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个人简介

1983 Suzhou Medical University, China, MD 1994 Karolinska Institute, Sweden, PhD (Doctor of Medical Sciences) 1978-1983: MD Suzhou Medical University, China. 1989-1994: PhD Department of Immunpathology,Karolinska Institute, Stockholm, Sweden. 1994-96: Postdoctoral fellow, Department of Clinical Virology, Hudding Hospital, Karolinska Institute 1996-2000: Assistant Professor, and then Associate Professor since 2000, Institute of Cell and Molecular Biology, Lund University, Sweden 2001-2005: Lecturer in Immunology and Biochemistry, Division of Biosciences, Brunel University London 2005-present: Reader in Immunology, Division of Biosciences, Brunel University London

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Liu, M. , Miao, T. , Zhu, H. , Symonds, ALJ. , et al. (2012) 'IL-2–engineered nano-APC effectively activates viral antigen-mediated T cell responses from chronic Hepatitis B virus-infected patients'. Journal of Immunology, 188 (3). pp. 1534 - 1543. doi: 10.4049/?jimmunol.1102709 Li, S. , Symonds, ALJ. , Zhu, B. , Liu, M. , et al. (2011) 'Early growth response gene-2 (Egr-2) regulates the development of B and T cells'. PLoS ONE, 6 (4). doi: 10.1371/journal.pone.0018498 Download publication Sofra, V. , Mansour, S. , Liu, M. , Gao, B. , et al. (2009) 'Antigen-loaded ER microsomes from APC induce potent immune responses against viral infection'. European Journal of Immunology, 39 (1). pp. 85 - 95. doi: 10.1002/eji.200838443 Zhu, B. , Symonds, AL. , Martin, JE. , Kioussis, D. , et al. (2008) 'Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease'. J Exp Med, 205 (10). pp. 2295 - 2307. doi: 10.1084/jem.20080187 Download publication Khalid, S. , Khan, M. , Gorle, CB. , Fraser, K. , et al. (2008) 'MaXlab: A novel application for the cross comparison and integration of biological signatures from microarray studies'. In Silico Biology, 8 (3-4). pp. 363 - 376. Khalid, S. , Grazio, D. , Wang, P. , Liu, X. and Li, S. (2008) 'Designing customised gene expression arrays based on specific biological questions or functions'. Journal of Integrated Design & Process Science, 11 (3). pp. 67 - 81. Khalid, S. , Khan, M. , Symonds, A. , Fraser, K. , et al. (2007) 'CIDA: an integrated software for the design, characterisation and global comparison of microarrays'. J. integrated Bioinformatics, 4 (3). pp. 78. Paulsson, KM. , Jevon, M. , Anderson, P. , Li, S. and Wang, P. (2006) 'The double lysine motif of tapasin is a retrieval signal for retention of unstable MHC class I molecules in the endoplasmic reticulum'. The Journal of Immunology, 176 (12). pp. 7482 - 7488. Anderson, PO. , Manzo, BA. , Sundstedt, A. , Minaee, S. , et al. (2006) 'Persistent antigenic stimulation alters the transcription program in T cells, resulting in antigen-specific tolerance'. European Journal of Immunology, 36 (6). pp. 1374 - 1385. doi: 10.1002/eji.200635883 Download publication Khalid, S. , Fraser, K. , Khan, M. , Wang, P. , et al. (2006) 'Analysing Microarray Data using the Multi-functional Immune Ontounlogiser'. J. integrated Bioinformatics, 3 pp. 25. Anderson, PO. , Sundstedt, A. , Yazici, Z. , Minaee, S. , et al. (2005) 'IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells.'. Journal of immunology (Baltimore, Md. : 1950), 174 (1). pp. 310 - 319. Li, L. , Gronning, LM. , Anderson, PO. , Li, S. , et al. (2004) 'Insulin Induces SOCS-6 Expression and Its Binding to the p85 Monomer of Phosphoinositide 3-Kinase, Resulting in Improvement in Glucose Metabolism'. Journal of Biological Chemistry, 279 (33). pp. 34107 - 34114. doi: 10.1074/jbc.M312672200 Anderson, P. (2003) 'Differential activation of signal transducer and activator of transcription (STAT)3 and STAT5 and induction of suppressors of cytokine signalling in Th1 and Th2 cells'. International Immunology, 15 (11). pp. 1309 - 1317. doi: 10.1093/intimm/dxg130 Chen, S. , Anderson, PO. , Li, L. , Sj?gren, HO. , et al. (2003) 'Functional association of cytokine-induced SH2 protein (CIS) and protein kinase C in activated T cells'. International Immunology, 15 (3). pp. 403 - 409. doi: 10.1093/intimm/dxg039 Anderson, P. , Sundstedt, A. , Massey, E. , LI, S. , et al. (2003) 'Differential Activation of Signal Transducers and Activators of Transcription -3 and –5 (STAT)s and Induction of Suppressors Of Cytokine Signaling (SOCS) in T helper (Th) 1 and Th2 cells'. Int Immunol., 15 (11). pp. 1309 - 1317. Paulsson, KM. (2002) 'Association of Tapasin and COPI Provides a Mechanism for the Retrograde Transport of Major Histocompatibility Complex (MHC) Class I Molecules from the Golgi Complex to the Endoplasmic Reticulum'. Journal of Biological Chemistry, 277 (21). pp. 18266 - 18271. doi: 10.1074/jbc.M201388200 Turnquist, HR. , Vargas, SE. , McIlhaney, MM. , Li, S. , et al. (2002) 'Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin'. Tissue Antigens, 59 (1). pp. 18 - 24. doi: 10.1034/j.1399-0039.2002.590104.x Turnquist, HR. , Vargas, SE. , Reber, AJ. , McIlhaney, MM. , et al. (2001) 'A region of tapasin that affects L(d) binding and assembly.'. Journal of immunology (Baltimore, Md. : 1950), 167 (8). pp. 4443 - 4449. Paulsson, KM. , Wang, P. , Anderson, PO. , Chen, S. , et al. (2001) 'Distinct differences in association of MHC class I with endoplasmic reticulum proteins in wild-type, and β2-microglobulin- and TAP-deficient cell lines'. International Immunology, 13 pp. 101 - 111. doi: 10.1093/intimm/13.8.1063 Wang, P. , Anderson, PO. , Chen, S. , Paulsson, KM. , et al. (2001) 'Inhibition of the transcription factors AP-1 and NF-κB in CD4 T cells by peroxisome proliferator-activated receptor γ ligands'. International Immunopharmacology, 1 (4). pp. 803 - 812. doi: 10.1016/S1567-5769(01)00015-7

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