Mathieson, Peter - University of Bristol - School of Clinical Sciences

个人简介

Peter Mathieson went to school in Cornwall, then qualified in Medicine with honours from London Hospital Medical College in 1983. After junior posts in and around the West End of London, he went to Cambridge as an MRC training fellow, studying for a PhD which was awarded by Cambridge University in 1992. After a further MRC-funded fellowship during which he worked with Professors Peter Lachmann and Doug Fearon on complement/immunology, he moved to Bristol in 1995 as the foundation Professor of Renal Medicine at Bristol University and Honorary Consultant Nephrologist, North Bristol NHS Trust. Peter was elected Fellow of the Academy of Medical Sciences in 1999. In 2007 he was elected as President of the Renal Association (the youngest ever!) and also became Head of the University Department of Clinical Science at North Bristol. He was also appointed as Director of Research & Development for the North Bristol NHS Trust. Between 2003 and 2007 he chaired the Research Grants Committee of Kidney Research UK [formerly National Kidney Research Fund]. He was a member of the Renal Association Clinical Trials committee from 1996 to 2007 and its chairman between 2000 and 2003. In 2008 Peter was appointed Dean of the Faculty of Medicine and Dentistry.

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Rigothier, CC, Saleem, MA, Bourget, C, Mathieson, PW, Combe, C & Welsh, GI, 2016, ‘Nuclear translocation of IQGAP1 protein upon exposure to puromycin aminonucleoside in cultured human podocytes: ERK pathway involvement’. Cellular Signalling, vol 28., pp. 1470-1478 Narita, I, Shimada, M, Yamabe, H, Kinjo, T, Tanno, T, Nishizaki, K, Kawai, M, Nakamura, M, Murakami, R, Nakamura, N, Tomita, H, Saleem, MA, Mathieson, PW & Okumura, K, 2015, ‘NF-κB-dependent increase in tissue factor expression is responsible for hypoxic podocyte injury’. Clinical and Experimental Nephrology. Jiang, L, Dasgupta, I, Hurcombe, JA, Colyer, HF, Mathieson, PW & Welsh, GI, 2015, ‘Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte’. Clinical Science. Rai, P, Singh, T, Lederman, R, Chawla, A, Kumar, D, Cheng, K, Valecha, G, Mathieson, PW, Saleem, MA, Malhotra, A & Singhal, PC, 2015, ‘Hyperglycemia enhances kidney cell injury in HIVAN through down-regulation of vitamin D receptors’. Cellular Signalling, vol 27., pp. 460-9 Ma, L, Shelness, GS, Snipes, JA, Murea, M, Antinozzi, PA, Cheng, D, Saleem, MA, Satchell, SC, Banas, B, Mathieson, PW, Kretzler, M, Hemal, AK, Rudel, LL, Petrovic, S, Weckerle, A, Pollak, MR, Ross, MD, Parks, JS & Freedman, BI, 2015, ‘Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines’. Journal of the American Society of Nephrology, vol 26., pp. 339-48 Leung, JCK, Chan, LYY, Saleem, MA, Mathieson, PW, Tang, SCW & Lai, KN, 2015, ‘Combined blockade of angiotensin II and prorenin receptors ameliorates podocytic apoptosis induced by IgA-activated mesangial cells’. Apoptosis, vol 20., pp. 907-20 Ramnath, R, Foster, RR, Qiu, Y, Cope, G, Butler, MJ, Salmon, AH, Mathieson, PW, Coward, RJ, Welsh, GI & Satchell, SC, 2014, ‘Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction’. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Lan, X, Jhaveri, A, Cheng, K, Wen, H, Saleem, MA, Mathieson, PW, Mikulak, J, Aviram, S, Malhotra, A, Skorecki, K & Singhal, PC, 2014, ‘APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability’. American journal of physiology. Renal physiology, vol 307., pp. F326-36 Byron, A, Randles, MJ, Humphries, JD, Mironov, A, Hamidi, H, Harris, S, Mathieson, PW, Saleem, MA, Satchell, SC, Zent, R, Humphries, MJ & Lennon, R, 2014, ‘Glomerular Cell Cross-Talk Influences Composition and Assembly of Extracellular Matrix’. Journal of the American Society of Nephrology. Hale, LJ, Hurcombe, J, Lay, AC, Santamaría, B, Valverde, AM, Saleem, MA, Mathieson, PW, Welsh, GI & Coward, RJM, 2013, ‘Insulin Directly Stimulates VEGF-A production in the Glomerular Podocyte’. American Journal of Physiology: Renal Physiology.