Willis, Chris - University of Bristol

研究领域

Natural Products: Synthesis and Biosynthesis

近期论文

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Byrne, MJ, Lees, NR, Han, LC, Van Der Kamp, MW, Mulholland, AJ, Stach, JEM, Willis, CL & Race, PR, 2016, ‘The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail’. Journal of the American Chemical Society, vol 138., pp. 6095-6098 Bailey, AM, Alberti, F, Kilaru, S, Collins, CM, De Mattos-Shipley, K, Hartley, AJ, Hayes, P, Griffin, A, Lazarus, CM, Cox, RJ, Willis, CL, O'Dwyer, K, Spence, DW & Foster, GD, 2016, ‘Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production’. Scientific Reports, vol 6. Williams, K, Szwalbe, AJ, Mulholland, NP, Vincent, JL, Bailey, A, Willis, CL, Simpson, TJ & Cox, RJ, 2016, ‘Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis’. Angewandte Chemie (International ed. in English). Szwalbe, AJ, Williams, K, O'Flynn, DE, Bailey, AM, Mulholland, NP, Vincent, JL, Willis, CL, Cox, RJ & Simpson, TJ, 2015, ‘Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 – an insight into the biosynthesis of maleidrides’. Chemical Communications, vol 51., pp. 17088-17091 Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T, Willis, C & Crump, M, 2015, ‘Recognition of extended linear and cyclised polyketide mimics by a Type II acyl carrier protein’. Chemical Science, vol 7., pp. 1779-1785 Beattie, RJ, Hornsby, T, Craig, G, Galan, MC & Willis, CL, 2015, ‘Stereoselective synthesis of protected l- and d-dideoxysugars and analogues via Prins cyclisations’. Chemical Science, vol 7., pp. 2743-2747 Shoemark, DK, Williams, C, Fahey, MS, Watson, JJ, Tyler, SJ, Scoltock, SJ, Ellis, R, Wickendon, E, Burton, AJ, Hemmings, JLL, Bailey, CD, Dawbarn, D, Jane, DE, Willis, CL, Sessions, RB, Allen, SJ & Crump, MP, 2015, ‘Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery’. Journal of Medicinal Chemistry, vol 58., pp. 767-777 Ackrill, TD, Sparkes, HA & Willis, CL, 2015, ‘Synthesis of Diarylheptanoid Scaffolds Inspired by Calyxins I and J’. Organic Letters, vol 17., pp. 3884-3887 Hesse, MJ, Essafi, S, Watson, CG, Harvey, JN, Hirst, D, Willis, CL & Aggarwal, VK, 2014, ‘Highly Selective Allylborations of Aldehydes Using alpha,alpha-Disubstituted Allylic Pinacol Boronic Esters’. Angewandte Chemie International Edition, vol 53., pp. 6145-6149 Gao, S-S, Hothersall, J, Wu, J, Murphy, AC, Song, Z, Stephens, ER, Thomas, CM, Crump, MP, Cox, RJ, Simpson, TJ & Willis, CL, 2014, ‘Biosynthesis of Mupirocin by Pseudomonas fluorescens NCIMB 10586 Involves Parallel Pathways’. Journal of the American Chemical Society, vol 136., pp. 5501-5507 Cons, BD, Bunt, AJ, Bailey, CD & Willis, CL, 2013, ‘Total Synthesis of (-)-Blepharocalyxin D and Analogues’. Organic Letters, vol 15., pp. 2046-2049 Murphy, AC, Gao, S-S, Han, L-C, Carobene, S, Fukuda, D, Song, Z, Hothersall, J, Cox, RJ, Crosby, J, Crump, MP, Thomas, CM, Willis, CL & Simpson, TJ, 2013, ‘Biosynthesis of thiomarinol A and related metabolites of Pseudoalteromonas sp SANK 73390’. Chemical Science, vol 5., pp. 397-402