个人简介
讲授课程《病毒学》、《病毒学实验》等
华中农业大学教授、博士生导师。2004年于华中农业大学获得农学博士学位。目前主持国家自然科学基金面上项目2项、校自主创新基金1项,作为研究骨干参与十三五国家重点研发计划1项。以(共同)通讯或第一作者在《J Virol》、《Antiviral Res》、《Transbound Emerg Dis》和《Veterinary Microbiology》等刊物上发表研究论文20余篇;获得湖北省科技进步一等奖2项,授权国家发明专利7项。
教育经历
1995.09 - 1999.06,河南农业大学,兽医卫生检验专业毕业,农学学士
1999.09 - 2004.06, 华中农业大学,预防兽医学专业毕业,农学博士
工作经历
2008.12-至今,华中农业大学 教授、博士生导师
2004.06-2008.12,华中农业大学 讲师
科研项目
1. 塞内卡病毒(SVA)3C蛋白抑制I型干扰素产生的分子机制(国家自然基金面上项目,2018.01-2021.12).
2.病原诱导天然免疫应答及其调控机制(十三五重点研发项目. 2016.07-2020.12)
3. 酮戊二酸脱氢酶(OGDH)在TRIM15调控IFN-β信号通路中的功能及机制研究(国家自然基金面上项目,2016.01-2019.12).
4. 微生态制剂对高架网床生态养猪促进作用与应用(校自主科技创新基金项目--标志性成果培育, 2016.01-2018.12)
主要奖励
湖北省科技进步一等奖2项。
近期论文
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1. Qian S, Fan W, Liu T, Wu M, Zhang H, Cui X, Zhou Y, Hu J, Wei S, Chen H, Li X*, Qian P*. Seneca Valley Virus suppresses host type I interferon production by targeting adaptor proteins MAVS, TRIF, and TANK for cleavage. J Virol. 2017 May 31. pii: JVI.00823-17.
2. Zhang H, Wen W, Hao G, Hu Y, Chen H, Qian P, Li X*. Phylogenetic and genomic characterization of a novel atypical porcine pestivirus in China. Transbound Emerg Dis. 2017 Jul 14.
3. Wenchun Fan, Mengge Wu, Suhonh Qian, Yun Zhou, Huanchun Chen, Xiangmin Li*, Ping Qian*. TRIM52 inhibits Japanese Encephalitis virus replication by degrading the viral NS2A. Sci Rep. 2016 Sep 26; 6: 33698.
4. Qian S, Fan W, Qian P, Chen H, Li X*. Isolation and full-genome sequencing of Seneca Valley virus in piglets from China, 2016. Virol J. 2016 Oct 19; 13(1): 173.
5. Huawei Zhang, Haixue Zheng, Ping Qian, Jinfang Xu, Xi Yang, Rui Zhou, Huanchun Chen, Xiangmin Li*. Induction of systemic IFITM3 expression does not effectively control foot-and-mouth disease viral infection in transgenic pigs. Veterinary Microbiology. 15 August 2016, Volume 191, Pages 20–26.
6. Fan W, Qian S, Qian P, Li X*. Antiviral activity of luteolin against Japanese encephalitis virus. Virus Res. 2016 Jul 15; 220: 112-6.
7. Fan W, Zhang D, Qian P, Qian S, Wu M, Chen H, Li X*. Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism. Antiviral Res. 2016 Mar; 127: 32-40.
8. Qian P, Zhi X, Wang B, Zhang H, Chen H, Li X*. Construction and immune efficacy of recombinant pseudorabies virus expressing PrM-E proteins of Japanese encephalitis virus genotype І. Virol J. 2015 Dec 10; 12: 214.
9. Zhang H, Qian P, Peng B, Shi L, Chen H, Li X*. A novel subunit vaccine co-expressing GM-CSF and PCV2b Cap protein enhances protective immunity against porcine circovirus type 2 in piglets. Vaccine. 2015 May 15; 33(21): 2449-56.
10. Qian S, Fan W, Qian P, Zhang D, Wei Y, Chen H, Li X*. Apigenin restricts FMDV infection and inhibits viral IRES driven translational activity. Viruses. 2015 Mar 31; 7(4): 1613-26.
11. Zhang H, Qian P, Liu L, Qian S, Chen H, Li X*. Virus-like particles of chimeric recombinant porcine circovirus type 2 as antigen vehicle carrying foreign epitopes. Viruses. 2014 Dec 5; 6(12): 4839-55.
12. Li X, Zhu Q, Cao Q, Chen H, Qian P*. Japanese encephalitis virus upregulates the expression of SOCS3 in mouse brain and Raw264.7 Cells. Viruses. 2014 Nov 10; 6(11): 4280-93.
13. Xu J, Qian P, Wu Q, Liu S, Fan W, Zhang K, Wang R, Zhang H, Chen H, Li X*. Swine interferon-induced transmembrane protein, sIFITM3, inhibits foot-and-mouth disease virus infection in vitro and in vivo. Antiviral Res. 2014 Sep;109: 22-9.
14. Cao QS, Li XM, Zhu QY, Wang DD, Chen HC, Qian P*. Isolation and molecular characterization of genotype 1 Japanese encephalitis virus, SX09S-01, from pigs in China. Virol J. 2011 Oct 14; 8: 472.