张华 - 华中农业大学 - 生命科学技术学院

个人简介

教育经历 1994-1998 湖南农业大学食品科学技术学院食品工程专业工学学士学位 2000-2003 西南农业大学资源与环境学院微生物学专业理学硕士学位 2003-2008 中国科学院沈阳应用生态研究所微生物学专业理学博士学位科研与学术工作经历 2008-至今华中农业大学生命科学技术学院讲师，副教授获得奖励 2012-2014年获华中农业大学教学质量三等奖主讲课程微生物学基础、普通微生物学实验研究生招生专业微生物致病信号网络与新药靶标

研究领域

从蛋白质-蛋白质相互作用及蛋白质-核酸相互作用出发，研究基因调控结核分枝杆菌生长及耐药相关的课题

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Liu Y, Wang H, Cui T, Zhou X, Jia Y, Zhang H*, He ZG*. (2016) NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs.Mol Microbiol. 101, 167-181. 2. Zhang H, Zhang Z, Yang J, He ZG. (2014) Functional characterization of DnaB helicase and its modulation by single-stranded DNA-binding protein in Mycobacterium tuberculosis. FEBS J. 281, 1256-1266. 3. Zhang H, Gao L, Zhang J, Li W, Yang M, Zhang H, Gao C, He ZG. (2014) A novel marRAB operon contributes to the rifampicin resistance in Mycobacterium smegmatis.PloS One. 9, e106016. 4. Du Y, Zhang H, He Y, Huang F, He ZG. (2012) Mycobacterium smegmatis Lsr2 physically and functionally interacts with a new flavoprotein involved in bacterial resistance to oxidative stress. J Biochem. 152, 479-486. 5. Zhang H#, Tian Y#, Liu Z, Huang F, Hu L, He ZG. (2011) Characterization of amino acid residues essential for tetramer formation and DNA-binding activity of ssDNA-binding protein of Mycobacterium tuberculosis. Biochemistry (Mosc). 76, 658-665. 6. Sun L, Zhang L, Zhang H, He ZG. (2011) Characterization of a bifunctional β-Lactamase/Ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv. Biochemistry (Mosc). 76, 350-358. 7. Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y, Huang F, Zeng J, Huang C, Yang Q, Tian Y, Zhao C, Chen H, Zhang H, He ZG. (2010) Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv. J. Proteome. Res. 9, 6665–6677. 8. Li Y, Zeng J, Zhang H, He ZG. (2010) The characterization of conserved binding motifs and potential target genes for M. tuberculosis MtrAB reveals a link between the two-component system and the drug resistance of M. smegmatis. BMC Microbiol.10, 242. 9. Yang M, Gao C, Wang Y, Zhang H, He ZG. (2010) Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules. PLoS One, e10672. 10. Zhang H, Bi L, Li C, Sun Z, Deng J, Zhang XE. (2009) Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China. J. Int. Med. Res. 37, 1430-1435. 11. Zhang H, Deng J, Bi L, Zhou Y, Zhang Z, Zhang C, Zhang Y. Zhang XE. (2008) Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase. FEBS J. 275, 753-762.