个人简介
Prof. Smart graduated in 1979 with a BSc (Hons) degree in Pharmacy, Brighton Polytechnic (now the University of Brighton), and completed his pharmacy preregistration training year with Cyanamid of Great Britain Ltd, Gosport and Portsmouth Area Hospitals.
He then studied for PhD degree at the Welsh School of Pharmacy, U.W.I.S.T. before managing his own community pharmacy business for four years. In 1988 he was appointed Lecturer in Pharmaceutics, the School of Pharmacy and Biomedical Science, Portsmouth Polytechnic (now the University of Portsmouth), then became a Reader in Pharmaceutical Sciences (1997) and then Head of the School from August 1997 to September 2002.
During this period the School flourished, scoring highly in the research assessment exercise and subject reviews. He also led the School into the pioneering ‘New Generation’ interprofessional education project in collaboration with the University of Southampton. In February 2004 he returned to the University of Brighton as Head of the School of Pharmacy and Biomolecular Sciences and Professor of Pharmaceutical Sciences.
研究领域
Prof. Smart’s research interests are in drug delivery using bioadhesive materials, specifically hydrophilic macromolecules and lectins; the multifunctional properties of these materials being of particular interest. Target sites investigated within the body include the eye, mouth, oesophagus, stomach and colon. He is also leading in the development of a UK-wide drug delivery network, as well as pursuing an interest in the quality and distribution of substandard medicines in developing countries
近期论文
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Smart, John, Dunkley, S., Tsibouklis, J. and Young, S. (2015) An evaluation of the adhesion of solid oral dosage form coatings to the oesophagus International Journal of Pharmaceutics, 496 (2). pp. 299-303. ISSN 0378-5173
Smart, John (2015) Principles of Bioadhesion In: Bianco-Peled, H. and Davidovich-Pinhas, M., eds. Bioadhesion and Biomimetics: From Nature to Applications. Pan Stanford Publishing, Singapore, pp. 3-21. ISBN 9789814463980
Smart, John (2014) Theories of mucoadhesion In: Khutoryanskiy, Vitaliy, ed. Mucoadhesive materials and drug delivery systems. John Wiley & Sons Ltd, Chichester, pp. 159-174. ISBN 9781119941439
Smart, John, Dunkley, S., Tsibouklis, J. and Young, S. (2013) An in vitro model for the evaluation of the adhesion of solid oral dosage forms to the oesophagus International Journal of Pharmaceutics, 447 (1-2). ISSN 0378-5173
Smart, John (2012) Conference report: Nasal and Buccal Drug Delivery: Management Forum Conference Therapeutic Delivery, 3 (7). ISSN 2041-5990
Keegan, G.M., Smart, John, Ingram, Matthew, Barnes, Lara-Marie, Burnett, G.R. and Rees, G.D. (2012) Chitosan microparticles for the controlled delivery of fluoride Journal of Dentistry, 40 (3). pp. 229-240. ISSN 0300-5712
Smart, John (2011) Drug delivery systems and their potential for use in battlefield situations In: Mikhalovsky, S. and Khajibaev, A., eds. Biodefence. NATO Science for Peace and Security Series A: Chemistry and Biology (3). Springer, pp. 117-124.
Smart, John and Keegan, Gemma (2010) Buccal drug delivery systems In: Wen, Hong and Park, Kinam, eds. Oral controlled release formulation design and drug delivery: theory to practice. John Wiley & Sons, New Jersey, pp. 169-184. ISBN 9780470253175
Gullick, D.R., Ingram, Matthew, Pugh, W.J., Cox, P.A., Gard, Paul and Smart, John (2009) Metabolism of captopril carboxyl ester derivatives for percutaneous absorption Journal of Pharmacy & Pharmacology, 61 (2). pp. 159-165. ISSN 0022-3573
Churchley, D., Rees, G.D., Smart, John and Tsibouklis, J. (2008) Fluoropolymers as low-surface-energy tooth coatings for oral care International Journal of Pharmaceutics, 352 (1-2). pp. 44-49. ISSN 0378-5173
Roldo, M., Barbu, E., Brown, J.F., Laight, D.W., Smart, John and Tsibouklis, J. (2007) Azo compounds in colon-specific drug delivery Expert Opinion on Drug Delivery, 4 (5). pp. 547-560. ISSN 1742-5247
Keegan, G., Smart, John, Ingram, Matthew, Barnes, Lara-Marie, Rees, G. and Burnett, G. (2007) An in vitro assesment of bioadhesive zinc/carbomer complexes for antimicrobial therapy within the oral cavity International Journal of Pharmaceutics, 340 (1-2). pp. 92-96. ISSN 0378-5173
Moss, G.P., Gullick, D.R., Cox, P.A., Alexander, C., Ingram, Matthew, Smart, John and Pugh, W.J. (2006) Design, synthesis and characterization of captopril prodrugs for enhanced percutaneous absorption Journal of Pharmacy and Pharmacology, 58 (2). pp. 167-177. ISSN 0022-3573
Smart, John (2005) The basics and underlying mechanisms of mucoadhesion Advanced Drug Delivery Reviews, 57 (11). pp. 1556-1568. ISSN 0169-409X
Kockisch, S., Rees, G.D., Tsibouklis, J. and Smart, John (2005) Mucoadhesive, triclosan-loaded polymer microspheres for application to the oral cavity: preparation and controlled release characteristics European Journal of Pharmaceutics and Biopharmaceutics, 59 (1). pp. 207-216.
Kockisch, S., Rees, G.D., Young, S.A., Tsibouklis, J. and Smart, John (2004) In situ evaluation of drug-loaded microspheres on a mucosal surface under dynamic test conditions International Journal of Pharmaceutics, 276 (1-2). pp. 51-58.
Smart, John (2004) Lectin-mediated drug delivery in the oral cavity Advanced Drug Delivery Reviews, 56 (4). pp. 481-489. ISSN 0169-409X
Smart, John (2004) Recent developments in the use of bioadhesive systems for delivery of drugs to the oral cavity Critical Reviews in Therapeutic Drug Carrier Systems, 21 (4). pp. 319-344. ISSN 0743-4863
Smart, John, Riley, R.G., Tsibouklis, J., Young, S.A., Hampson, F.C., Davis, J.A., Kelly, G., Dettmar, P.W. and Wilber, W.R. (2003) The retention of 14C-labelled poly(acrylic acids) on gastric and oesophageal mucosa: an in vitro study European Journal of Pharmaceutical Sciences, 20 (1). pp. 83-90. ISSN 0928-0987
Kockisch, S., Rees, G.D., Young, S.A., Tsibouklis, J. and Smart, John (2003) Polymeric microspheres for drug delivery to the oral cavity: An in vitro evaluation of mucoadhesive potential European Journal of Pharmaceutical Sciences, 92 (8). pp. 1614-1623.