Ambler, Carrie A. - Durham University - School of Biological and Biomedical Science

研究领域

Understanding how cell-cell interactions regulate skin stem cells

近期论文

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Li, Z., Hodgkinson, T., Gothard, E.J., Boroumand, S., Lamb, R., Cummins, I., Narang, P., Sawtell, A., Coles, J., Leonov, G., Reboldi, A., Buckley, C.D., Cupedo, T., Siebel, C., Bayat, A., Coles, M.C. & Ambler, C.A. (2016). Epidermal Notch1 recruits RORgamma+ group 3 innate lymphoid cells to orchestrate normal skin repair. Nature Communications 7: 11394. Wojciechowicz, K., Gledhill, K., Ambler, C.A., Manning, C.B. & Jahoda, C.A.B. (2013). Development of the mouse dermal adipose layer occurs independently of subcutaneous adipose tissue and is marked by restricted early expression of FABP4. PLoS ONE 8(3): e59811. Lamb, R. & Ambler, C.A. (2013). Keratinocytes propagated in serum-free, feeder-free culture conditions fail to form stratified epidermis in a reconstituted skin model. PLoS ONE 8(1): e52494. Ambler, C. A. & Watt, F. M. (2010). Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of Jagged 1. Development 137(21): 3569-3579. Ambler, C. A. & Maatta, A. (2009). Epidermal stem cells: location, potential and contribution to cancer. Journal of Pathology 217: 206–216. Watt, F. M., Estrach, S. & Ambler, C. A. (2008). Epidermal Notch signalling: differentiation, cancer and adhesion. Current Opinion in Cell Biology 20: 171-179. Ambler, C. A. & Watt, F. M. (2007). Expression of notch pathway genes in mammalian epidermis and modulation by beta-catenin. Developmental Dynamics 236(6): 1595-1601. Estrach, S., Ambler, C. A., Lo Celso, C., Hozumi, K. & Watt, F. M. (2006). Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development 133(22): 4427-4438. Bautch, V. L. & Ambler, C. A. (2004). Assembly and Patterning of vertebrate blood vessels. Trends In Cardiovascular Medicine 14(4): 138-143. Hogan, K. A., Ambler, C. A., Chapman, D. L. & Bautch, V. L. (2004). The neural tube patterns vessels developmentally using the VEGF signaling pathway. Development 131(7): 1503-1513. Ambler, C. A., Schmunk, G. M. & Bautch, V. L. (2003). Stem cell-derived endothelial cells/progenitors migrate and pattern in the embryo using the VEGF signaling pathway. Developmental Biology 257(1): 205-219. Kearney, J. B., Ambler, C. A., Monaco, K. A., Johnson, N., Rapoport, R. G. & Bautch, V. L. (2002). Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99(7): 2397-2407. Ambler, C. A., Nowicki, J. L., Burke, A. C. & Bautch, V. L. (2001). Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts. Developmental Biology 234(2): 352-364.