Mellor, Harry - University of Bristol - School of Biochemistry

个人简介

BSc (Hons) Biochemistry, University of Edinburgh (1988) PhD Biochemistry, University of Bristol, School of Biochemistry, (1992) Juvenile Diabetes Foundation International Personal Fellowship, Penn State University (1993-1995) Postdoctoral Fellow, Cancer Research UK, London Research Institute (1995-1998) Wellcome Trust Career Development Fellowship, University of Bristol (1998-2003) Welcome Trust University Award, University of Bristol (2003-2008) Reader in Biochemistry, University of Bristol (2005-2010) Professor of Biochemistry, University of Bristol (2010-present)

研究领域

Endothelial cell dynamics in angiogenesis

近期论文

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Richards, MD, Hetheridge, CL & Mellor, H, 2015, ‘The Formin FMNL3 Controls Early Apical Specification in Endothelial Cells by Regulating the Polarized Trafficking of Podocalyxin’. Current Biology, vol 27., pp. 2325-2331 Hetheridge, C, Scott, AN, Swain, RK, Copeland, JW, Higgs, HN, Bicknell, R & Mellor, H, 2012, ‘The formin FMNL3 is a cytoskeletal regulator of angiogenesis’. Journal of Cell Science, vol 125., pp. 1420-8 Gampel, A, Moss, L, Jones, MC, Brunton, V, Norman, JC & Mellor, H, 2006, ‘VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment’. Blood, vol 108., pp. 2624 - 2631 Pellegrin, S & Mellor, H, 2005, ‘The Rho family GTPase Rif induces filopodia through mDia2’. Current Biology, vol 15., pp. 129 - 133 Sandilands, E, Cans, C, Fincham, V, Brunton, V, Mellor, H, Prendergast, G, Norman, J, Superti-Furga, G & Frame, M, 2004, ‘RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane’. Developmental Cell, vol 7., pp. 855 - 869 Carlton, J, Bunjy, M, Peter, B, Oorschot, V, Rutherford, A, Mellor, H, Klumperman, J, McMahon, H & Cullen, P, 2004, ‘Sorting Nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides’. Current Biology, vol 14 (20)., pp. 1791 - 1800 Ellis, S & Mellor, H, 2000, ‘The novel Rho-family GTPase Rif regulates coordinated actin-based membrane rearrangements’. Current Biology, vol 10., pp. 1387 - 1390 Heesom, K, Gampel, A, Mellor, H & Denton, R, 2001, ‘Cell cycle-dependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)’. Current Biology, vol 11., pp. 1374-1379 Gampel, A, Parker, P & Mellor, H, 1999, ‘Regulation of epidermal growth factor receptor traffic by the Small GTPase RhoB’. Current Biology, vol 9., pp. 955 - 958 Ng, T, Squire, A, Hansra, G, Bornancin, F, Prevostel, C, Hanby, A, Harris, W, Barnes, D, Schmidt, S, Mellor, H, Bastiaens, P & Parker, P, 1999, ‘Imaging protein kinase C-alpha activation in cells’. Science, vol 283., pp. 2085 - 2089