汪骞 - 中国科学技术大学

个人简介

2020年4月入职中国科学技术大学物理系，中科院百人计划，特任研究员/博导 2003-2007/6 中国科学技术大学近代物理系，学士 2007-2012/5 美国休斯敦大学物理系，博士 2012-2015/2 美国德州大学医学部，结构生物和分子生物物理学中心，博士后 2015-2020/1 美国莱斯大学理论生物物理学中心，博士后

研究领域

通过分子动力学模拟和生物系统建模，理解生物大分子的功能和动力学特性

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Q. Wang#,*, Jie Yang,#, Zhicheng Zhong, Jeffrey A. Vanegas, Xue Gao*, Anatoly B. Kolomeisky*, "A General Theoretical Framework to Design Base Editors with Reduced Bystander Effects", Nature Communications, 12, 6529 (2021) Q. Wang#,*, Lin Wang#, Yumin Zhang#, XiangLei Zhang, Leike Zhang, Weijuan Shang* and Fang Bai*, "Probing the Allosteric Inhibition Mechanism of a Spike Protein Using Molecular Dynamics Simulations and Active Compound Identifications", Journal of Medicinal Chemistry (https://doi.org/10.1021/acs.jmedchem.1c00320) (2021) Q. Wang, M. Chen, N. P. Schafer, C. Bueno, P. G. Wolynes, M. N. Waxham and M. S. Cheung, “Assemblies of Calcium/Calmodulin Dependent Kinase II with Actin and Their Dynamic Regulation by Calmodulin in Dendritic Spines”, PNAS, 116 (38), 18937-18942 (2019) Q. Wang, B. Jana, M. R Diehl, M. S. Cheung, A. B. Kolomeisky and J. N. Onuchic, “Molecular Mechanisms of the Interhead Coordination by Interhead Tension in Cytoplasmic Dyneins”, PNAS, 115 (40), 10052-10057 (2018) Q. Wang, M. R. Diehl, B. Jana, M. S. Cheung, A. B. Kolomeisky and J. N. Onuchic, “Molecular Origin of the Weak Susceptibility of Kinesin Velocity to Loads and its Relation to the Collective Behavior of Kinesins”, PNAS, 114, E8611–E8617 (2017) Q. Wang, R. N. Irobalieva, W. Chiu, M. F. Schmid, J. M. Fogg, L. Zechiedrich, and B. Montgomery Pettitt, “Influence of DNA sequence on the structure of minicircles under torsional stress”, Nucleic Acids Research, 45 (13), 7633-7642 (2017) Q. Wang#, P. Zhang#, S. Tripathi, L. Hoffman, L. Yin, M. N. Waxham, M. S. Cheung, "Protein recognition and selection through conformational and mutually induced fit", PNAS, 110, 20545-20550 (2013) Q. Wang and A. B. Kolomeisky, “Theoretical Analysis of Run Length Distributions for coupled Motor Proteins”, Journal of Physical Chemistry B, 123 (27), 5805-5813 (2019) Q. Wang and B. Montgomery Pettitt, “Sequence Affects the Cyclization of DNA Minicircles”, Journal of Physical Chemistry Letter, 7, pp 1042–1046 (2016) Q. Wang and B. Montgomery Pettitt, “Modeling DNA Thermodynamics under Torsional Stress”, Biophysical Journal, 106, 1182-1193 (2014) Q. Wang and M. S. Cheung, “A Physics-based Approach of Coarse-graining the Cytoplasm of E. coli (CGCYTO)”, Biophysical Journal, 102, 2353-2361 (2012) Q. Wang, Kao-Chen Liang, A. Czader, M. N. Waxham, M. S. Cheung, "The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics", PLoS Computational Biology, 7: e1002114 (2011)