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1. Zou, D., J. Pei, J. Lan, H. Sang, H. Chen, H. Yuan, D. Wu, Y. Zhang, Y. Wang, D. Wang, Y. Zou, D. Chen, J. Ren, X. Gao, and Z. Lin, A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption. EBioMedicine, 2020. 52: p. 102652.
2. Zheng, J., D. Wang, Q. Chen, Q. Liu, Z. Lin, Q. Hu, X. Wu, X. Gao, Q. Li, and J. Ren, Hypertonic saccharide solution delays pyroptosis in murine macrophages regardless of the membrane binding of gasdermin D N-terminal. Eur J Immunol, 2020. 50(3): p. 464-467.
3. Zhang, T., P. Xie, Y. Dong, Z. Liu, F. Zhou, D. Pan, Z. Huang, Q. Zhai, Y. Gu, Q. Wu, N. Tanaka, Y. Obata, A. Bradley, C.J. Lelliott, L.M.J. Nutter, C. McKerlie, A.M. Flenniken, M.F. Champy, T. Sorg, Y. Herault, M.H. Angelis, V.G. Durner, A.M. Mallon, S.D.M. Brown, T. Meehan, H.E. Parkinson, D. Smedley, K.C.K. Lloyd, J. Yan, X. Gao, J.K. Seong, C.L. Wang, R. Sedlacek, Y. Liu, J. Rozman, L. Yang, and Y. Xu, High-throughput discovery of genetic determinants of circadian misalignment. PLoS Genet, 2020. 16(1): p. e1008577.
4. Wang, D., J. Zheng, Q. Hu, C. Zhao, Q. Chen, P. Shi, Q. Chen, Y. Zou, D. Zou, Q. Liu, J. Pei, X. Wu, X. Gao, J. Ren, and Z. Lin, Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis. Cell Death Differ, 2020. 27(2): p. 466-481.
5. Lloyd, K.C.K., D.J. Adams, G. Baynam, A.L. Beaudet, F. Bosch, K.M. Boycott, R.E. Braun, M. Caulfield, R. Cohn, M.E. Dickinson, M.S. Dobbie, A.M. Flenniken, P. Flicek, S. Galande, X. Gao, A. Grobler, J.D. Heaney, Y. Herault, M.H. de Angelis, J.R. Lupski, S. Lyonnet, A.M. Mallon, F. Mammano, C.A. MacRae, R. McInnes, C. McKerlie, T.F. Meehan, S.A. Murray, L.M.J. Nutter, Y. Obata, H. Parkinson, M.S. Pepper, R. Sedlacek, J.K. Seong, T. Shiroishi, D. Smedley, G. Tocchini-Valentini, D. Valle, C.L. Wang, S. Wells, J. White, W. Wurst, Y. Xu, and S.D.M. Brown, The Deep Genome Project. Genome Biol, 2020. 21(1): p. 18.
6. Jiang, H., L. Zhang, X. Liu, W. Sun, K. Kato, C. Chen, X. Li, T. Li, Z. Sun, W. Han, F. Zhang, Q. Xiao, Z. Yang, J. Hu, Z. Qin, R.H. Adams, X. Gao, and Y. He, Angiocrine FSTL1 (Follistatin-Like Protein 1) Insufficiency Leads to Atrial and Venous Wall Fibrosis via SMAD3 Activation. Arterioscler Thromb Vasc Biol, 2020. 40(4): p. 958-972.
7. Huang, C., T. Liu, Q. Wang, W. Hou, C. Zhou, Z. Song, Y.S. Shi, X. Gao, G. Chen, Z. Yin, and Y. Hu, Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Developmentdagger. Cereb Cortex, 2020.
8. Zhou, S., Y. Li, L. Qiao, Y. Ge, X. Huang, X. Gao, H. Ju, W. Wang, J. Zhang, J. Yan, H. Teng, and Q. Jiang, Inactivation of Lkb1 in postnatal chondrocytes leads to epiphyseal growth-plate abnormalities and promotes enchondroma-like formation. FASEB J, 2019. 33(8): p. 9476-9488.
