个人简介
主要从事软飞行器力学、多孔材料热-流-固耦合理论、细胞与细胞核力学、植物力学等研究工作。主持国家自然科学基金、江苏省自然科学基金等项目5项,作为骨干参与国家自然科学基金重点项目1项。已在Appl. Mech. Rev., JMPS(5篇), Soft Matter, Nonlinear Dynamics, Phys. Fluids,ACS Appl. Mater. & Inter., ACS Biomater. Sci. Eng., Plant, Cell & Environment, J. Mech. Behav. Biomed., Biophys. J., Acta Mech Sinica, 物理学报、力学学报等国内外学术期刊上发表论文40余篇、专著章节2章。其中6篇被选为封面论文。是New Phytologist、Nonlinear Dynamics、Biophys. J.等领域内顶级期刊审稿人,《应用数学和力学》期刊编委。获2018全国生物力学大会青年学者优秀论文奖,入选2019年江苏省“双创博士”人才项目。依托“机械结构力学及控制国家重点实验室”和“多功能轻量化材料与结构工信部重点实验室”研究平台,所在课题组“多功能轻量化材料与结构研究中心”是南京航空航天大学大力支持建设的力学及交叉学科研究中心,课题组负责人卢天健教授为我国超轻多孔材料和结构、生物组织热-力-电耦合学领域的主要学术带头人。现有“杰出青年基金”获得者1人、江苏省“双创计划”3人、教授/副教授6人、讲师3人、博士后3人,已形成了具有高水平科研能力的人员梯队,团队成员具有良好的研究与合作基础。课题组立足于多学科交叉的理念,长期致力于力学、材料学、传热学、声学、生命科学等多个学科的综合交叉基础和应用研究,并设有“材料制备与加工”,“冲击动力学”、“微结构刻画与力学表征”、“振动与噪声控制”、“热流体”、“仿生力学”及“高性能计算”等实验室。
工作经历
• 2019年5月-今,南京航空航天大学,航空学院力学系,副研究员
• 2018年11月-2019年5月,南京航空航天大学,航空学院力学系,讲师
• 2018年05月-2018年11月,西安交通大学,仿生工程与生物力学中心,助理研究员,合作导师 徐峰教授
教育经历
• 2015年3月-2016年12月,美国华盛顿大学(圣路易斯),机械工程与材料科学,联合培养博士生,导师 Guy M. Genin教授
• 2012年9月-2018年3月,西安交通大学,力学,硕博连续,导师 卢天健教授
• 2007年9月-2011年7月,西安理工大学,工程力学,学士,导师 吴莹教授、曹小杉教授
教学情况
本科生课程《从交叉学科角度认识新一代超轻多孔材料》,含液多孔材料力学部分,4学时,春季、秋季
研究生课程《生物力学基础》,32学时,春季
研究生课程《软材料微尺度力学性能测试》,16学时,秋季
参与组织学术会议
1. International Symposium on the Mechanics of Liquid-Filled Porous Materials, Oct. 31-Nov. 2, 2019, Xi’an, China
2. 专题研讨会MS05 轻质多孔材料及结构的基础理论及应用, 中国力学大会-2019, 2019年8月25-28日,浙江杭州
3. IUTAM Symposium on Mechanical Environments of Living Cells, June 28-30, 2018, Xi’an, China
4. 中国力学大会-2013, 2013年8月19-21日,陕西西安
5. The 18th International Conference on Mechanics in Medicine and Biology (ICMMB-18), October 16-19, 2012 Xi’an, China
6. Joint US/Chinese Cellular Biomechanics Summer Institute for Young Investigators, August 15-17, 2012, Xi'an, China
7. The Second International Workshop on Bioengineering and Biomechanics (Bio-2011), Xi’an, China, August 12-14, 2011
参加学术会议
1. 刘少宝. 生物含液多孔材料跨尺度流固-耦合问题研究. 第四届全国生物力学青年学者学术研讨会. 2020年11月21-22 日,浙江杭州
2. 刘少宝. 核孔复合体核篮构型模态转换的力-电调控. 中国力学大会-2019, 2019年8月25-28日,浙江杭州
3. 刘少宝. 充液毛细管振动的理论与实验研究. 中国力学大会-2019, 2019年8月25-28日,浙江杭州
4. 刘少宝. 微管的流-固耦合力学:声学、振动与波动. 2019先进多功能材料与结构动力学学术研讨会,2019年07月25-28,黑龙江牡丹江
5. Shaobao Liu. Mechano-electrical transduction and dynamical response of Arabidopsis trichome. First Sino-Italian Workshop on Biomechanics, July 1-3, 2019, Rome, Italy
6. 刘少宝,刘含,卢天健,徐峰. 植物表皮毛细胞(trichome)的力-电转导及动力学响应特性研究. 2018全国固体力学学术会议, 2018年11月23-25日,黑龙江哈尔滨
7. 刘少宝. 细胞的振动与声学特性. 2018先进多功能材料与结构动力学学术研讨会,2018年11月03-05日,江苏苏州
8. 刘少宝,杨海谦,徐峰,卢天健. 核孔复合体连续力学模型. 第12届全国生物力学大会,2018年8月17-21日,陕西西安
9. Shaobao Liu, Ru Tao, Tianjian Lu, et al. Continuum model of the nuclear pore complex. EMBO Workshop on Nuclear mechano-genomics. April 17-20, 2018, Singapore.
