Kerrigan, Talitha - University of Bristol - School of Clinical Sciences

研究领域

The dynamic role of astrocyte secreted APOE4 in Alzheimer's disease; investigation using human induced pluripotent stem cells

近期论文

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Tamagnini, F, Novelia, J, Kerrigan, TL, Brown, JT, Tsaneva-Atanasova, K & Randall, AD, 2015, ‘Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice’. Frontiers in Cellular Neuroscience, vol 9., pp. 372 Kerrigan, TL, Brown, JT & Randall, AD, 2014, ‘Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse’. Neuropharmacology, vol 79., pp. 515-24 Kerrigan, TL & Randall, AD, 2013, ‘A new player in the "synaptopathy" of Alzheimer's disease - arc/arg 3.1’. Frontiers in neurology, vol 4., pp. 9 Whitehead, G, Jo, J, Hogg, EL, Piers, T, Kim, D-H, Seaton, G, Seok, H, Bru-Mercier, G, Son, GH, Regan, PL, Hildebrandt, L, Waite, E, Kim, B-C, Kerrigan, TL, Kim, K, Whitcomb, DJ, Collingridge, GL, Lightman, SL & Cho, K, 2013, ‘Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus’. Brain, vol 136., pp. 3753-3765 Crompton, LA, Byrne, ML, Taylor, H, Kerrigan, TL, Bru-Mercier, G, Badger, JL, Barbuti, PA, Jo, J, Tyler, SJ, Allen-Birt, SJ, Kunath, T, Cho, K & Caldwell, MA, 2013, ‘Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling’. Stem Cell Research, vol 11., pp. 1206-1221 Watt, NT, Taylor, DR, Kerrigan, TL, Griffiths, HH, Rushworth, JV, Whitehouse, IJ & Hooper, NM, 2012, ‘Prion protein facilitates uptake of zinc into neuronal cells’. Nature Communications, vol 3., pp. 1134 Kerrigan, TL, J, WD, Regan, PL & Cho, K, 2012, ‘The role of neuronal calcium sensors in balancing synaptic plasticity and synaptic dysfunction’. Frontiers in Molecular Neuroscience, vol 5., pp. 57 - 57 Jo, J, Whitcomb, DJ, Olsen, KM, Kerrigan, TL, Lo, S-C, Bru-Mercier, G, Dickinson, B, Scullion, S, Sheng, M, Collingridge, G & Cho, K, 2011, ‘Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β’. Nature Neuroscience, vol 14., pp. 545 - 547 Dallas, ML, Boyle, JP, Milligan, CJ, Sayer, R, Kerrigan, TL, McKinstry, C, Lu, P, Mankouri, J, Harris, M, Scragg, JL, Pearson, HA & Peers, C, 2011, ‘Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1’. The FASEB Journal, vol 25., pp. 1519-30 Kerrigan, TL, Atkinson, L, Peers, C & Pearson, HA, 2008, ‘Modulation of 'A'-type K+ current by rodent and human forms of amyloid beta protein’. Neuroreport, vol 19., pp. 839-43