9. Zheng, M., D. Li, Z. Zhao, D. Shytikov, Q. Xu, X. Jin, J. Liang, J. Lou, S. Wu, L. Wang, H. Hu, Y. Zhou, X. Gao, and L. Lu, Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection. Proc Natl Acad Sci U S A, 2019. 116(25): p. 12422-12427.
10. Yuan, X., X. Qin, D. Wang, Z. Zhang, X. Tang, X. Gao, W. Chen, and L. Sun, Mesenchymal stem cell therapy induces FLT3L and CD1c(+) dendritic cells in systemic lupus erythematosus patients. Nat Commun, 2019. 10(1): p. 2498.
11. Xu, Q., X. Jin, M. Zheng, D. Rohila, G. Fu, Z. Wen, J. Lou, S. Wu, R. Sloan, L. Wang, H. Hu, X. Gao, and L. Lu, Phosphatase PP2A is essential for TH17 differentiation. Proc Natl Acad Sci U S A, 2019. 116(3): p. 982-987.
12. Wang, Y., P. Shi, Q. Chen, Z. Huang, D. Zou, J. Zhang, X. Gao, and Z. Lin, Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation. J Mol Cell Biol, 2019.
13. Wang, J., R. Xie, X. Kou, Y. Liu, C. Qi, R. Liu, W. You, J. Gao, and X. Gao, A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction. Mol Brain, 2019. 12(1): p. 51.
14. Quan, C., M. Li, Q. Du, Q. Chen, H. Wang, D. Campbell, L. Fang, B. Xue, C. MacKintosh, X. Gao, K. Ouyang, H.Y. Wang, and S. Chen, SPEG Controls Calcium Reuptake Into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain. Circ Res, 2019. 124(5): p. 712-726.
15. Ma, P., N.N. Song, Y. Li, Q. Zhang, L. Zhang, L. Zhang, Q. Kong, L. Ma, X. Yang, B. Ren, C. Li, X. Zhao, Y. Li, Y. Xu, X. Gao, Y.Q. Ding, and B. Mao, Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning. Cell Rep, 2019. 28(2): p. 541-553 e4.
16. Lai, S.S., X. Fu, Q. Cheng, Z.H. Yu, E.Z. Jiang, D.D. Zhao, D.C. Yu, Y.D. Qiu, X. Gao, H.X. Ju, W. Wang, Q. Jiang, M.S. Zhu, C.J. Li, and B. Xue, HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway. Am J Transl Res, 2019. 11(4): p. 2382-2392.
17. Giannuzzi, G., P.J. Schmidt, E. Porcu, G. Willemin, K.M. Munson, X. Nuttle, R. Earl, J. Chrast, K. Hoekzema, D. Risso, K. Mannik, P. De Nittis, E.D. Baratz, Y. Herault, X. Gao, C.C. Philpott, R.A. Bernier, Z. Kutalik, M.D. Fleming, E.E. Eichler, and A. Reymond, The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and Anemia Predisposition in Chromosome 16p11.2 Autism Individuals. Am J Hum Genet, 2019. 105(5): p. 947-958.
18. Geng, L., X. Tang, K. Zhou, D. Wang, S. Wang, G. Yao, W. Chen, X. Gao, W. Chen, S. Shi, N. Shen, X. Feng, and L. Sun, MicroRNA-663 induces immune dysregulation by inhibiting TGF-beta1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Cell Mol Immunol, 2019. 16(3): p. 260-274.
19. Gao, J., A. Qin, D. Liu, R. Ruan, Q. Wang, J. Yuan, T.S. Cheng, A. Filipovska, J.M. Papadimitriou, K. Dai, Q. Jiang, X. Gao, J.Q. Feng, H. Takayanagi, C. Zhang, and M.H. Zheng, Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network. Sci Adv, 2019. 5(11): p. eaaw7215.
