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Immune mechanisms of autoimmune disorders of the eye

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Wu, J, Su, W, Powner, MB, Liu, J, Copland, DA, Fruttiger, M, Madeddu, P, Dick, AD & Liu, L, 2016, ‘Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways’. Scientific Reports, vol 6. Jaffe, GJ, Dick, AD, Brézin, AP, Nguyen, QD, Thorne, JE, Kestelyn, P, Barisani-Asenbauer, T, Franco, P, Heiligenhaus, A, Scales, D, Chu, DS, Camez, A, Kwatra, NV, Song, AP, Kron, M, Tari, S & Suhler, EB, 2016, ‘Adalimumab in Patients with Active Noninfectious Uveitis’. New England Journal of Medicine, vol 375., pp. 932-943 Nguyen, QD, Merrill, PT, Jaffe, GJ, Dick, AD, Kurup, SK, Sheppard, J, Schlaen, A, Pavesio, C, Cimino, L, Van Calster, J, Camez, AA, Kwatra, NV, Song, AP, Kron, M, Tari, S & Brézin, AP, 2016, ‘Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial’. Lancet, vol 388., pp. 1183-1192 Dick, AD, 2016, ‘Doyne lecture 2016: intraocular health and the many faces of inflammation’. Eye. Márquez, A, Cordero-Coma, M, Martín-Villa, JM, Gorroño-Echebarría, MB, Blanco, R, Valle, DD, Rio, MJD, Blanco, A, Olea, JL, Cordero, Y, Capella, MJ, Díaz-Llopis, M, Ortego-Centeno, N, Ruiz-Arruza, I, Llorenç, V, Adán, A, Fonollosa, A, Berge, JT, Atan, D, Dick, AD, De Boer, JH, Kuiper, J, Rothova, A & Martín, J, 2016, ‘New insights into the genetic component of non-infectious uveitis through an Immunochip strategy’. Journal of Medical Genetics. Chu, CJ, Gardner, PJ, Copland, DA, Liyanage, SE, Gonzalez-Cordero, A, Holthaus, S-M, Luhmann, UFO, Smith, AJ, Ali, RR & Dick, AD, 2016, ‘Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model’. Disease Models & Mechanisms, vol 9., pp. 473-81 Nicholls, SM, Pong-Wong, R, Mitchard, LK, Harley, R, Archibald, AL, Dick, AD & Bailey, M, 2016, ‘Genome-Wide Analysis in Swine Associates Corneal Graft Rejection with Donor-Recipient Mismatches in Three Novel Histocompatibility Regions and One Locus Homologous to the Mouse H-3 Locus’. PLoS ONE, vol 11. Molins, B, Fuentes-Prior, P, Adán, A, Antón, R, Arostegui, JI, Yagüe, J & Dick, AD, 2016, ‘Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants’. Scientific Reports, vol 6. Liu, J, Copland, DA, Theodoropoulou, S, Chiu, HAA, Barba, MD, Mak, KW, Mack, M, Nicholson, LB & Dick, AD, 2016, ‘Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis’. Scientific Reports, vol 6. Thorne, JE, Skup, M, Tundia, N, Macaulay, D, Revol, C, Chao, J, Joshi, A & Dick, AD, 2016, ‘Direct and indirect resource use, healthcare costs and work force absence in patients with non-infectious intermediate, posterior or panuveitis’. Acta Ophthalmologica.

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