Williams, Alistair - University of Bristol - School of Clinical Sciences

研究领域

Understanding the heterogeneity of humoral autoimmune responses in type 1 diabetes. Characterising changes in pancreas size in diabetes

近期论文

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Williams, G, Long, A, Wilson, I, Aitken, R, Wyatt, R, McDonald, TJ, Wong, S, Hattersley, AT, Williams, A, Bingley, P & Gillespie, K, 2016, ‘Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.’. Williams, A & Elvers, K, 2016, ‘Molecular Methods and Protein Synthesis for Definition of Autoantibody Epitopes.’. in: Kathleen Gillespie (eds) Methods in Molecular Biology. Humana Press Inc., New York, pp. 179-207 Williams, A, Lampasona, V, Michael, S, Mueller, P, Pittman, D, Winter, W, Akolkar, B, Wyatt, R, Brigatti, C, Krause, S & Achenbach, P, 2015, ‘Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes: Improved specificity of autoantibodies to N-terminally truncated GAD’. Diabetes, vol 64., pp. 3239-3246 Ye, J, Long, AE, Pearson, JA, Taylor, H, Bingley, PJ, Williams, AJK & Gillespie, KM, 2015, ‘Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes’. Diabetologia, vol 58., pp. 2284-7 Wyatt, R & Williams, AJK, 2015, ‘Islet Autoantibody Analysis: Radioimmunoassays’. Methods in Molecular Biology. Brorsson, CA, Onengut, S, Chen, W-M, Wenzlau, J, Yu, L, Baker, P, Williams, AJK, Bingley, PJ, Hutton, JC, Eisenbarth, GS, Concannon, P, Rich, SS, Pociot, F & , 2015, ‘Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes’. Diabetes, vol 64., pp. 3017-27 Gillespie, KM, Aitken, RJ, Wilson, I, Williams, AJK & Bingley, PJ, 2013, ‘Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings’. Diabetes. Long, AE, Gillespie, KM, Aitken, RJ, Goode, JC, Bingley, PJ & Williams, AJK, 2013, ‘Humoral responses to islet antigen-2 and zinc transporter 8 are attenuated in patients carrying HLA-A *24 alleles at the onset of type 1 diabetes’. Diabetes, vol 62., pp. 2067-2071 Williams, A & Long, A, 2013, ‘Following the fate of the failing ß-cell: new insights from first-phase insulin responses’. Diabetes, vol 62., pp. 3990-92 Bingley, PJ & Williams, AJK, 2013, ‘Islet autoantibody testing: an end to the trials and tribulations?’. Diabetes, vol 62., pp. 4009-11