20. Dai, J., S. Zhou, Q. Ge, J. Qin, J. Li, H. Ju, Y. Cao, M. Zheng, C. Li, X. Gao, H. Teng, and Q. Jiang, Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression. J Orthop Surg Res, 2019. 14(1): p. 59.
21. Chen, Q., P. Shi, Y. Wang, D. Zou, X. Wu, D. Wang, Q. Hu, Y. Zou, Z. Huang, J. Ren, Z. Lin, and X. Gao, GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity. J Mol Cell Biol, 2019. 11(6): p. 496-508.
22. Chen, Q., P. Shi, D. Wang, Q. Liu, X. Li, Y. Wang, D. Zou, Z. Huang, X. Gao, and Z. Lin, Epidermis-Activated Gasdermin-A3 Enhances Thermogenesis of Brown Adipose Tissue through IL-6/Stat3 Signaling. Am J Pathol, 2019. 189(5): p. 1041-1052.
23. Zou, J., B. Lai, M. Zheng, Q. Chen, S. Jiang, A. Song, Z. Huang, P. Shi, X. Tu, D. Wang, L. Lu, Z. Lin, and X. Gao, CD4+ T cells memorize obesity and promote weight regain. Cell Mol Immunol, 2018. 15(6): p. 630-639.
24. Yu, F., X. Han, K. Zhang, B. Dai, S. Shen, X. Gao, H. Teng, X. Wang, L. Li, H. Ju, W. Wang, J. Zhang, and Q. Jiang, Evaluation of a polyvinyl alcohol-alginate based hydrogel for precise 3D bioprinting. J Biomed Mater Res A, 2018.
25. Wang, Q., J. Tang, S. Jiang, Z. Huang, A. Song, S. Hou, X. Gao, and H.B. Ruan, Inhibition of PPARgamma, adipogenesis and insulin sensitivity by MAGED1. J Endocrinol, 2018.
26. Rozman, J., B. Rathkolb, M.A. Oestereicher, C. Schutt, A.C. Ravindranath, S. Leuchtenberger, S. Sharma, M. Kistler, M. Willershauser, R. Brommage, T.F. Meehan, J. Mason, H. Haselimashhadi, I. Consortium, T. Hough, A.M. Mallon, S. Wells, L. Santos, C.J. Lelliott, J.K. White, T. Sorg, M.F. Champy, L.R. Bower, C.L. Reynolds, A.M. Flenniken, S.A. Murray, L.M.J. Nutter, K.L. Svenson, D. West, G.P. Tocchini-Valentini, A.L. Beaudet, F. Bosch, R.B. Braun, M.S. Dobbie, X. Gao, Y. Herault, A. Moshiri, B.A. Moore, K.C. Kent Lloyd, C. McKerlie, H. Masuya, N. Tanaka, P. Flicek, H.E. Parkinson, R. Sedlacek, J.K. Seong, C.L. Wang, M. Moore, S.D. Brown, M.H. Tschop, W. Wurst, M. Klingenspor, E. Wolf, J. Beckers, F. Machicao, A. Peter, H. Staiger, H.U. Haring, H. Grallert, M. Campillos, H. Maier, H. Fuchs, V. Gailus-Durner, T. Werner, and M. Hrabe de Angelis, Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nat Commun, 2018. 9(1): p. 288.
27. Moore, B.A., B.C. Leonard, L. Sebbag, S.G. Edwards, A. Cooper, D.M. Imai, E. Straiton, L. Santos, C. Reilly, S.M. Griffey, L. Bower, D. Clary, J. Mason, M.J. Roux, H. Meziane, Y. Herault, C. McKerlie, A.M. Flenniken, L.M.J. Nutter, Z. Berberovic, C. Owen, S. Newbigging, H. Adissu, M. Eskandarian, C.W. Hsu, S. Kalaga, U. Udensi, C. Asomugha, R. Bohat, J.J. Gallegos, J.R. Seavitt, J.D. Heaney, A.L. Beaudet, M.E. Dickinson, M.J. Justice, V. Philip, V. Kumar, K.L. Svenson, R.E. Braun, S. Wells, H. Cater, M. Stewart, S. Clementson-Mobbs, R. Joynson, X. Gao, T. Suzuki, S. Wakana, D. Smedley, J.K. Seong, G. Tocchini-Valentini, M. Moore, C. Fletcher, N. Karp, R. Ramirez-Solis, J.K. White, M.H. de Angelis, W. Wurst, S.M. Thomasy, P. Flicek, H. Parkinson, S.D.M. Brown, T.F. Meehan, P.M. Nishina, S.A. Murray, M.P. Krebs, A.M. Mallon, K.C.K. Lloyd, C.J. Murphy, and A. Moshiri, Identification of genes required for eye development by high-throughput screening of mouse knockouts. Commun Biol, 2018. 1: p. 236.
