MacVinish, Lesley - University of Cambridge - Department of Pharmacology

个人简介

I read Biology at Aberdeen University (1975–1979) where I also studied for my PhD (1979-1983). On completion of my doctorate I moved to Cambridge and worked as a postdoctoral researcher for many years in the laboratory of Professor Alan Cuthbert in the Departments of Pharmacology and Medicine. Our research focussed on epithelial physiology and pharmacology, with a specific interest in the genetic disease, cystic fibrosis. I returned to Pharmacology in 2004 to take up the post of Senior Teaching Associate where I am the departmental teaching coordinator as well as having a full teaching load. In recognition of my contribution to outstanding teaching within the Department, I was awarded the a Pilkington Prize for Teaching in 2013 (http://www.cam.ac.uk/for-staff/news/2013-pilkington-prizes). I am also the Graduate Admissions Tutor for the Department and Joint Chair of the Cambridge BBSRC Doctoral Training Partnership programme (bbsrcdtp.lifesci.cam.ac.uk) In 2012 I was appointed as Deputy Director of Education for the Faculty of Biology in addition to my Departmental role. I have special teaching responsibility for the Medical and Veterinary Science Tripos and, as such, serves on a number of University Committees to support this role.

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Murthy M, Pedemonte N, MacVinish L, Galietta L, Cuthbert A. 4-chloro-benzo[F]isoquinoline (CBIQ) is a novel activator of CFTR chloride channels at nanomolar concentrations. (2005). European J Pharmacol, 516(2):118-24 MacVinish L.J., Cope G., Ropenga A. & Cuthbert A.W. Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR. (2007) Br J Pharmacol. Apr;150(8):1055-65 Edmond C.Y. U, Xin J. Zhao & L J MacVinish (2005) The effect of sildenafil on chloride secretion in normal and transgenic murine cystic fibrosis colonic epithelia. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/ Vol3 Issue2 abst126P