10. Shaobao Liu, Weizbauer, R, Zhou, LH, Xu, F, Ehrhardt, D, Pickard, BG, Genin, GM. Models of perimembrane mechanics in plant cell mechanobiology. Third International Symposium on Mechanobiology. December 11-14, 2017, Singapore.
11. Shaobao Liu, Barbara G. Pickard, Guy M. Genin. Mechanoresponse of Arabidopsis trichomes to sounds such as emitted by feeding caterpillars. 2016 Plant Cell Dynamics Meeting, June 21 - 24, 2016, St. Louis, USA
12. ShaoBao Liu, PengFei Wang, GuoYou Huang, Lin Wang, JinXiong Zhou, Tian Jian Lu, Feng Xu. Kinetic modelling of chemomechanical behavior of ionic gels. 7th World Congress of Biomechanics, July 6–11, 2014, Boston, USA
13. Shaobao Liu, Lihong Zhou, Renate A.Weizbauer, Min Lin, Barbara G. Pickard, David A. Ehrhardt, TJ Lu, Guy M. Genin, Feng Xu. Induction of drought resistance at the plant cell periphery: a role for arabinogalactan proteins. 2013 Annual Meeting of the Chinese Society for Applied Mechanics, Xi’an, China.
14. Shaobao Liu, Lihong Zhou, Renate A.Weizbauer, Min Lin, Barbara G. Pickard, David A. Ehrhardt, TianJian Lu, Guy M. Genin, Feng Xu. The role of interfacial mechanical phenomena at the plant cell periphery in the preparation of plant cells for drought. 13th International Conference on Fracture (ICF13), June 16 –21 , 2013, Beijing, China
15. 刘少宝,周丽宏,林敏,卢天健,徐峰. 干旱诱导的植物细胞壁-膜界面蛋白相转换. 第一届全国植物逆境生物学学术研讨,2013年5月9-13日,陕西杨凌
16. 刘少宝,王鹏飞,徐峰,卢天健. 聚电解质凝胶的力-电-化耦合模型研究. 中国力学大会-2013, 2013年8月19-21日,陕西西安
教育经历
2015.3 - 2016.12 美国圣路易斯华盛顿大学 机械工程与材料科学 其他 无学位
工作经历
2019.1 - 至今 南京航空航天大学 航空学院 副研究员 在职
2018.11 - 2018.12 南京航空航天大学 航空学院 讲师 在职
科研项目
[1] 刘少宝双创博士项目
[2] 2019双创博士刘少宝
[3] 皮肤/肌肉细胞及细胞核力学性能测试
[4] 扫描电子显微镜及膜片钳测试
[5] 植物表皮毛细胞响应声波刺激的力-电转导及动力学机制
[6] 植物表皮毛细胞响应声波刺激的力-电转导及动力学机制
[7] 腱-骨界面的力学梯度特征:形成机制、体外构建及诱导干细胞分化
近期论文
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1. J. Yin, H. Liu, J. Jiao, X. Peng, B.G. Pickard5, G.M. Genin5, T.J. Lu#, S.B. Liu# Ensembles of the leaf trichomes of Arabidopsis thaliana selectively vibrate in the frequency range of its primary insect herbivore. Extreme Mechanics Letters, 2021, 48, 101377
2. S.B. Liu*, H.Q. Yang*, M. Wang, J. Tian, Y. Hong, Y. Li, G. M. Genin, T. J. Lu#, Feng Xu# Torsional and Translational Vibrations of a Eukaryotic Nucleus, and the Prospect of Vibrational Mechanotransduction and Therapy. Journal of the Mechanics and Physics of Solids, 2021, 155, 104572
3. H. Liu, S.B. Liu, G. Huang, F. Xu Effect of Gene Mutation of Plant on Their Mechano-Sensibility: Mutant of EXO70H4 Influences the Buckling of Arabidopsis Trichomes. Analyst, 2021