28. Ma, H., C. Liu, B. Shi, Z. Zhang, R. Feng, M. Guo, L. Lu, S. Shi, X. Gao, W. Chen, and L. Sun, Mesenchymal Stem Cells Control Complement C5 Activation by Factor H in Lupus Nephritis. EBioMedicine, 2018. 32: p. 21-30.
29. Luan, X.R., X.L. Chen, Y.X. Tang, J.Y. Zhang, X. Gao, H.P. Ke, Z.Y. Lin, and X.N. Zhang, CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse. Mol Ther Nucleic Acids, 2018. 12: p. 220-228.
30. Lu, K., T.S. Shi, S.Y. Shen, W.L. Lu, J. Wu, K.J. Zhang, X.B. Zhu, Y. Shi, X.L. Liu, F. Yu, L. Li, H.J. Teng, X. Gao, H.X. Ju, W. Wang, C.J. Li, Q. Jiang, and B. Xue, Egr1 deficiency disrupts dynamic equilibrium of chondrocyte extracellular matrix through PPARgamma/RUNX2 signaling pathways. Am J Transl Res, 2018. 10(6): p. 1620-1632.
31. Lu, K., T. Shi, L. Li, K. Zhang, X. Zhu, S. Shen, F. Yu, H. Teng, X. Gao, H. Ju, W. Wang, and Q. Jiang, Zhuangguguanjie formulation protects articular cartilage from degeneration in joint instability-induced murine knee osteoarthritis. Am J Transl Res, 2018. 10(2): p. 411-421.
32. Lin, Z., F. Liu, P. Shi, A. Song, Z. Huang, D. Zou, Q. Chen, J. Li, and X. Gao, Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C. Stem Cell Res Ther, 2018. 9(1): p. 47.
33. Lai, B., J. Zou, Z. Lin, Z. Qu, A. Song, Y. Xu, and X. Gao, Haploinsufficiency of hnRNP U Changes Activity Pattern and Metabolic Rhythms. Am J Pathol, 2018. 188(1): p. 173-183.
34. Geng, L., S. Wang, X. Li, D. Wang, H. Chen, J. Chen, Y. Sun, W. Chen, G. Yao, X. Gao, W. Chen, S. Shi, X. Feng, and L. Sun, Association between Type I interferon and depletion and dysfunction of endothelial progenitor cells in C57BL/6 mice deficient in both apolipoprotein E and Fas ligand. Curr Res Transl Med, 2018. 66(3): p. 71-82.
35. Geng, L., X. Tang, K. Zhou, D. Wang, S. Wang, G. Yao, W. Chen, X. Gao, W. Chen, S. Shi, N. Shen, X. Feng, and L. Sun, MicroRNA-663 induces immune dysregulation by inhibiting TGF-beta1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Cell Mol Immunol, 2018.
36. Dai, J., S. Zhou, Q. Ge, J. Qin, D. Chen, Z. Xu, D. Shi, J. Li, H. Ju, Y. Cao, M. Zheng, C.J. Li, X. Gao, H. Teng, and Q. Jiang, Bi-directional regulation of cartilage metabolism by inhibiting BET proteins-analysis of the effect of I-BET151 on human chondrocytes and murine joints. J Orthop Surg Res, 2018. 13(1): p. 118.
