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Donegan, R.K., Hill, S.H., Freeman, D.M., Nguyen, E., Orwig, S.D., Turnage, K.C., Lieberman, R.L. Structural basis for misfolding in myocilin-associated glaucoma. Hum. Mol. Genet. 2014. (DOI: 10.1093/hmg/ddu730)
Stothert, A. R., Suntharalingam, A., Huard, D. J., Fontaine, S. N., Crowley, V. M., Mishra, S., Blagg B. S., Lieberman, R. L., Dickey, C.A. Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma. Hum. Mol. Genet. 2014, 23(24), pp. 6470-80. (DOI: 10.1093/hmg/ddu367)
Yu, Y., Mena-Barragan, T., Higaki. K., Johnson, J. L., Drury, J. E., Lieberman, R. L., Nakasone, N., Ninomiya, H., Tsukimura, T., Sakuraba, H., Suzuki, Y., Nanba, E., Mellet, C. O., Garcia Fernandez, J. M., Ohno, K. Molecular basis of 1-deoxygalactonojirimycin arylthiourea binding to human alpha-galactosidase a: pharmacological chaperoning efficacy on Fabry disease mutants. ACS Chem. Biol. 2014, 9(7), pp. 1460-9. (DOI: 10.1021/cb500143h)
Kalyoncu, S., Hyun, J., Pai, J. C., Johnson, J.L., Entzminger, K., Jain, A., Heaner, D. P., Morales, I. A., Truskett, T. M., Maynard, J. A., Lieberman, R. L. Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments. Proteins: Structure, Function, and Bioinformatics. 2014, 82(9), pp. 1884-95. (DOI: 10.1002/prot.24542)
Bethel, C. M., Lieberman, R. L. Protein structure and function: A multimedia-based guided-inquiry education module for the high school science classroom, J. Chem. Educ. 2014, 91(1), pp. 52-55.
Hill, S. H., Donegan, R. K., Lieberman, R. L. The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence. 2013, 426(4), pp. 921-35. (DOI: 10.1016/j.jmb.2013.12.002)
Orwig, S. D., Chi, P., Du, Y., Hill, S. E., Cavitt, M.A., Suntharalingam, A. Turnage, K. C., Dickey, C.A., France, S., Fu, H., Lieberman, R. L. Ligands for glaucoma-associated myocilin discovered by a generic binding assay. ACS Chemical Biology. 2013, 9(2), pp. 517-25. (DOI: 10.1021/cb40077766)
Lieberman R. L., Peek, M. E., Watkins, J. D. Determination of soluble and membrane protein structures by X-ray crystallography. Methods Mol. Biol. 2013, 955, pp. 475-93. (DOI: 10.1007/978-1-62703-176-9_25)
Donegan, R. K., Lieberman, R. L. New direction for glaucoma therapeutics: focus on the olfactomedin domain of myocilin. Future Medicinal Chemistry. 2012, 4(17), pp. 2131-4.(DOI: 10.4155/FMC.12.132)
Donegan, R. K., Hill, S. E., Turnage, K. C., Orwig, S. D., Lieberman, R. L. The glaucoma-associated olfactomedin domain of myocilin is a novel calcium-binding protein. J. Biol. Chem. 2012, 287(52), pp. 43370-7. (DOI:10.1074/jbc.M112.408906)
Suntharalingam, A. Abisambra, J. F., O'Leary III, J. C. Koren, J., Zhang,B., Joe, M. K., Blair, L. J., Hill, S. E.Jinwal,U. K.,Cockman,M. Duerfeldt, S. F., Tomarev, S.I., Blagg, B. S. J., LIeberman, R. L., Dickey, C.A Grp94 triage of mutant myocilin through ERAD subverts a more efficient a more efficient clearance mechanism. J. Biol. Chem. 2012, 287(48), pp. 40661-9. (DOI:10.1074/jbc.M112.384800)
Orwig, S. D., Perry, C. W., Kim, L. Y, Turnage, K. C., Zhang, R., Vollrath, D., Schmidt-Krey, I., Lieberman, R. L., Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin. J. Mol. Biol. 2011, 421(2-3), pp. 242-55. (DOI: 10.1016/j.jmb.2011.12.016)
Lieberman, R. L. A guided tour of the structural biology of Gaucher disease: acid-beta-glucosidase and saposin c. Enzyme Research 2011, 2011. (DOI:10.4061/2011/973231)
Orwig, S. D., Tan, Y. L., Grimster, N. P., Yu, Z., Powers, E., Kelly, J. W., Lieberman, R. L. Binding of 3,4,5,6-tetrahydroxyazepanes to the acid b glucosidase active site: Implications for pharmacological chaperone design for Gaucher disease. Biochemistry. 2011, 50(49), pp. 10647-57. (DOI:10.1021/bi201619z)
Lieberman, R. L. Sneak peak at galactocerebrosidase, Krabbe disease's lysosomal hydrolase. Proc. Natl. Acad. Sci USA. 2011, 108(37), pp. 15017-8. (DOI: 10.1073/pnas.1112653108)
Lieberman, R. L., Culver, J. A., Entzminger, K. C., Pai, J. C.; Maynard, J. A. Crystallization chaperone strategies for membrane proteins. Invited review, Methods. 2011, 55(4), pp. 293-302. (DOI:10.1016/j.ymeth.1011.08.004)
Burns, J. N., Turnage, K. C. Walker, C. A., Lieberman, R. L. The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder. Biochemistry. 2011, 50(26), pp. 5824-5833. (DOI:10.1021/bi200231x)
Orwig, S. D. and Lieberman, R. L. Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix implicated in the inherited form of glaucoma. PLoS One. 2011, 6(1): e16347. (DOI:10.1371/journal.pone.0016347)
Pai, J. C.; Culver, J. A.; Drury, J. E.; Lieberman, R. L., Maynard, J. A. Conversion of scFv peptide-binding specificity for crystal chaperone development. Protein Engineering Design and Selection. 2010, 24(5), pp. 419-428. (DOI: 10.1093/protein/gzq120)
Burns, J. N.; Orwig, S. D.; Harris, J. L.; Watkins, J. D.; Vollrath, D.; Lieberman, R. L. Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones. ACS Chemical Biology. 2010, 5(5), pp. 477-487. (DOI: 10.1021/cb900282e)