Adams, Jo - University of Bristol - School of Biochemistry

个人简介

1981. B.A. Cantab (Natural Sciences, Biological) 1985. M.A. Cantab. 1987. Ph.D. University of London. 1987-1990. Post-doctoral researcher, Imperial Cancer Research Fund, London. (Laboratory of Fiona Watt). 1990-1991. EMBO Long Term Fellow, Vascular Research Division, Brigham and Women's Hospital, Harvard University. (Laboratory of Jack Lawler). 1992-1994. HFSPO Long Term Fellow, Vascular Research Division, Brigham and Women's Hospital, Harvard University. (Laboratory of Jack Lawler). 1994-2004 (held until 2002). Wellcome Trust Senior Fellow in Basic Biomedical Research, MRC-LMCB, University College London. Affiliated with Dept. of Biochemistry and Molecular Biology, University College London. 2002-2009. Dept of Cell Biology, Lerner Research Institute, Cleveland Clinic. 2009- School of Biochemistry, University of Bristol.

研究领域

Role of Signaling to the Cytoskeleton by the Extracellular Matrix in Cell Motility Processes

近期论文

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Adams, J & Hellewell, AL, 2015, ‘Insider Trading: Extracellular Matrix Proteins and their Non-Canonical Intracellular Roles’. BioEssays, vol 38., pp. 77-88 Tu, H, Huhtala, P, Lee, H-M, Adams, J & Pihlajaniemi, T, 2015, ‘Membrane-associated collagens with interrupted triple-helices (MACITs): evolution from a bilaterian common ancestor and functional conservation in C. elegans’. BMC Evolutionary Biology, vol 15. Jayo, A, Parsons, M & Adams, JC, 2012, ‘A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability’. BMC Biology, vol 10., pp. 1-19 Kim, DJ, Christofidou, ED, Keene, DR, Milde, MH & Adams, JC, 2015, ‘Inter-Molecular Interactions Of Thrombospondins Drive Their Accumulation In Extracellular Matrix’. Molecular biology of the cell. Williams, F, Tew, HA, Paul, CE & Adams, JC, 2014, ‘The predicted secretomes of Monosiga brevicollis and Capsaspora owczarzaki, close unicellular relatives of metazoans, reveal new insights into the evolution of the metazoan extracellular matrix’. Matrix Biology. Tan, Y, Lewis, SJ, Adams, JC & Martin, RM, 2013, ‘Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis’. BMC Medicine, vol 11. Hellewell, AL, Gong, X, Sch?rich, K, Christofidou, E & Adams, J, 2015, ‘Modulation of the extracellular matrix patterning of thrombospondins by actin dynamics and thrombospondin oligomer state’. Bioscience Reports, vol 35. Adams, J & Brancaccio, A, 2015, ‘The evolution of the dystroglycan complex, a major mediator of muscle integrity’. Biology Open, vol 4., pp. 1163-1179 Adams, JC & Adams, J, 2014, ‘Fascin-1 as a biomarker and prospective therapeutic target in colorectal cancer’. Expert review of molecular diagnostics., pp. 1-8 Harrison, S, Lewis, SJ, Hall, AJ, Vuckovic, D, Girotto, G, Martin, RM & Adams, JC, 2015, ‘Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium’. BMC Medical Genomics, vol 8.