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1. Gao H-M*, Gao Y, Tu DZ, Liu Y, Zhou H, and Hong JS (2018) In_ ammation-mediated Neurodegeneration: Models, Mechanisms, and Therapeutic Interventions for neurodegenerative Diseases. In: Inflammation—From Molecular and Cellular Mechanisms to the Clinic (Jean-Marc Cavaillon & Mervyn Singer, ed). pp1255-1278. Wiley-VCH
2. Gao H-M*, Tu DZ, Gao Y, Liu QY, Yang R, Liu Y, Guan T, and Hong J-S (2017) Roles of microglia in in_ ammation-mediated neurodegeneration: Models, mechanisms, and therapeutic interventions for Parkinson’s disease In: Advances in Neurotoxicology (Michael Aschner and Lucio Costa, ed), pp185-209. Elsevier
3. Yinxi Wang, Dan Liu, Huifeng Zhang, Yixin Wang, Ling Wei, Yutong Liu, Jieying Liao, Hui-Ming Gao, Hui Zhou (2017) Ultra_ ne carbon particles promote rotenone-induced dopamine neuronal loss through activating microglial NADPH oxidase. Toxicology and Applied Pharmacology 322: 51-591
4. Chu CH, Wang S, Li CL, Chen SH, Hu CF, Chung YL, Chen SL, Wang Q, Lu RB, Gao H-M*, Hong JS (2016) Neurons and astroglia govern microglial endotoxin tolerance through macrophage colony-stimulating factor receptor-mediated ERK1/2 signals. Brain, Behavior, and Immunity 55: 260–272 (*Correspondence).
5. Chu CH, Chen SH, Wang Q, Langenbach R, Li H, Zeldin D, Chen SL, Wang S, Gao H-M*, Lu RB*, Hong JS (2015) PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition. Molecular Neurobiology 52(1):587-600. (*Correspondence).
6. Zhou H, Liao J, Aloor J, Nie H, Wilson B, Fessler M, Gao H-M*, Hong J-S (2013) CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses. Journal of Immunology 190:115-125 (*Correspondence).
7. Mattison HA, Nie H, Gao H-M, Zhou H, Hong J-S, and Zhang J (2013) Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice. Journal of Neuroimmunology 257(1-2):110-5
8. Gao H-M*, Zhou H, Hong J-S (2012) NADPH oxidases: novel therapeutic targets for neurodegenerative diseases. Trends in Pharmacological Sciences 33(6): 295-303 (*Correspondence).
9. Zhou H, Zhang F, Chen S-H, Zhang D, Wilson B, Hong J-S, Gao H-M* (2012) Rotenone activates phagocyte NADPH oxidase through binding to its membrane subunit gp91phox. Free Radical Biology & Medicine 52: 303–313. (*Correspondence).
10. Zhang F, Zhou H, Wilson, B, Shi J-S, Hong J-S, and Gao H-M* (2012) Fluoxetine protects neurons against microglial activation-mediated neurotoxicity. Parkinsonism & Relat Disord. 18 Suppl 1 pp. S213-7 (*Correspondence).
11. Wang QS, Zhou H, Gao H-M, Chen S-H, Chu C-H, Wilson B, Hong J-S (2012) Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. Journal of Neuroinflammation. 9(1):32.
12. Gao H-M* and Hong J-S (2011) Gene–environment interactions: key to unraveling the mystery of Parkinson’s disease. Progress in Neurobiology 94:1–19. (*Correspondence).
13. Gao H-M*, Zhou H, Zhang F, Wilson B, Kam W, Hong J-S (2011) HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration Journal Neuroscience. 31(3):1081–1092 (*Correspondence).
14. Gao H-M*, Zhang F, Zhou H, Kam W, Wilson B, Hong J-S (2011) Neuroinflammation and alpha-synuclein dysfunction potentiate each other driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. Environmental Health Perspectives 119 (6): 807-814 (*Correspondence).
15. Flood PM, Qian L, Peterson L, Zhang F, Shi J-S, Gao H-M, Hong J-S (2011) Transcritional factor NF-kB as s target for therapy in Parkinson’s disease. Parkinson’s Disease 2011:216298.
16. Hu X, Zhou H, Zhang D, Yang S, Qian L, Wu H-M, Chen PS, Wilson B, Gao H-M, Lu RB, Hong J-S (2011) Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation. Journal of Neuroimmune Pharmacology. 7(1):187-201
17. Zhang F, Qian L, Flood PM, Shi J-S, Hong J-S, and Gao H-M* (2010) Inhibition of IκB kinase-β (IKK-β) Protects Dopamine Neurons against Lipopolysaccharide-Induced Neurotoxicity. The Journal of Pharmacology and Experimental Therapeutics 333(3):822-33 (*Correspondence).
