徐哲 - 香港中文大学

个人简介

Education 2013–2015 Postdoctoral Fellow Max-Planck-Institut für Kohlenforschung, Germany (with Prof. Benjamin List, Nobel laureate 2021) 2008-2013 Ph.D. University of Toronto, Canada (with Prof. Mark Lautens, Officer of the Order of Canada) 2011 Visiting Scholar Kyoto University, Japan (with Prof. Tamio Hayashi) 2004-2006 M.Sc. University of Guelph, Canada (with Prof. William Tam) 2000-2004 B.Sc. (Hons.) University of Guelph, Canada Position 2022-present Associate Professor, The Chinese University of Hong Kong, Hong Kong 2015-2022 Assistant Professor, The Chinese University of Hong Kong, Hong Kong

研究领域

Organofluorine chemistry Homogeneous catalysis Asymmetric synthesis Pharmaceutical, agrochemical and material applications

近期论文

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New Avenues in Copper-Mediated Trifluoromethylation Reactions Using Fluoroform as the CF3 Source. Yang, X.; Tsui, G. C.* Synlett 2022, 33, A–H. Construction of Carbon-Fluorine Bonds via Copper-Catalyzed/-Mediated Fluorination Reactions. Dong, T.; Tsui, G. C.* Chem. Rec. 2021, 21, 4015–403. Palladium-Catalyzed Stereoselective C−F Bond Vinylation and Allylation of Tetrasubstituted gem-Difluoroalkenes via Stille Coupling: Synthesis of Monofluorinated 1,3- and 1,4-Dienes. Li, M.; Wang, Y.; Tsui, G. C.* Org. Lett. 2021, 23, 8072-8076. Nucleophilic Vinylic Substitution (SNV) of Trisubstituted Monofluoroalkenes for the Synthesis of Stereodefined Trisubstituted Alkenes and Divinyl Ethers. Zong, Y.; Ma, Q.; Tsui, G. C.* Org. Lett. 2021, 23, 6169-6173. Stereoselective Synthesis of Difluorinated 1,3-Dienes via PalladiumCatalyzed C−F Bond Activation of Tetrasubstituted gem-Difluoroalkenes. Wang, Y.; Ma, Q.; Tsui, G. C.* Org. Lett. 2021, 23, 5241-5245. Stereoselective Palladium-Catalyzed Base-Free Suzuki–Miyaura Cross-Coupling of Tetrasubstituted gem-Difluoroalkenes: An Experimental and Computational Study. Wang, Y.; Qi, X.; Ma, Q.; Liu, P.;* Tsui, G. C.* ACS Catal. 2021, 11, 4799-4809. Perfluoroalkylation of Thiosulfonates: Synthesis of Perfluoroalkyl Sulfides. Luo, Z.; Yang, X.; Tsui, G. C.* Org. Lett. 2020, 22, 6155-6159. Palladium-Catalyzed Stereoselective Hydrodefluorination of Tetrasubstituted gem-Difluoroalkenes. Ma, Q.; Liu, C.; Tsui, G. C.* Org. Lett. 2020, 22, 5193-5197. Radical Pentafluoroethylation of Unactivated Alkenes Using CuCF2CF3. Yang, X.; Tsui, G. C.* Org. Lett. 2020, 22, 4562-4567. Stereoselective Palladium‐Catalyzed C−F Bond Alkynylation of Tetrasubstituted gem‐Difluoroalkenes. Ma, Q.; Wang, Y.; Tsui, G. C.* Angew. Chem. Int. Ed. 2020, 59, 11293-11297. Silver-Catalyzed Trifluoromethylalkynylation of Unactivated Alkenes with Hypervalent Iodine Reagents. Yang, X.; Tsui, G. C.* Org. Lett. 2019, 21, 8625-8629. Trifluoromethylation of Anthraquinones for n-Type Organic Semiconductors in Field Effect Transistors. Zhao, M.; Yang, X.; Tsui, G. C.*; Miao, Q.* J. Org. Chem. 2020, 85, 44-51. Trifluoromethylation of Unactivated Alkenes with Me3SiCF3 and N-Iodosuccinimide. Yang, X.; Tsui, G. C.* Org. Lett. 2019, 21, 1521-1525. Domino Cyclization/Trifluoromethylation of 2-Alknylphenols for the Synthesis of 3-(Trifluoromethyl)benzofurans and Evaluation of Their Antibacterial and Antifungal Activities. Li, M.; Ye, Y.; He, L.; Hui, M.; Ng, T. B.; Wong, J. H.; Tsui, G. C.* Asian J. Org. Chem. 2019, 8, 702-709. Trifluoromethylation of α-Diazoesters and α-Diazoketones with Fluoroform-Derived CuCF3: Synergistic Effects of Co-Solvent and Pyridine as a Promoter. Ma, Q.; Tsui, G. C.* Org. Chem. Front. 2019, 6, 27-31. Copper-Mediated 1,2-Bis(trifluoromethylation) of Arynes. Yang, X.; Tsui, G. C.* Chem. Sci. 2018, 9, 8871-8875. Domino Cyclization/Trifluoromethylation of 2-Alkynylanilines Using Fluoroform-Derived CuCF3: Synthesis of 3-(Trifluoromethyl)indoles. Ye, Y.; Cheung, K. P. S.; He, L.; Tsui, G. C.* Org. Chem. Front. 2018, 5, 1511-1515. Synthesis of 2-(Trifluoromethyl)indoles via Domino Trifluoromethylation/Cyclization of 2-Alkynylanilines. Ye, Y.; Cheung, K. P. S.; He, L.; Tsui, G. C.* Org. Lett. 2018, 20, 1676-1679. Copper-Mediated Domino Cyclization/Trifluoromethylation of Propargylic N‐Hydroxylamines: Synthesis of 4‐Trifluoromethyl-4- isoxazolines. Wang, Q.; Tsui, G. C.* J. Org. Chem. 2018, 83, 2971-2979. Copper-Mediated Trifluoromethylation-Allylation of Arynes. Yang, X.; Tsui, G. C.* Org. Lett. 2018, 20, 1179-1182.