储剑虹 - 苏州大学 - 造血干细胞移植研究所

个人简介

教育背景 1997年-2002年安徽医科大学临床医学学士 2002年-2005年复旦大学药理学硕士 2005年-2008年香港中文大学解剖学博士工作经 2009年-2012年香港浸会大学中医药学院博士后 2012年-2015年美国俄亥俄州立大学内科血液学部门博士后 2015年10月-至今苏州大学造血干细胞移植研究所特聘教授

近期论文

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Jiang D, Tian X, Bian X, Zhu T, Qin H, Zhang R, Xu Y, Pan Z, Huang H, Fu J, Wu D#, Chu J#. T cells redirected against Igβ for the immunotherapy of B cell lymphoma. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0607-5. (2020 Mar;34(3):821-830. (# Corresponding author)) Wang Y*, Chu J*, Yi P*, Dong W, Saultz J, Wang Y, Wang H, Scoville S, Zhang J, Wu LC, Deng Y, He X, Mundy-Bosse B, Freud AG, Wang LS, Caligiuri MA, Yu J. SMAD4 promotes TGF-β-independent NK cell homeostasis and maturation and antitumor immunity. Journal of Clinical Investigation. 2018 Nov 1;128(11):5123-5136. (* Co-first author) Deng Y*, Kerdiles Y*, Chu J*, Yuan S*, Wang Y, Chen X, Mao H, Zhang L, Zhang J, Hughes T, Deng Y, Zhang Q, Wang F, Zou X, Liu CG, Freud AG, Li X, Caligiuri MA, Vivier E, Yu J. Transcription factor Foxo1 is a Negative Regulator of Natural killer Cell Maturation and Function. Immunity. 2015; 42(17):457-470. (* Co-first author) Chu J, Deng Y, Benson DM, He S, Hughes T, Zhang J, Peng Y, Mao H, Yi L, Ghoshal K, He X, Devine SM, Zhang X, Caligiuri MA, Hofmeister CC, Yu J. CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma. Leukemia. 2014; 28(4):917-27. Chu J, He S, Deng Y, Zhang J, Peng Y, Hughes T, Yi L, Kwon CH, Wang QE, Devine SM, He X, Bai XF, Hofmeister CC, Yu J. Genetic Modification of T cells Redirected towards CS1 Enhances Anti-Myeloma activity. Clinical Cancer Research. 2014;20(15): 3989-4000. He S, Chu J, Wu LC, Mao H, Peng Y, Alvarez-Breckenridge CA, Hughes T, Wei M, Zhang J, Yuan S, Sandhu S, Vasu S, Benson DM Jr, Hofmeister CC, He X, Ghoshal K, Devine SM, Caligiuri MA, Yu J. MicroRNAs Activate Natural Killer Cells through Toll-like Receptor Signaling. Blood. 2013;121(23):4663-71.