Madeddu, Paolo - University of Bristol - School of Clinical Sciences

个人简介

Prof. P. Madeddu, is Chair of Experimental Cardiovascular Medicine and Head of the Section of Regenerative Medicine, School of Medicine, University of Bristol, where he relocated in 2005. He was previously Associate Professor at the Medical University of Sassari and Head of Gene Therapy Department at the Inter-University Consortium of Biosystems and Biostructures, Porto Conte Technological Park, Italy. He is Associate Editor for Circulation Research, ATVB, Pharmacology &Therapeutics and Regenerative Medicine. Previously, he was Associate Editor for the British Journal of Pharmacology

研究领域

Cardiovascular regeneration

近期论文

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Wu, J, Su, W, Powner, MB, Liu, J, Copland, DA, Fruttiger, M, Madeddu, P, Dick, AD & Liu, L, 2016, ‘Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways’. Scientific Reports, vol 6. Avolio, E & Madeddu, P, 2016, ‘Discovering cardiac pericytes biology: From physiopathological mechanisms to potential therapeutic applications in ischemic heart disease’. Vascular Pharmacology. Slater, SC, Carrabba, M & Madeddu, P, 2016, ‘Vascular stem cells: Potential for clinical application’. British Medical Bulletin, vol 118., pp. 133-143 Mangialardi, G & Madeddu, P, 2016, ‘Bone Marrow-Derived Stem Cells: A Mixed Blessing in the Multifaceted World of Diabetic Complications’. Current diabetes reports, vol 16. Caporali, A, Meloni, M, Nailor, A, Mitić, T, Shantikumar, S, Riu, F, Sala-Newby, GB, Rose, L, Besnier, M, Katare, R, Voellenkle, C, Verkade, P, Martelli, F, Madeddu, P & Emanueli, C, 2015, ‘p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia’. Nature Communications, vol 6., pp. 8024 Avolio, E, Rodriguez-Arabaolaza, I, Spencer, HL, Riu, F, Mangialardi, G, Slater, SC, Rowlinson, J, Alvino, VV, Idowu, OO, Soyombo, S, Oikawa, A, Swim, MM, Kong, CHT, Cheng, H, Jia, H, Ghorbel, MT, Hancox, JC, Orchard, CH, Angelini, G, Emanueli, C, Caputo, M & Madeddu, P, 2015, ‘Expansion and Characterization of Neonatal Cardiac Pericytes Provides a Novel Cellular Option for Tissue Engineering in Congenital Heart Disease’. Journal of the American Heart Association, vol 4. Munasinghe, PE, Riu, F, Dixit, P, Edamatsu, M, Saxena, P, Hamer, NSJ, Galvin, IF, Bunton, RW, Lequeux, S, Jones, G, Lamberts, RR, Emanueli, C, Madeddu, P & Katare, R, 2015, ‘Data supporting the activation of autophagy genes in the diabetic heart’. Data in brief, vol 5., pp. 269-75 Spinetti, G, Mangialardi, G, Specchia, C & Madeddu, P, 2015, ‘Enhancing Stem Cell Mobility: New Hope for Treatment of Cardiovascular Complications in Patients With Diabetes?’. Diabetes, vol 64., pp. 2704-7 Gubernator, M, Slater, SC, Spencer, HL, Spiteri, I, Sottoriva, A, Riu, F, Rowlinson, J, Avolio, E, Katare, R, Mangialardi, G, Oikawa, A, Reni, C, Campagnolo, P, Spinetti, G, Touloumis, A, Tavaré, S, Prandi, F, Pesce, M, Hofner, M, Klemens, V, Emanueli, C, Angelini, G & Madeddu, P, 2015, ‘Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia’. Arteriosclerosis, Thrombosis and Vascular Biology, vol 35., pp. 675-88 Meloni, M, Cesselli, D, Caporali, A, Mangialardi, G, Avolio, E, Reni, C, Fortunato, O, Martini, S, Madeddu, P, Valgimigli, M, Nikolaev, E, Kaczmarek, L, Angelini, GD, Beltrami, AP & Emanueli, C, 2015, ‘Cardiac Nerve Growth Factor Overexpression Induces Bone Marrow-derived Progenitor Cells Mobilization and Homing to the Infarcted Heart’. Molecular Therapy.