Cullen, Pete - University of Bristol - School of Biochemistry

研究领域

Endosomal sorting and signaling

近期论文

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McGough, IJ, Steinberg, F, Jia, D, Barbuti, PA, McMillan, KJ, Heesom, KJ, Whone, AL, Caldwell, M, Billadeau, DD, Rosen, MK & Cullen, PJ, 2014, ‘Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.’. Current Biology, vol 24., pp. 1670-1676 Gallon, MJ, Clairfeuille, T, Steinberg, F, Mas, C, Ghai, R, Sessions, RB, Teasdale, RD, Collins, BM & Cullen, PJ, 2014, ‘A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.’. Proceedings of the National Academy of Sciences of the United States of America. Steinberg, F, Gallon, MJ, Winfield, MO, Thomas, EC, Bell, AJ, Heesom, KJ, Tavare, JM & Cullen, PJ, 2013, ‘A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.’. Nature Cell Biology, vol 15., pp. 461-471 van Weering, JRT, Sessions, RB, Traer, CJ, Kloer, DP, Bhatia, VK, Stamou, D, Carlsson, SR, Hurley, JH & Cullen, PJ, 2012, ‘Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules’. EMBO Journal, vol 31., pp. 4466-4480 Steinberg, F, Heesom, K, Bass, M & Cullen, P, 2012, ‘SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways’. The Journal of Cell Biology, vol 197., pp. 219 - 230 Harterink, M, Port, F, Lorenowicz, M, McGough, I, Silhankova, M, Betist, M, van Weering, J, van Heesbeen, R, Middlekoop, T, Basler, K, Cullen, P & Korswagen, H, 2011, ‘A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion’. Nature Cell Biology, vol 13 ., pp. 914 - 923 Wassmer, T, Attar, N, Harterink, M, van Weering, J, Traer, C, Oakley, J, Gould, B, Stephens, D, Verkade, P, Korswagen, H & Cullen, P, 2009, ‘The retomer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network’. Developmental Cell, vol 17 (1)., pp. 110 - 122 Traer, C, Rutherford, A, Palmer, K, Wassmer, T, Oakley, J, Attar, N, Carlton, J, Kremerskothen, J, Stephens, D & Cullen, P, 2007, ‘SNX4 co-ordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment’. Nature Cell Biology, vol 9 (12)., pp. 1370 - 1380 Carlton, J, Bunjy, M, Peter, B, Oorschot, V, Rutherford, A, Mellor, H, Klumperman, J, McMahon, H & Cullen, P, 2004, ‘Sorting Nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides’. Current Biology, vol 14 (20)., pp. 1791 - 1800 Venkateswarlu, K, Oatey, P, Tavaré, J & Cullen, P, 1998, ‘Insulin dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase’. Curr. Biol, vol 8., pp. 463 - 466