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研究领域

Our research is focused on the biology of childhood leukaemia and on ex vivo expansion of haemopoietic stem cells for therapeutic use

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Chang, C-H., Hale, S.J., Cox, C.V., Blair, A., Kronsteiner, B., Grabowska, R., Youyi Zhang, Y., Cook, D., Khoo, C.P., Schrader, J.B., Kabuga, S.B., Martin-Rendon, E. and Watt, S.M. (2016) JAM-A is highly expressed onhuman hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxr4. Stem Cells prepub online: DOI: 10.1002/stem.2340 Williams, M.T.S., Yousafzai, Y., Cox, C., Blair, A., Carmody, R., Sai, S., Chapman, K.E., McAndrew, R., Thomas, A., Spence, A., Gibson, B., Graham, G.J. and Halsey, C. (2014) Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia. Blood 123, 3116-3127. Diamanti, P., Cox, C.V., Moppett, J.P. and Blair, A. (2013) Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia. Blood 121(8),1384-1393. Diamanti P., Cox C.V. and Blair, A. (2012) Comparison of childhood leukemia initiating cell populations in NOD/SCID and NSG mice. Leukemia 26(2),376-380. Diamanti, P. and Blair, A. (2009) Stem cells in childhood acute lymphoblastic leukemia: identifying the most relevant targets for therapy. Blood 113, 4477-4478. Cox, C.V., Diamanti, P., Evely, R.S., Kearns, P.R. and Blair, A. (2009) Expression of CD133 on leukemia initiating cells in childhood ALL. Blood 113, 3287-3296. Yan, M., Himoudi, N., Pule, M., Sebire, N., Poon, E., Blair, A., Williams, O. and Anderson, J. (2008) Development of cellular immune responses against PAX5, a novel target for cancer immunotherapy. Cancer Res. 68, 8058-8065. Eichler, H., Nguyen, X.D., Roelen, D., Celluzzi, C.M., McKenna, D., Pamphilon, D., Blair, A., Read, E.J., Takahashi, T.A., Szczepiorkowski, Z.M. (2008) Biomedical Excellence for Safer Transfusion Collaborative. Multicenter study on in vitro characterization of dendritic cells. Cytotherapy 10, 21-29. Cox, C.V., Martin, H.M., Kearns, P.R., Virgo, P., Evely, R.S. and Blair, A. (2007) Characterisation of a progenitor cell population in childhood T cell Acute Lymphoblastic Leukemia. Blood 109, 674-682.

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