37. Chen, Q., P. Shi, Y. Wang, D. Zou, X. Wu, D. Wang, Q. Hu, Y. Zou, Z. Huang, J. Ren, Z. Lin, and X. Gao, GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity. J Mol Cell Biol, 2018.
38. Wang, Q., S. Jiang, A. Song, S. Hou, Q. Wu, L. Qi, and X. Gao, HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a. Onco Targets Ther, 2017. 10: p. 4753-4763.
39. Song, A., S. Jiang, Q. Wang, J. Zou, Z. Lin, and X. Gao, JMJD3 Is Crucial for the Female AVPV RIP-Cre Neuron-Controlled Kisspeptin-Estrogen Feedback Loop and Reproductive Function. Endocrinology, 2017. 158(6): p. 1798-1811.
40. Meehan, T.F., N. Conte, D.B. West, J.O. Jacobsen, J. Mason, J. Warren, C.K. Chen, I. Tudose, M. Relac, P. Matthews, N. Karp, L. Santos, T. Fiegel, N. Ring, H. Westerberg, S. Greenaway, D. Sneddon, H. Morgan, G.F. Codner, M.E. Stewart, J. Brown, N. Horner, M. Haendel, N. Washington, C.J. Mungall, C.L. Reynolds, J. Gallegos, V. Gailus-Durner, T. Sorg, G. Pavlovic, L.R. Bower, M. Moore, I. Morse, X. Gao, G.P. Tocchini-Valentini, Y. Obata, S.Y. Cho, J.K. Seong, J. Seavitt, A.L. Beaudet, M.E. Dickinson, Y. Herault, W. Wurst, M.H. de Angelis, K.C.K. Lloyd, A.M. Flenniken, L.M.J. Nutter, S. Newbigging, C. McKerlie, M.J. Justice, S.A. Murray, K.L. Svenson, R.E. Braun, J.K. White, A. Bradley, P. Flicek, S. Wells, W.C. Skarnes, D.J. Adams, H. Parkinson, A.M. Mallon, S.D.M. Brown, and D. Smedley, Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Nat Genet, 2017. 49(8): p. 1231-1238.
41. Li, X., Y. Liu, Y. Wang, J. Liu, X. Li, H. Cao, X. Gao, and S.J. Zheng, Negative Regulation of Hepatic Inflammation by the Soluble Resistance-Related Calcium-Binding Protein via Signal Transducer and Activator of Transcription 3. Front Immunol, 2017. 8: p. 709.
42. Li, F., X. Hao, Y. Chen, L. Bai, X. Gao, Z. Lian, H. Wei, R. Sun, and Z. Tian, The microbiota maintain homeostasis of liver-resident gammadeltaT-17 cells in a lipid antigen/CD1d-dependent manner. Nat Commun, 2017. 7: p. 13839.
43. Karp, N.A., J. Mason, A.L. Beaudet, Y. Benjamini, L. Bower, R.E. Braun, S.D.M. Brown, E.J. Chesler, M.E. Dickinson, A.M. Flenniken, H. Fuchs, M.H. Angelis, X. Gao, S. Guo, S. Greenaway, R. Heller, Y. Herault, M.J. Justice, N. Kurbatova, C.J. Lelliott, K.C.K. Lloyd, A.M. Mallon, J.E. Mank, H. Masuya, C. McKerlie, T.F. Meehan, R.F. Mott, S.A. Murray, H. Parkinson, R. Ramirez-Solis, L. Santos, J.R. Seavitt, D. Smedley, T. Sorg, A.O. Speak, K.P. Steel, K.L. Svenson, S. Wakana, D. West, S. Wells, H. Westerberg, S. Yaacoby, and J.K. White, Prevalence of sexual dimorphism in mammalian phenotypic traits. Nat Commun, 2017. 8: p. 15475.
44. Fu, G., Q. Xu, Y. Qiu, X. Jin, T. Xu, S. Dong, J. Wang, Y. Ke, H. Hu, X. Cao, D. Wang, H. Cantor, X. Gao, and L. Lu, Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med, 2017. 214(5): p. 1453-1469.
