Jahoda, CAB - Durham University - School of Biological and Biomedical Science

研究领域

Adult Hair Growth and Skin Wound Healing - Regeneration and the Production of In Vitro Skin Models and Skin Replacement Epithelial-Mesenchymal Interactions in the Development and Growth of Skin and Integumental Appendages Hair Follicle Mesenchymal Progenitor Cells Human Hair Follicle Induction: Application to Transplantation Technology Transdifferentiation of Epithelial Stem Cells

近期论文

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Mardaryev, A.N., Liu, B., Rapisarda, V., Poterlowicz, K., Malashchuk, I., Rudolf, J., Sharov, A.A., Jahoda, C.A., Fessing, M.Y., Benitah, S.A., Xu, G.-L. & Botchkarev, V.A. (2016). Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. The Journal of Cell Biology 212(1): 77-89. Jahoda, Colin & Gilmore, Adam (2016). What Lies Beneath: Wnt/β-Catenin Signaling and Cell Fate in the Lower Dermis. Journal of Investigative Dermatology 136(6): 1084-1087. Higgins, C.A., Chen, J.C., Cerise, J.E., Jahoda, C.A.B. & Christiano, A.M. (2013). Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth. Proceedings of the National Academy of Sciences of the USA 110(49): 19679–19688. Higgins, CA, Westgate, GE & Jahoda, CA. (2011). Modulation in proteolytic activity is identified as a hallmark of exogen by transcriptional profiling of hair follicles. Journal of Investigative Dermatology 131: 2349-2357. Petukhova, L., Duvic, M. Hordinsky, M. Norris, D. Price, V. Shimomura, Y. Kim, H. Singh, P. Lee, A. Chen, W.V. Meyer, K.C. Paus, R. Jahoda, C.A., Amos, C.I. Gregersen, P.K. & Christiano, A.M. (2010). Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 466(7302 ): 113-117. Higgins, Claire A., Westgate, Gillian E. & Jahoda, Colin A. B. (2009). From telogen to exogen: mechanisms underlying formation and subsequent loss of the hair club fiber. Journal of Investigative Dermatology 129: 2100-2108. Richardson, GD, Bazzi, H, Fantauzzo, KA, Waters, JM, Crawford, H, Hynd, P, Christiano, AM & Jahoda, CA (2009). KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development 136(13): 2153-2164. Wojciechowicz, K, Markiewicz, E & Jahoda CA (2008). C/EBPalpha identifies differentiating preadipocytes around hair follicles in foetal and neonatal rat and mouse skin. Experimental Dermatology 17(8): 675-680. Reynolds A.J. & Jahoda C.A.B. (2004). Cultured human and rat tooth papilla cells induce hair follicle regeneration and fiber growth. Differentiation 72(9-10): 566-575. Jahoda, CAB, Kljuic, A, O'Shaughnessy, R, Crossley, N, Whitehouse, CJ, Robinson, M, Reynolds, AJ, Demarchez, M, Porter, RM, Shapiro, L & Christiano, AM (2004). The lanceolate hair rat phenotype results from a missense mutation in a calcium coordinating site of the desmoglein 4 gene. Genomics 83(5): 747-756. Fliniaux I., Viallet J.P. Dhouailly D. & Jahoda C.A.B. (2004). Transformation of amnion epithelium into skin. Differentiation 72: 558-565. Kljuic, A, Bazzi, H, Sundberg, JP, Martinez-Mir, A, O'Shaughnessy, R, Mahoney, MG, Levy, M, Montagutelli, X, Ahmad, W, Aita, VM, Gordon, D, Uitto, J, Whiting, D, Ott, J, Fischer, S, Gilliam, TC, Jahoda, CAB, Morris, RJ, Panteleyev, AA, Nguyen, VT & Christiano, AM (2003). Desmoglein 4 in hair follicle differentiation and epidermal adhesion: Evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell 113(2): 249-260. Jahoda, CAB, Whitehouse, CJ, Reynolds, AJ & Hole, N (2003). Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages. Experimental Dermatology 12(6): 849-859. Gharzi, A., Reynolds A.J. & Jahoda, C.A.B. (2003). Plasticity of hair follicle dermal cells in wound healing and induction. Exp. Dermatol (12): 126-136. Whitehouse, C.J., Huckle, J.W. & Reynolds, A.J.and Jahoda C.A.B. (2002). Genes that are differentially expressed in rat vibrissa follicle germinative epithelium in vivo show altered expression patterns after extended organ culture. Exp. Dermatol (11): 542-555. Lako, M., Armstrong, L., Cairns, P.M., Harris, S., Hole, N. & Jahoda C.A.B. (2002). Hair follicle dermal cells repopulate the mouse haematopoietic system. Journal of Cell Science 115(20): 3967-3974. Busby, W., Cameron, N.R. & Jahoda, C.A.B. (2002). Tissue engineering matrixes by emulsion templating. Polymer international 51(10): 871-881. Jahoda, CAB & Reynolds, AJ (2001). Hair follicle dermal sheath cells: unsung participants in wound healing. Lancet 358(9291): 1445-1448. Robinson, M., Reynolds, A.J. , Gharzi, A. & Jahoda, C.A.B. (2001). In vivo induction of hair growth by dermal cells isolated from hair follicles after extended organ culture. Journal of Investigative Dermatology 117(3): 596-604. Jahoda, C.A.B., Oliver, R.F., Reynolds, A.J., Forrester, J.C., Gillespie, J.W., Cserhalmi-Friedman, P.B., Christiano, A.M. & Horne, K.A. (2001). Trans-species hair growth induction by human hair follicle dermal papillae. Exp. Dermatol 10(4): 229-237. Ferraris, C., Chevalier, G., Favier, B., Jahoda, C.A.B. & Dhouailly, D. (2000). Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous, and sweat gland genetic programs in response to embryonic dermal stimuli. Development (127): 5487-5495. Reynolds, A.J., Lawrence, C., Cserhalmi-Friedman, P.B., Christiano, A.M. & Jahoda C.A.B. (1999). Trans-gender induction of hair follicles. Nature (402): 33-34. Reynolds, A.J. & Jahoda, C.A.B. (1996). Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells. Development (122): 3085-3094. Jahoda, C.A.B., Horne, K.A., Mauger, A., Bard, S. & Sengel, P. (1992). Cellular and extracellular involvement in the regeneration of the rat vibrissa follicle. Development (114): 887-897. Reynolds, A.J. & Jahoda, C.A.B. (1992). Cultured dermal papilla cells induce follicle formation and hair growth by transdifferentiation of an adult epidermis. Development (115): 587-593.