Lane, Jon - University of Bristol - School of Biochemistry

研究领域

Molecular regulation of autophagy

近期论文

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MacVicar, T, Mannack, L, Lees, RM & Lane, J, 2015, ‘Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells’. International Journal of Molecular Sciences., pp. 13356-13380 Liang, J-R, Lane, J, Mayor, U, Clague, M & Urbe, S, 2015, ‘USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death’. EMBO Reports. MacVicar, T, Mannack, L, Lees, R & Lane, J, 2015, ‘argeted siRNA screens identify ER-to-mitochondrial calcium exchange in autophagy and mitophagy responses in RPE1 cells’. International journal of molecular sciences., pp. 13356-13380 Morgan, RG, Molnar, E, Jones, RF, Collard, TJ, Lane, JD, Greenhough, A, Paraskeva, C & Williams, AC, 2014, ‘Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells’. British Journal of Cancer, vol 112., pp. 714-719 Mannack, LVJ & Lane, JD, 2014, ‘The autophagosome: current understanding of formation and maturation’. Research and Reports in Biochemistry, vol 2015., pp. 39-58 Curtis, DJ, Sood, A, Phillips, TEJ, Leinster, VHL, Nishiguchi, A, Coyle, C, Lacharme-Lora, L, Beaumont, O, Kemp, H, Goodall, R, Cornes, L, Giugliano, M, Barone, RA, Matsusaki, M, Akashi, M, Tanaka, HY, Kano, M, McGarvey, J, Halemani, ND, Simon, K, Keehan, R, Ind, W, Masters, T, Grant, S, Athwal, S, Collett, G, Tannetta, D, Sargent, IL, Scull-Brown, E, Liu, X, Aquilina, K, Cohen, N, Lane, JD, Thoresen, M, Hanley, J, Randall, A & Case, CP, 2014, ‘Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions’. Experimental Neurology. MacVicar, T & Lane, JD, 2014, ‘Impaired OMA1 dependent OPA1 cleavage and reduced DRP1 fission activity combine to prevent mitophagy in OXPHOS dependent cells’. Journal of Cell Science., pp. 2313-2325 Petherick, KJ, Williams, AC, Lane, JD, Ordó?ez-Morán, P, Huelsken, J, Collard, TJ, Smartt, HJ, Batson, J, Malik, K, Paraskeva, C & Greenhough, A, 2013, ‘Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk’. The EMBO Journal, vol 32., pp. 1903 - 1916 Weir, HJM, Lane, JD & Balthasar, N, 2013, ‘SIRT3: A Central Regulator of Mitochondrial Adaptation in Health and Disease’. Genes & Cancer, vol 4., pp. 118-24 Betin, VMS, Singleton, BK, Parsons, SF, Anstee, DJ & Lane, JD, 2013, ‘Autophagy facilitates organelle clearance during differentiation of human erythroblasts: Evidence for a role for ATG4 paralogs during autophagosome maturation’. Autophagy, vol 9., pp. 881-893