45. Bowl, M.R., M.M. Simon, N.J. Ingham, S. Greenaway, L. Santos, H. Cater, S. Taylor, J. Mason, N. Kurbatova, S. Pearson, L.R. Bower, D.A. Clary, H. Meziane, P. Reilly, O. Minowa, L. Kelsey, G.P. Tocchini-Valentini, X. Gao, A. Bradley, W.C. Skarnes, M. Moore, A.L. Beaudet, M.J. Justice, J. Seavitt, M.E. Dickinson, W. Wurst, M.H. de Angelis, Y. Herault, S. Wakana, L.M.J. Nutter, A.M. Flenniken, C. McKerlie, S.A. Murray, K.L. Svenson, R.E. Braun, D.B. West, K.C.K. Lloyd, D.J. Adams, J. White, N. Karp, P. Flicek, D. Smedley, T.F. Meehan, H.E. Parkinson, L.M. Teboul, S. Wells, K.P. Steel, A.M. Mallon, and S.D.M. Brown, A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat Commun, 2017. 8(1): p. 886.
46. Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA (2016) High-throughput discovery of novel developmental phenotypes. Nature, 537:508-514.
47. Hou S, Xian L, Shi P, Li C, Lin Z*, Gao X* (2016) The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice. Sci Rep, 6:26735.
48. Jiang H, Shi H, Sun M, Wang Y, Meng Q, Guo P, Cao Y, Chen J, Gao X, Li E, Liu J* (2016) PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense. J Immunol, 197:2880-2890.
49. Jiang S, Wang Q, Huang Z, Song A, Peng Y, Hou S, Guo S, Zhu W, Yan S, Lin Z*, Gao X* (2016) Gastric Bypass Surgery Reverses Diabetic Phenotypes in Bdnf-Deficient Mice. Am J Pathol, 186:2117-2128.
50. Lai SS, Zhao DD, Cao P, Lu K, Luo OY, Chen WB, Liu J, Jiang EZ, Yu ZH, Lee G, Li J, Yu DC, Xu XJ, Zhu MS, Gao X*, Li CJ*, Xue B* (2016) PP2Acalpha positively regulates the termination of liver regeneration in mice through the AKT/GSK3beta/Cyclin D1 pathway. J Hepatol, 64(2):352-360.
51. Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, Fu T, Kong Y, Zhou Q, Vega RB, Zhu MS, Kelly DP, Gao X, Gan Z* (2016) Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med, 8:1212-1228.
52. Lyu YS, Shi PL, Chen XL, Tang YX, Wang YF, Liu RR, Luan XR, Fang Y, Mei RH, Du ZF, Ke HP, Matro E, Li LE, Lin ZY, Zhao J, Gao X, Zhang XN* (2016) A Small Indel Mutant Mouse Model of Epidermolytic Palmoplantar Keratoderma and Its Application to Mutant-specific shRNA Therapy. Mol Thera Nuc Acids, 5:e299.
53. Tang A, Shi P, Song A, Zou D, Zhou Y, Gu P, Huang Z, Wang Q, Lin Z*, Gao X* (2016) PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte. Cell Cycle, 15:1450-1461.
54. Wang X, Li MM, Zhao J, Li S, MacDonald MR, Rice CM, Gao X, Gao G* (2016) Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance. J Virol, 90:10247-10258.