4. L. Chang, Y. Li, M. Li, S.B. Liu, et al. An Injectable, biodegradable magnetic hydrogel system for exogenous promotion of muscle mass and regeneration. Chemical Engineering Journal, 2021, 420
5. X. Chen, F. Ti, M. Li, S.B. Liu, T.J. Lu Theory of fluid saturated porous media with surface effects. Journal of the Mechanics and Physics of Solids, 2021, 151, 104392
6. X. Sun, X. Chen, M. Wang, M. Li Y. Liu, S.B. Liu*, Tian Jian Lu* Characterizing in situ poroelastic properties of cytoplasm by the translation of a rigid spherical inclusion. Acta Mechanica Sinica, 2020. (DOI : 10.1007/s10409-020-01038-y)
7. F. Ti, X. Chen, H. Yang, S.B. Liu*, T. J. Lu* A theory of mechanobiological sensation: strain amplification/attenuation of coated liquid inclusion with surface tension. Acta Mechanica Sinica, 2020. (DOI :10.1007/s10409-020-01017-3)
8. S.B. Liu, H. Liu, J.J. Jiao, J. Yin, T.J. Lu, F. Xu Biomechanics in plant resistance to drought. Acta Mechanica Sinica, 2020, 36: 5. (Journal Cover)
9. S.B. Liu#, Y. Wu#, F. Yang, M. Li, X. Kou, C. Lei, F. Xu, T.J. Lu Vibration of a liquid-filled capillary tube, Journal of the Mechanical Behavior of Biomedical Materials, 2020, 42: 103745.
10. Y. Wu, M. Li, J. Yin, S.B. Liu*, T.J. Lu* Hydrostatic pressure and interfacial tension induce mode instability in wave propagation along a liquid-filled microtubule, Physics of Fluids, 2020, 32: 031901.
11. M. Wang#, S.B. Liu#, Z. Xu, K. Qu, M. Li, X. Chen, Q. Xue, G.M. Genin, F. Xu, T.J. Lu Characterizing poroelasticity of biological tissues by spherical indentation: An improved theory for large relaxation. Journal of the Mechanics and Physics of Solids, 2020, 138, 103920.
12. S.B. Liu, H. Yang, T. J. Lu, G. M. Genin, F. Xu Electrostatic switching of nuclear basket conformations provides a potential mechanism for nuclear mechanotransduction, Journal of the Mechanics and Physics of Solids, 2019, 133: 103705
13. H. Liu, M. Li, S.B. Liu, P. Jia, X. Guo, S. Feng, T. J. Lu, H. Yang, F. Li, F. Xu Spatially modulated stiffness on hydrogels for soft and stretchable integrated electronics, Materials Horizons, 2019, DOI: 10.1039/c9mh01211g
14. S.B. Liu, R. Tao, M. Wang, J. Tian, G.M. Genin, T.J. Lu, F. Xu, Regulation of cell behavior by hydrostatic pressure, Applied Mechanics Reviews, 2019, 71: 040803.
15. M Wang, S.B. Liu, F Li. Imaging oxygen microenvironment in hydrogel microwell array. Acta Mechanica Sinica, 2019, 35(2):321–328.