18. Zhang F, Shi J-S, Zhou H, Wilson BC, Hong J-S, and Gao H-M* (2010) Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions. Molecular Pharmacology 78(3):466-477 (*Correspondence).
19. Schug TT, Xu Q, Gao H-M, Peres-da-Silva A, David DW, Fessler MB., Purushotham A, and Li X (2010) Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress. Molecular and Cellular Biology. 30(19):4712-21
20. Gao H-M, Kotzbauer PT, Uryu K, Leight S, Trojanowski JQ, Lee VM. (2008) Neuroinflammation and oxidation/nitration of α-synuclein linked to dopaminergic neurodegeneration. J. Neurosci. 28(30):7687–7698
21. Gao H-M*, Hong J-S (2008) Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Trends in Immunology 29: 357-365 ** cover illustration (*Correspondence).
22. Zhang D, Hu X, Wei S-J, Liu J, Gao H-M, Qian L, Wilson, B, Liu G and Hong JS (2008) Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity. J. Neuroinflammation 5:21-33
23. Hu X, Zhang D, Pang h, Caudle M W, Li, Y, Gao H-M, Liu Y, Qian L, Wilson, B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS (2008) Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease. J. Immunology 181(10):7194-204
24. Zhang W, Qin L, Wang T, Wei SJ, Gao H-M, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong J-S. (2006) 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. FASEB J. 19(3):395-397
25. Zhang W, Wang T, Qin L, Gao H-M, Wilson B, Ali S, Zhang WQ, Hong J-S, Liu B (2004) Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. FASEB J. 18(3):589-91
26. Du Xinlu, Gao Huiming, Zhao Jie, Liu Xueyuan, Zhang Wanqin(2005)The change of Bcl-2 protein expression in area tempestas of seizure sensitive rats. Chinese Journal of Neuroanatomy 21(2): 185-189
27. Du Xinlu, Gao Huiming, Zhao Jie, Liu Xueyuan, Zhang Wanqin(2004)The change of k opioid receptors and NR2B immunoreactivity in area tempestas of seizure sensitive rats. Chinese Journal of Neuroanatomy 05: 463-67
28. Liu H, Gao H-M, Zhang WQ, Tang YY, Song HS (2004) Effects of chronic administration of PL017 and beta-funaltrexamine hydrochloride on susceptibility of kainic acid-induced seizures in rats. Acta Physiologica Sinica. 56(1):101-6
29. Liu Hui, Gao Huiming, Yang Donghui, Peng Yan, Song Aihong; Zhang Wanqin (2002) The role of mu-opioid receptors in seizure susceptibility induced by kainic acid. Chinese Journal of Neurology 35(3):147-150
30. Gao H-M*, Liu B, Hong J-S (2003) Critical role of microglial NADPH oxidase in rotenone-induced dopaminergic neurodegeneration. Journal Neuroscience 23 (15):6181-6187 (*Correspondence).
31. Gao H-M*, Liu B, Zhang WQ, Hong J-S (2003) Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson’s disease. FASEB J. 17(11):1957-+; DOI: 10.1096/fj.03-0203fje (*Correspondence).
32. Gao H-M*, Liu B, Zhang WQ, Hong J-S (2003) Novel anti-inflammatory therapy for Parkinson’s disease. Trends in Pharmacological Sciences 24 (8):395-401 (*Correspondence).
33. Gao H-M, Liu B, Zhang WQ, Hong J-S (2003) Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson’s disease. FASEB J. 17(13):1954-+; DOI: 10.1096/fj.03-0109fje
34. Gao H-M, Hong J-S, Zhang WQ, Liu B (2003) Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson’s disease. Journal Neuroscience 23(4):1228-1236
35. Liu B, Gao H-M, Hong J-S (2003) Parkinson’s disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuro-inflammation. Environmental Health Perspectives 111:1065-1073
36. Gao H-M, Hong J-S, Zhang WQ, Liu B (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. Journal Neuroscience 22:782-790
37. Gao H-M, Jiang JW, Wilson BC, Zhang WQ, Hong J-S, Liu B (2002) Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson’s disease. J. Neurochem. 81:1285-1297.
38. Liu B, Gao H-M, Jeohn GH, Cooper CP, Hong J-S (2002) Role of nitric oxide in inflammation-mediated neurodegeneration. Annals of the New York Academy of Sciences 962:318-331
39. Liu B, Wang K, Gao H-M, Mandavilli B, Wang JY, Hong J-S (2001) Molecular consequences of activated microglia in the brain: overactivation induces apoptosis. J. Neurochem. 77:182-189