研究领域

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Biomolecular investigations of the aetiology and pathogenesis of inflammatory and cardiovascular diseases; The role of ‘oxidative stress’ in the pathogenesis of human diseases; The multicomponent high-resolution NMR analysis of biofluids and tissues for diagnostic, prognostic and forensic purposes; Biomedical, bioanalytical and metabolomic investigations of oral diseases and the therapeutic activities of oral healthcare products; The development and application of techniques for the monitoring of drugs of both clinical and forensic interest; Synthesis, applications and mechanisms of action of drugs and metallodrugs; Pharmacology and pharmacodynamics (both clinical and forensic aspects); The biological and medicinal chemistry of reactive oxygen species (ROS), together with the detection and pathological significance of products derived from their reactions, both in vitro and in vivo; Biological inorganic chemistry, for example the ‘speciation’ of metal ions in biofluids and tissues; The development and testing of novel biomaterials and biosensors; Bio- and chemometrics, and metabolomics, including NMR-based exploratory data analysis and pattern recognition techniques; Design, development and testing of metal alloy oral and joint prostheses; The experimental design of clinical trials and statistical analysis of data derived therefrom; Research ethics of clinical investigations