55. Chen W, Huang Z, Jiang X, Li C, *Gao X (2016) Overexpression of myeloid differentiation protein 88 in mice induces mild cardiac dysfunction, but no deficit in heart morphology. Braz J Med Biol Res. 49: e4794
56. Dong D, Li L, Gu P, Jin T, Wen M, Yuan C, Gao X, Liu C, Zhang Z (2015) Profiling metabolic remodeling in PP2Acα deficiency and chronic pressure overload mouse hearts. FEBS Lett. 589:3631-9
57. Gao YQ, Chen X, Wang P, Lu L, Zhao W, Chen C, Chen CP, Tao T, Sun J, Zheng YY, Du J, Li CJ, Gan ZJ, Gao X, Chen HQ, Zhu MS (2015) Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance. Proc Natl Acad Sci U S A. 112:13627-32
58. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH (2015) Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 195:3546-56
59. Li L, Zeng Z, Qi Z, Wang X, Gao X, Wei H, Sun R, Tian Z (2015) Natural Killer Cells-Produced IFN-γ Improves Bone Marrow-Derived Hepatocytes Regeneration in Murine Liver Failure Model. Sci Rep. 5:13687
60. Liu R, Li X, Zhang Z, Zhou M, Sun Y, Su D, Feng X, Gao X, Shi S, Chen W, Sun L (2015) Allogeneic mesenchymal stem cells inhibited T follicular helper cell generation in rheumatoid arthritis. Sci Rep. 5:12777.
61. Tao W, Wu J, Xie BX, Zhao YY, Shen N, Jiang S, Wang XX, Xu N, Jiang C, Chen S, Gao X, Xue B, Li CJ (2015) Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway. J Biol Chem. 290(33):20086-97
62. Zou Q, Wang X, Liu Y, Ouyang Z, Long H, Wei S, Xin J, Zhao B, Lai S, Shen J, Ni Q, Yang H, Zhong H, Li L, Hu M, Zhang Q, Zhou Z, He J, Yan Q, Fan N, Zhao Y, Liu Z, Guo L, Huang J, Zhang G, *Ying J, *Lai L, *Gao X (2015) Generation of gene-target dogs using CRISPR/Cas9 system. J Mol Cell Biol 7:580-3
63. Shi P, Tang A, Xian L, Hou SY, Zou D, Lv Y, Huang Z, Wang QH, Song AY, Lin Z and *Gao X (2015) Loss of conserved Gsdma3 self-regulation causes autophagy and cell death. Biochem J, 468:325-336
64. Xian L, Hou SY, Huang Z, Tang A, Shi P, Wang Q, Lin ZY, Guo SY and *Gao X (2015) Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity. Aging 7:223-32.
65. Gao M, Wang X, Zhang X, Ha T, Ma H, Liu L, Kalbfleisch JH, Gao X, Kao RL, Williams DL, Li C (2015) Attenuation of cardiac dysfunction in polymicrobial sepsis by microRNA-146a is mediated via targeting of IRAK1 and TRAF6 expression. J Immunol. 195:672-82
66. Gu Y, He Y, Zhang X, Shi Y, Yang Q, Yu L, Sun Z, Zhang H, Wang J, Gao X, Wang J (2015) Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice. Mol Reprod Dev. 82:475-88
67. Chen H, Shi B, Feng X, Kong W, Chen W, Geng L, Chen J, Liu R, Li X, Chen W, Gao X, Sun L (2015) Leptin and NAP2 promote mesenchymal stem cell senescence through activation of PI3K/Akt pathway in patients with systemic lupus erythematosus. Arthritis Rheumatol. 67(9):2383-93
68. Sun Y, Deng W, Geng L, Zhang L, Liu R, Chen W, Yao G, Zhang H, Feng X, Gao X, Sun L (2015) Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res. 2015:284215
69. Hou H, Zheng K, Wang G, Ikegawa S, Zheng M, Gao X, Qin J, Teng H, Jiang Q (2015) Influence of intra-articular administration of trichostatin a on autologous osteochondral transplantation in a rabbit model. Biomed Res Int. 2015:470934
70. Qi X, *Gao X (2015) Towards a better understanding of mouse and human diseases-International Mouse Phenotyping Consortium. Sci China Life Sci. 58:392-5.
