黄怀义 - 中山大学

个人简介

2007年-2011年本科，中山大学，材料化学 2011年-2016年博士，中山大学，化学生物学 2015年-2016年博士联合培养，University of Zurich, Switzerland 2016年-2018年博士后，牛顿学者, University of Warwick，UK 2018年-至今：中山大学药学院（深圳），“百人计划”副教授，博士生导师

研究领域

本课题组致力于新型金属配合物的构建及其化学生物学应用研究，研究方向聚焦于金属配合物在肿瘤诊疗领域的应用，课题组围绕肿瘤光动力/光催化治疗金属光敏剂、耐药性肿瘤化疗金属药物、肿瘤微环境检测磷光金属配合物三个研究方向开展了系列创新性研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Z. Zhang; Huaiyi Huang; Breakthrough in construction of oxygen-independent photose nsitizer for type III photodynamic therapy, SCIENCE CHINA Chem., 2022, DOI 10.1007/s11426-022 -1218-0. Z. Fan, Y. Rong, T. Sadhukhan, S. Liang, W. Li, Z. Yuan, Z. Zhu, S. Guo, S. Ji, J. Wang, R. Kushwaha, S. Banerjee,* K. Raghavachari, H. Huang*, Single-Cell Quantification of a Highly Biocompatible Dinuclear Iridium(III) Complex for Photocatalytic Cancer Therapy. Angewandte Chemie International Edition, 2022, DOI 10.1002/anie.202202098. C. Huang1, C. Liang1, T. Sadhukhan, S. Banerjee, Z. Fan, T. Li, Z. Zhu, P. Zhang, K. Raghavachari, H. Huang*, In-vitro and in-vivo photo-catalytic cancer therapy with biocompatible iridium(III) photo-catalysts. Angewandte Chemie International Edition, 2021, 60, 9474-9479. (Hot paper) C. Huang, T. Li, J. Liang, H. Huang*, P. Zhang*, S. Banerjee*, Recent advances in endoplasmic reticulum targeting metal complexes, Coordination Chemistry Reviews, 2020, 408, 213178. H. Huang1, S. Banerjee1, K. Qiu, P. Zhang, O. Blacque, T. Malcomson, M. Paterson, G. Clarkson, M. Staniforth, V. Stavros, G. Gasser*, H. Chao*, P. Sadler*, Targeted photoredox catalysis in cancer cells. Nature Chemistry, 2019, 11, 1041-1048. (高被引论文) C. Imberti1, P. Zhang1,*, H. Huang*, P. J. Sadler*, New designs for phototherapeutic transition metal complexes. Angewandte Chemie International Edition, 2020, 59, 61-73. (高被引论文) P. Zhang, H. Huang*, S. Banerjee, G. Clarkson, C. Ge, C. Imberti, P. J. Sadler*, Nucleus targeted organoiridium–albumin conjugate for photodynamic cancer therapy. Angewandte Chemie International Edition, 2019, 58, 2350-2354. (VIP paper) P. Zhang, C. K. C. Chiu, H. Huang, Y. P. Y. Lam, A. Habtemariam, T. Malcomson, M. J. Paterson, G. J. Clarkson, P. B. O’Connor*, H. Chao*, P. J. Sadler*, Organoiridium Photosensitizers Induce Specific Oxidative Attack on Proteins within Cancer Cells. Angewandte Chemie International Edition, 2017, 56, 14898 –14902. (VIP paper) H. Huang1, B. Yu1, P. Zhang, J. Huang, Y. Chen, G. Gasser*, L. Ji, H. Chao*, Highly charged ruthenium (ii) polypyridyl complexes as lysosome‐localized photosensitizers for two‐photon photodynamic therapy. Angewandte Chemie International Edition, 2015, 54, 14255-14258. (VIP paper, 高被引论文) H. Huang1, L. Yang1, P. Zhanga, K. Qiu, J. Huang, Y. Chen, J. Diao, J. Liu, L. Ji, J. Long*, H. Chao*, Real-time tracking mitochondrial dynamic remodeling with two-photon phosphorescent iridium (III) complexes. Biomaterials 2016, 83, 321-331. H. Huang, P. Zhang, B. Yu, Y. Chen, L. Ji, H. Chao*, Targeting nucleus DNA with a cyclometalated dipyridophenazine ruthenium(II) complex. Journal of Medicinal Chemistry 2014, 57, 8971-8983. (JMC Highly Cited Paper)