16. S.B. Liu, H. Yang, Z.T. Bian, R. Tao, X. Chen, T.J. Lu. Regulation on mechanical properties of spherically cellular fruits under osmotic stress, Journal of the Mechanics and Physics of Solids, 2019, 127, 182-190
17. X. Chen, M. Li, S.B. Liu, F. Liu, G.M. Genin, F. Xu, T.J. Lu, Translation of a coated rigid spherical inclusion in an elastic matrix: exact solution, and implications for mechanobiology, Journal of Applied Mechanics, 2019, 86, 1–28
18. D. Pei, X. Hu, C. Jin, Y. Lu, S.B. Liu*, Energy storage and dissipation of human periodontal ligament during mastication movement. ACS Biomaterials Science & Engineering, 2018, 4, 4028−4035.
19. X. Chen M. Li, M. Yang, S.B. Liu, G. M. Genin, F. Xu, T.J. Tian. The elastic fields of a compressible liquid inclusion. Extreme Mechanics Letters, 2018, 22, 122–130.
20. Y. Li, Y. Hong, G. K. Xu, S.B. Liu, Q. Shi, D. Tang. Non-contact tensile viscoelastic characterization of microscale biological materials. Acta Mechanica Sinica, 2018, 34(3):589–599.
21. C. Ji, F. Song, G. Huang, S. Wang, H. Liu, S.B. Liu, L. Huang, S. Liu, J. Zhao, T. J. Lu, F. Xu. The protective effects of acupoint gel embedding on rats with myocardial ischemia-reperfusion injury. Life Sciences, 2018, 211(15): 51-62.
22. S. B. Liu, J. J. Jiao, T. J. Lu, F. Xu, B. G. Pickard, G. M. Genin. Arabidopsis leaf trichomes as acoustic antennae. Biophysical Journal, 2017, 113(9): 2068. (Journal Cover)
23. S.B. Liu, Liu H, S.S. Feng, M. Lin, F. Xu, T.J. Lu. Fountain streaming contributes to fast tip-growth through regulating the gradients of turgor pressure and concentration in pollen tubes. Soft Matter, 2017. (Back Cover)
24. S.B. Liu, P.F. Wang, G.Y. Huang, L. Wang, J. X. Zhou, T. J. Lu, F. Xu, M. Lin. Reaction-induced swelling of ionic gels. Soft matter 2015, 11(3): 449-455. (Inside Cover)
25. S.B. Liu, Y. Wu, J.J. Li, Y. Xie, N. Tan. The dynamical behavior of spiral wave in stochastic Hodgkin-Huxley neuronal networks with ion channel block. Nonlinear Dynamics, 2013, 73(1-2): 1055-1063
26. S.B. Liu, H. Liu, M. Lin, F. Xu, T.J. Lu. Intracellular microfluid transportation in fast growing pollen tubes. Modeling of Microscale Transport in Biological Processes, Chapter 6, Elsevier 2016
27. S.B. Liu, Y. Wu, Z.W. Hao, Y.J. Li, N. Jia. Effects of sodium and potassium ion channel fluctuation on the spatiotemporal patterns of neuronal network. Acta Physica Sinica 物理学报 2012 61(2) 020503 (SCI, in Chinese)
28. S.B. Liu, Y. Wu, Z.W. Hao, Y.J. Li, N. Jia. The effect of local defect without diffusion function on spatiotemporal patterns of random neural network. Journal of Dynamics and Control 动力学与控制 201210(1) 81 (in Chinese)
29. S.B. Liu, Y. Wu. Effect of Channel Gauss Noise of the Neuronal Network Dynamic Behaviors. Journal of Dynamics and Control 动力学与控制 2010 08(3)284 (in Chinese)
30. M. Lin, S. B. Liu, G. M. Genin, Y. J. Zhu, M. Shi, C. C. Ji, T. J. Lu, F. Xu. Melting away pain: decay of thermal nociceptor transduction during heat-induced irreversible desensitization of ion channels. ACS Biomaterials Science & Engineering, 2017.
31. H. Liu, S.B. Liu, J. J. J., T. J. Lu, F. Xu. Trichome as the natural biophysical barrier for plants and its bioinspired applications. Soft Matter, 2017, 13(30): 5096-5106. (Journal Cover)
32. J. Li, S.B. Liu, W. Liu, Y. Yu, Y. Wu. Suppression of firing activities in neuron and neurons of network induced by electromagnetic radiation. Nonlinear Dynamics, 2016, 83(1-2): 801-810.
