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研究领域

Ophthalmology, Inflammation, Angiogenesis, Microglia, Macrophage

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Wu, J, Su, W, Powner, MB, Liu, J, Copland, DA, Fruttiger, M, Madeddu, P, Dick, AD & Liu, L, 2016, ‘Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways’. Scientific Reports, vol 6. Liu, J, Copland, DA, Theodoropoulou, S, Chiu, HAA, Barba, MD, Mak, KW, Mack, M, Nicholson, LB & Dick, AD, 2016, ‘Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis’. Scientific Reports, vol 6. Theodoropoulou, S, Copland, DA, Liu, J & Dick, AD, 2015, ‘Role of interleukin 33/ST2 axis in the immune-mediated pathogenesis of age-related macular degeneration’. The Lancet, vol 385., pp. S97 Xu, Y, Balasubramaniam, B, Copland, DA, Liu, J, Armitage, MJ & Dick, AD, 2015, ‘Activated adult microglia influence retinal progenitor cell proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model’. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Wu, W-K, Georgiadis, A, Copland, DA, Liyanage, S, Luhmann, UFO, Robbie, SJ, Liu, J, Wu, J, Bainbridge, JW, Bates, DO, Ali, RR, Nicholson, LB & Dick, AD, 2015, ‘IL-4 Regulates Specific Arg-1(+) Macrophage sFlt-1-Mediated Inhibition of Angiogenesis’. American Journal of Pathology. Horie, S, Robbie, SJ, Liu, J, Wu, W-K, Ali, RR, Bainbridge, JW, Nicholson, LB, Mochizuki, M, Dick, AD & Copland, DA, 2013, ‘CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization’. Scientific Reports, vol 3., pp. 3072 Liu, J, Copland, DA, Horie, S, Wu, W-K, Chen, M, Xu, Y, Morgan, BP, Mack, M, Xu, H, Nicholson, LB & Dick, AD, 2013, ‘Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice’. PloS one, vol 8., pp. e72935 Copland, DA, Liu, J, Schewitz-Bowers, LP, Brinkmann, V, Anderson, K, Nicholson, LB & Dick, AD, 2012, ‘Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier’. The American journal of pathology, vol 180., pp. 672 - 681 Chen, M, Copland, D, Zhao, J, Liu, J, Forrester, J, Dick, A & Xu, H, 2012, ‘Persistent inflammation subverts thrombospondin-1-induced regulation of retinal angiogenesis and is driven by CCR2 ligation’. The American journal of pathology, vol 180., pp. 235-45 Westgarth, C, Liu, J, Heron, J, Ness, A, Bundred, P, Gaskell, R, German, A, McCune, S & Dawson, S, 2012, ‘Dog Ownership during Pregnancy, Maternal Activity, and Obesity: A Cross-Sectional Study’. Plos One, vol 7.

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