71. Qu Z, Wang X, Liu D, Gao X, Xu Y (2015) Inactivation of Cipc alters the expression of Per1 but not circadian rhythms in mice. Sci China Life Sci. 58:368-72
72. Xu N, Guan S, Chen Z, Yu Y, Xie J, Pan FY, Zhao NW, Liu L, Yang ZZ, Gao X, Xu B, Li CJ (2015) The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure. J Pathol. 235:672-85
73. Zou J, Xiong X, Lai B, Sun M, Tu X, *Gao X (2015) Glucose metabolic abnormality is associated with defective mineral homeostasis in skeletal disorder mouse model. Sci China Life Sci. 58:359-67
74. Yu P, Zhang Y, Li C, Li Y, Jiang S, Zhang X, Ding Z, Tu F, Wu J, Gao X, Li L (2015) Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure. J Cell Mol Med. 19:1710-9
75. Sun Y, Wang C, Hao Z, Dai J, Chen D, Xu Z, Shi D, Mao P, Teng H, Gao X, Hu Z, Shen H, Jiang Q (2015) A common variant of ubiquinol-cytochrome c reductase complex is associated with DDH. PLoS One. 10:e0120212
76. Yang J, Lai B, Xu A, Liu Y, Li X, Zhao Y, Li W, Ji M, Hu G, Gao X, Gao J (2015)Maged1 co-interacting with CREB through a hexapeptide repeat domain regulates learning and memory in mice. Mol Neurobiol. 51:8-18.
77. Huang Z, Ruan H-B, Xian L, Chen W, Jiang S, Song A, Wang Q, Shi P, Gu X, *Gao X (2014) The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure. Nature Communications 5: 4282.
78. Huang Z, Ruan H, Zhang Z, Chen W, Lin Z, Zeng H, *Gao X (2014) Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice. Am J Path 184: 122-132
79. Qi X, Xu JY, Gu PY, Yang X, *Gao X (2014) PTEN in smooth muscle cells is essential for colonic immune homeostasis. Int J Biochem & Cell Biol 53: 108-114
80. Ren K, Yuan J, Yang M, Gao X, Ding X, Zhou J, Hu X, Cao J, Deng X, Xiang S, Zhang J. KCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic development. PLoS One. 2014 Nov 17;9(11):e112275
81. Che N, Li X, Zhang L, Liu R, Chen H, Gao X, Shi S, Chen W, Sun L. Impaired B cell inhibition by lupus bone marrow mesenchymal stem cells is caused by reduced CCL2 expression. J Immunol. 2014 Nov 15;193(10):5306-14.
82. Qi Z, Li L, Wang X, Gao X, Wang X, Wei H, Zhang J, Sun R, Tian Z. Bone marrow transplantation concurrently reconstitutes donor liver and immune system across host species barrier in mice. PLoS One. 2014 Sep 5;9(9):e106791.
83. Ma B, Cao W, Li W, Gao C, Qi Z, Zhao Y, Du J, Xue H, Peng J, Wen J, Chen H, Ning Y, Huang L, Zhang H, Gao X, Yu L, Chen YG. Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation. Cell Res. 2014 Aug;24(8):912-24.
84. Wang J, Li F, Sun R, Gao X, Wei H, Tian Z. Klebsiella pneumoniae alleviates influenza-induced acute lung injury via limiting NK cell expansion. J Immunol. 2014 Aug 1;193(3):1133-41.
85. Long L, Deng Y, Yao F, Guan D, Feng Y, Jiang H, Li X, Hu P, Lu X, Wang H, Li J, Gao X, Xie D. Recruitment of phosphatase PP2A by RACK1 adaptor protein deactivates transcription factor IRF3 and limits type I interferon signaling. Immunity. 2014 Apr 17;40(4):515-29.
86. Zhang Z, Hao CJ, Li CG, Zang DJ, Zhao J, Li XN, Wei AH, Wei ZB, Yang L, He X, Zhen XC, Gao X, Speakman JR, Li W. Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons. PLoS Genet. 2014 Feb 13;10(2):e1004124.
87. Wang X, Ha T, Zou J, Ren D, Liu L, Zhang X, Kalbfleisch J, Gao X, Williams D, Li C. MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6. Cardiovasc Res. 2014 Jun 1;102(3):385-95.