33. L.H. Zhou, S.B. Liu, P.F. Wang, T.J. Lu, F. Xu, G.M. Genin, B. G. Pickard. The Arabidopsis trichome is an active mechanosensory switch. Plant, cell & environment (2016). (Journal Cover)
34. M. Lin, S.B. Liu, L. Niu, F. Xu, T.J. Lu. Analysis of thermal-induced dentinal fluid flow and its implications in dental thermal pain. Archives of Oral Biology, 2011, 56(9): 846–854
35. P.F. Wang, S.B. Liu, J.X. Zhou, F. Xu, T.J. Lu. Kinetic modelling and bifurcation analysis of chemomechanically miniaturized gels under mechanical load. European Physical Journal E, 2013, 36(108): 13108-13117
36. M. Lin, S.B. Liu, F. Xu, T.J. Lu, G.M. Genin. Thermal pain in tooth: heat transfer, thermomechanics, and ion transport.Chapter 2, Transport in Biological Media, Elsevier 2013
37. T. Li, S.B. Liu, M.M. Li, Y. Wu, Y.M. Li. Influences of the cochlear structure on the dispersion of low-frequency signals. Applied Mathematics and Mechanics 应用数学与力学 2014, 35(8) (SCI, in Chinese)
38. P.F. Wang, S.B. Liu, J.X. Zhou, T.J. Lu, F. Xu. Dynamic model of self-oscillating gels and the controllability analysis. Chinese Journal of Theoretical and Applied Mechanics 力学学报 2013 456 (EI, in Chinese)
39. M. Lin, S.B. Liu, L. Niu, F. Xu, T.J. Lu. Modeling and perfecting of hydrodynamic hypothesis for tooth thermal pain. Journal of Xi'an Jiaotong University 西安交通大学学报 2011 45(12) 117 (EI, in Chinese)
40. F. Liu, C. Li, S.B. Liu, G. M. Genin, G Huang, T.J. Lu, F. Xu. Effect of viscoelasticity on skin pain sensation. Theoretical and Applied Mechanics Letters, 2015, 5(6): 222-226.
41. Y.L. Han, Y.S. Yang, S.B. Liu, J.H. Wu, Y.M. Chen, T.J. Lu, F. Xu. Directed self-assembly of microscale hydrogels by electrostatic interaction. Biofabrication, 2013, 5(3): 035004-035014
42. Y. Wu, J.J. Li, S.B.Liu, J.Z.Pang, M.M. Du, P. Lin. Noise-induced spatiotemporal patterns in Hodgkin–Huxley neuronal network. Cogn Neurodyn 2013 7(5): 431 (SCI, IF=1.742)
43. R.Wang, Y.Wu, S.B. Liu. Effect of ion channel random blocking on the spatiotemporal dynamics of neuronal network. Acta Physica Sinica 物理学报 2013 62(22): 220504 (SCI, in Chinese)
44. M. Lin, F.S. Liu, S.B. Liu, Changchun Ji, Ang Li, Tian Jian Lu, Feng Xu. The race to the nociceptor: mechanical versus temperature effects in thermal pain of dental neurons. Acta Mechanica Sinica (2017) 33(2):260–266
45. L. Wang, Y. Li, B. Chen, S.B. Liu, M. Li, L. Zheng, P. Wang, T.J. Lu,. F. Xu, Patterning cellular alignment through stretching hydrogels with programmable strain gradients. ACS Applied Materials & Interfaces, 2015, 7(27): 15088-15097.
46. H. Liu, L.H. Zhou, J. Jiao, S.B. Liu, Z. Zhang, T.J. Lu, F. Xu, (2016). Gradient mechanical properties facilitate arabidopsis trichome as mechanosensor. ACS Applied Materials & Interfaces, 2016, 8(15): 9755-9761.
[1] 刘少宝,,等.Regulation of cell behavior by hydrostatic pressure.Applied Mechanics Reviews,2019
[2] 刘少宝,,等.Electrostatic switching of nuclear basket conformations provides a potential mechanism for nuclear mechanotransduction.Journal of the Mechanics and Physics of Solids,2019
[3] 刘少宝,刘少宝,刘少宝.Regulation of cell behavior by hydrostatic pressure
[4] 刘少宝,刘少宝,刘少宝等.Electrostatic switching of nuclear basket conformations provides a potential mechanism for nuclear mechanotransduction