Horrocks, Nicholas - University of Cambridge

研究领域

Disease and infection are a constant hazard for all organisms, but variation in immunity among individuals, populations and species, is widespread. My research investigates the causes and consequences of variation in immune defences. Using methods that allow me to study the immune function of animals –– particularly birds –– in their natural, free-living settings, I try to relate these measures of immunity to aspects of physiology, life history and the habitats that individuals live in. In particular I am interested in trying to relate variation in immunity to differences in disease pressures between environments

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Schroeder, J., Dugdale H.L., Radersma R., et al. & Horrocks, N.P.C. (2013) Fewer invited talks by women in evolutionary biology symposia. J. Evol. Biol. (This paper was widely discussed online, including by Science, The Telegraph, The Times, and Athene Donald’s blog). Horrocks N.P.C., Vollrath, F., & Dicko C. (2013) The silkmoth cocoon as humidity trap and waterproof barrier. Comp. Biochem. Physiol. A 164: 645-652. Matson K.D., Horrocks N.P.C., Tieleman B.I., & Haase E. (2012) Intense flight and endotoxin injection elicit similar effects on leukocyte distributions but dissimilar effects on plasma-based immunological indices in pigeons. J. Exp. Biol. 215: 3734-3741. Horrocks N.P.C., Hegemann A., Matson K.D., Hine K., Jaquier S., Tinbergen, J.M., Shobrak M., Williams J.B., & Tieleman B.I. (2012) Immune indexes of larks from desert and temperate regions show weak associations with life history, but stronger links to environmental variation in microbial abundance. Physiol. Biochem. Zool. 85: 504-515. Matson K.D., Horrocks N.P.C., Versteegh M.A., & Tieleman B.I. (2012) Baseline haptoglobin concentrations are repeatable and predictive of certain aspects of a subsequent experimentally-induced inflammatory response. Comp. Biochem. Physiol. A 162: 7-15. Horrocks N.P.C., Matson K.D., Shobrak M., & Tieleman B.I. (2012) Seasonal patterns in immune indices reflect microbial loads on birds but not microbes in the wider environment. Ecosphere 3: art. 19. Horrocks N.P.C., Matson K.D., & Tieleman B.I. (2011) Pathogen pressure puts immune defense into perspective. Integr. Comp. Biol. 51: 563-576. Horrocks N.P.C., Tieleman B.I., & Matson K.D. (2011) A simple assay for measurement of ovotransferrin – a marker of inflammation and infection in birds. Methods Ecol. Evol. 2: 518-523. van de Crommenacker J., Horrocks N.P.C., Versteegh M.A., Komdeur J., Tieleman B.I., & Matson K.D. (2010) Effects of immune supplementation and immune challenge on oxidative status and physiology in a model bird: Implications for ecologists. J. Exp. Biol. 213: 3527-3535. Horrocks N., Perrins C., & Charmantier A. (2009) Seasonal changes in male and female bill knob size in the Mute swan Cygnus olor. J. Avian Biol. 40: 511-519. Horrocks N., Pounder R. (2006) Who’s for five nine-hour shifts a week? Clin. Med. 6: 440-442. Horrocks N., Pounder R., RCP Working Group. (2006) Working the night shift: preparation, survival and recovery – a guide for junior doctors. Clin. Med. 6: 61-67.