Gennery, A., Przyborski, S., Stojkovic, M., Armstrong, L., Jeggo, P. & Lako, M. (2013). A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors. Cell Death and Differentiation 20(8): 1089-1100. Moad, M., Pal, D., Hepburn, A.C., Williamson, S.C., Wilson, L., Lako, M., Armstrong, L., Hayward, S.W., Franco, O.E., Cates, J.M., Fordham, S.E., Przyborski, S., Carr-Wilkinson, J., Robson, C.N. & Heer, R. (2013). A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. European Urology 64(5): 753-761. Hayward, A.S., Sano, N., Przyborski, S.A. & Cameron, N.R. (2013). Acrylic-acid-functionalized PolyHIPE scaffolds for use in 3D cell culture. Macromolecular Rapid Communications 34(23-24): 1844-1849. Tilgner, K, Neganova, I, Singhapol, C, Saretzki, G, Al-Aama, JY, Evans, J, Gorbunova, V, Gennery, A, Przyborski, S, Stojkovic, M, Armstrong, L, Jeggo, P & Lako, M (2013). Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors. Stem cells 31(9): 2015-2023. Yung, SK, Tilgner, K, Ledran, MH, Habibollah, S, Neganova, I, Singhapol, C, Saretzki, G, Stojkovic, M, Armstrong, L, Przyborski, S & Lako M. (2013). Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors. Stem cells 31(5): 1022-1029. Clemens, G., Flower, K.R., Gardner, P., Henderson, A. P., Knowles, J. P., Marder, T. B., Whiting, A. & Przyborski, S. A. (2013). Design and biological evaluation of synthetic retinoids: Probing length vs. stability vs. activity. Molecular BioSystems 9(12): 3124-3134. Hayward, A.S., Eissa, A.M., Maltman, D.J., Przyborski, S.A. & Cameron, N.R. (2013). Galactose-Functionalized PolyHIPE Scaffolds for Use in Routine Three Dimensional Culture of Mammalian Hepatocytes. Biomacromolecules 14(12): 4271–4277. Ljujic, B., Milovanovic, M., Volarevic, V., Murray, B., Bugarski, D., Przyborski, S., Arsenijevic, N., Lukic, M.L. & Stojkovic, M. (2013). Human mesenchymal stem cells creating an immunosuppressive environment and promote breast cancer in mice. Scientific Reports 3: 2298. Godoy, P., Hewitt, N.J., Albrecht, U., Andersen, M.E., Ansari, N., Bhattacharya, S., Bode, J.G., Bolleyn, J., Borner, C., B?ttger, J., Braeuning, A., Budinsky, R.A., Burkhardt, B., Cameron, N.R., Camussi, G., Cho, C.S., Choi, Y.J., Craig, Rowlands J., Dahmen, U., Damm, G., Dirsch, O., Donato, M.T., Dong, J., Dooley, S., Drasdo, D., Eakins, R., Ferreira, K.S., Fonsato, V., Fraczek, J., Gebhardt, R., Gibson, A., Glanemann, M., Goldring, C.E., Gómez-Lechón, M.J., Groothuis, G.M., Gustavsson, L., Guyot, C., Hallifax, D., Hammad, S., Hayward, A., H?ussinger, D., Hellerbrand, C., Hewitt, P., Hoehme, S., Holzhütter, H.G., Houston, J.B., Hrach, J., Ito, K., Jaeschke, H., Keitel, V., Kelm, J.M., Kevin Park, B., Kordes, C., Kullak-Ublick, G.A., LeCluyse, E.L., Lu, P., Luebke-Wheeler, J., Lutz, A., Maltman, D.J., Matz-Soja, M., McMullen, P., Merfort, I., Messner, S., Meyer, C., Mwinyi, J., Naisbitt, D.J., Nussler, A.K., Olinga, P., Pampaloni, F., Pi, J., Pluta, L., Przyborski, S.A., Ramachandran, A., Rogiers, V., Rowe, C., Schelcher, C., Schmich, K., Schwarz, M., Singh, B., Stelzer, E.H., Stieger, B., St?ber, R., Sugiyama, Y., Tetta, C., Thasler, W.E., Vanhaecke, T., Vinken, M., Weiss, T.S., Widera, A., Woods, C.G., Xu, J.J., Yarborough, K.M. & Hengstler, J.G. (2013). Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87(8): 1315-1530. Zhou, G.-L., Tams, D. M., Marder, T. B., Valentine, R., Whiting, A. & Przyborski, S. A. (2013). Synthesis and applications of 2,4-disubstituted thiazoles derivatives as small molecule modulators of cellular development. Organic & Biomolecular Chemistry 11(14): 2323-2334. Clemens, G., Flower, K. R., Henderson, A. P., Whiting, A., Przyborski, S. A., Jimenez-Hernandez, M., Ball, F., Bassan, P., Cinque, G. & Gardner, P. (2013). The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Molecular BioSystems 9(4): 677-692.