Kill, Ian - Brunel University - Department of Life Sciences, Biomedical Sciences

个人简介

2001- Present: Senior Lecturer in Human Cell Biology. Brunel University London. 1997-2001: Lecturer in Human Cell Biology. Brunel University London. 1995-1997: Lecturer in Zoology. Fixed term contract. University of Dundee. 1994-1995: Post-doctoral research fellow. University of Dundee. MRC. Grantholder. 1991-1994: CRC Post-doctoral research fellow. University of Dundee. Co-applicant. 1990-1991: MRC Post-doctoral research fellow. University of Dundee. Co-applicant. 1986-1989: D. Phil. University of Sussex. 1981-1986: Research Technician, Kennedy Institute of Rheumatology. (Dr. Fiona Watt). 1980-1981: Research Technician, St Mary’s Hospital, Paddington. (Dr. Hanna Braunsberg). 1976-1979: BSc. Portsmouth Polytechnic.

近期论文

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Mehta, IS. , Arican, HD. , Eskiw, CH. , Kill, IR. and Bridger, JM. (2011) 'Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford Progeria syndrome cells.'. Genome Biology: biology for the post-genomic era, 12 (8). doi: 10.1186/gb-2011-12-8-r74 Download publication Bridger, JM. , Eskiw, CH. , Makarov, EM. , Tree, D. and Kill, IR. (2011) 'Progeria Research Day at Brunel University'. Nucleus, 2 (6). pp. 1 - 6. Mehta, IS. , Bridger, JM. and Kill, IR. (2010) 'Progeria, the nucleolus and farnesyltransferase inhibitors.'. Biochem Soc Trans, 38 (Pt 1). pp. 287 - 291. doi: 10.1042/BST0380287 Faragher, RG. and Kill, IR. (2009) 'The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts'. Biogerontology, 10 (3). pp. 285 - 289. doi: 10.1007/s10522-008-9198-7 He, X. , Bridger, JM. and Kill, IR. (2008) 'Hutchinson-Gilford progeria syndrome: Too old, too soon'. Biochemist, 30 (5). pp. 18 - 22. Mehta, IS. , Elcock, LS. , Amira, M. , Kill, IR. and Bridger, JM. (2008) 'Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?'. Biochemical Society Transactions, 36 (Part 6). pp. 1384 - 1388. doi: 10.1042/BST0361384 Pekovic, V. , Kill, IR. , Benham, AM. , Dixon, D. , et al. (2008) 'The functional involvement of lamin A in human ageing: implications for maintenance of proliferation via lamin A redox homeostasis'. JOURNAL OF ANATOMY, 212 (1). pp. 79 - 80. Beard, GS. , Bridger, JM. , Kill, IR. and Tree, DR. (2008) 'Towards a Drosophila model of Hutchinson-Gilford progeria syndrome'. Biochemical Society Transactions, 36 (Part 6). pp. 1389 - 1392. doi: 10.1042/BST0361389 Mehta, IS. , Figgitt, M. , Clements, CS. , Kill, IR. and Bridger, JM. (2007) 'Alterations to nuclear architecture and genome behavior in senescent cells'. Annals of the New York Academy of Sciences, 1100 (Biogerontology Mechanisms and Interventions). pp. 250 - 263. doi: 10.1196/annals.1395.027 Meaburn, KJ. , Cabuy, E. , Bonne, G. , Levy, N. , et al. (2007) 'Primary laminopathy fibroblasts display altered genome organization and apoptosis'. Aging Cell, 6 (2). pp. 139 - 153. doi: 10.1111/j.1474-9726.2007.00270.x Bridger, JM. , Foeger, N. , Kill, IR. and Herrmann, H. (2007) 'The nuclear lamina. Both a structural framework and a platform for genome organization'. FEBS Journal, 274 (6). pp. 1354 - 1361. doi: 10.1111/j.1742-4658.2007.05694.x Al-Baker, EA. , Oshin, M. , Hutchison, CJ. and Kill, IR. (2005) 'Analysis of UV-induced damage and repair in young and senescent human dermal fibroblasts using the comet assay'. Mechanisms of Ageing and Development, 126 (6-7). pp. 664 - 672. doi: 10.1016/j.mad.2004.12.002 Boyle, J. , Kill, IR. and Parris, CN. (2005) 'Heterogeneity of dimer excision in young and senescent human dermal fibroblasts'. Aging Cell, 4 (5). pp. 247 - 255. doi: 10.1111/j.1474-9726.2005.00167.x Al Baker, EA. , Boyle, J. , Harry, R. and Kill, IR. (2004) 'A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation'. Experimental Cell Research, 292 (1). pp. 179 - 186. doi: 10.1016/j.yexcr.2003.09.006 Bridger, JM. and Kill, IR. (2004) 'Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis'. Experimental Gerontology, 39 (5). pp. 717 - 724. doi: 10.1016/j.exger.2004.02.002 Download publication Bridger, JM. , Boyle, S. , Kill, IR. and Bickmore, WA. (2000) 'Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts'. Current Biology, 10 (3). pp. 149 - 152. doi: 10.1016/S0960-9822(00)00312-2 Kill, IR. (1998) 'Ageing research in the UK: Plenty of proliferative potential'. Molecular Medicine Today, 4 (11). pp. 466 - 467. doi: 10.1016/S1357-4310(98)01360-4 Kill, IR. (1998) 'Ageing research in the UK: plenty of proliferative potential. Cellular Senescence: the future of ageing. Oxford, United Kingdom, 16-17 July 1998.'. Molecular medicine today, 4 (11). pp. 466 - 467. Bridger, JM. , Kill, IR. and Lichter, P. (1998) 'Association of pKi-67 with satellite DNA of the human genome in early G(1) cells'. Chromosome Research, 6 (1). pp. 13 - 24. doi: 10.1023/A:1009210206855 Dyer, JA. , Kill, IR. , Pugh, G. , Quinlan, RA. , et al. (1997) 'Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies'. Chromosome Research: the international journal for all aspects of chromosome and nuclear biology, 5 (6). pp. 383 - 394. doi: 10.1023/A:1018496309156